Octyl p-methoxycinnamate loaded microemulsion based on Ocimum basilicum essential oil. Characterization and analytical studies for potential cosmetic applications

Volpe, Verónica; Nascimento, Danielle Silva Do; Insausti, Matías; Grünhut, Marcos

doi:10.1016/j.colsurfa.2018.02.070

Cited by 32 publications

(16 citation statements)

References 21 publications

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“…[1][2][3][4] Like liposomes, microemulsions have also hydrophobic and hydrophilic compartmentalized micro-domains, in which hydrophilic and lipophilic drug molecules could be encapsulated and stabilized. [5][6][7] In addition, microemulsions are the subject of many potential applications in detergents, 8 lubrication, 9 phytosanitary, 10 cosmetics, 11 formulation of paints, 12 and advanced petrol extraction. 13 This growing interest in microemulsions also results from a better understanding of their physicochemical properties.…”

Section: Introductionmentioning

confidence: 99%

Effect of hydrophobically modified PEO polymers (PEO-dodecyl) on oil/water microemulsion properties: in vitro and in silico investigations

et al. 2021

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Section: Introductionmentioning

confidence: 99%

Effect of hydrophobically modified PEO polymers (PEO-dodecyl) on oil/water microemulsion properties: in vitro and in silico investigations

et al. 2021

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“…Moreover, it is not toxic, non-sensitizing and non-irritating, thus it can be considered an excellent candidate. Some authors reported also the use of non-ionic surfactants such as Surfynol (2,4,7,9-Tetramethyl-5-decyne-4,7-diol ethoxylate), decaethylene glycol mono-dodecyl ether and polyoxyethylene castor oil derivatives [71][72][73]. In addition to the aforementioned non-ionic surfactants, an interesting alternative is represented by the tri-block polymeric surfactants.…”

Section: Surfactantmentioning

confidence: 99%

“…However, ethanol, penetrating the surfactant film at the interface, leads to a decrease of the bending moduli of this film, favouring the formation of water-dilutable MEs. Volpe et al reported the encapsulation of octyl p-methoxycinnamate into a MEs stabilized by glycol mono-dodecyl ether (surfactant) and ethanol (co-surfactant) [72]. Through pseudo-ternary phase diagrams they investigated the optimal surfactant/co-surfactant ratios.…”

Section: Co-surfactantmentioning

confidence: 99%

An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and Stability

et al. 2020

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The interest around essential oils is constantly increasing thanks to their biological properties exploitable in several fields, from pharmaceuticals to food and agriculture. However, their widespread use and marketing are still restricted due to their poor physico-chemical properties; i.e., high volatility, thermal decomposition, low water solubility, and stability issues. At the moment, the most suitable approach to overcome such limitations is based on the development of proper formulation strategies. One of the approaches suggested to achieve this goal is the so-called encapsulation process through the preparation of aqueous nano-dispersions. Among them, micro- and nanoemulsions are the most studied thanks to the ease of formulation, handling and to their manufacturing costs. In this direction, this review intends to offer an overview of the formulation, preparation and stability parameters of micro- and nanoemulsions. Specifically, recent literature has been examined in order to define the most common practices adopted (materials and fabrication methods), highlighting their suitability and effectiveness. Finally, relevant points related to formulations, such as optimization, characterization, stability and safety, not deeply studied or clarified yet, were discussed.

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“…The perennial herb Ocimum basilicum (family Lamiaceae), commonly known as basil, is valued worldwide for its culinary uses, but its applications go well beyond that. Basil and its essential oil are often used in traditional medicine (Irondi et al 2016;Ezeani et al 2017;Bae et al 2020), cosmetics (Vivas Castaño et al 2016;Volpe et al 2018;Yeşil et al 2020), and pharmacology (Sestili et al 2018;Zhan et al 2020). Among the pharmacologically interesting compounds found in basil are linalool (Medeiros Venancio et al 2016), rosmarinic (Kwon et al 2019), oleanolic (OA; Qamar et al 2020) and ursolic acid (UA; Arshad Qamar et al 2010;Kümmritz et al 2014).…”

Section: Introductionmentioning

confidence: 99%

Establishment and triterpenoid production of Ocimum basilicum cambial meristematic cells

Mehring

Haffelder

Chodorski

et al. 2020

Plant Cell Tiss Organ Cult

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The application of plant suspension culture to produce valuable compounds, such as the triterpenoids oleanolic acid and ursolic acid, is a well-established alternative to the cultivation of whole plants. Cambial meristematic cells (CMCs) are a growing field of research, often showing superior cultivation properties compared to their dedifferentiated cell (DDC) counterparts. In this work, the first-time establishment of O. basilicum CMCs is demonstrated. DDCs and CMCs were cultivated in shake flasks and wave-mixed disposable bioreactors (wDBRs) and evaluated regarding triterpenoid productivity and biomass accumulation. CMCs showed characteristic small vacuoles and were found to be significantly smaller than DDCs. Productivities of oleanolic and ursolic acid of CMCs were determined at 3.02 ± 0.76 mg/(l*d) and 4.79 ± 0.48 mg/(l*d) after 19 days wDBR cultivation, respectively. These values were consistently higher than any productivities determined for DDCs over the observed cultivation period of 37 days. Elicitation with methyl jasmonate of DDCs and CMCs in shake flasks resulted in increased product contents up to 48 h after elicitor addition, with the highest increase found in CMCs at 232.30 ± 19.33% (oleanolic acid) and 192.44 ± 18.23% (ursolic acid) after 48 h.

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Octyl p-methoxycinnamate loaded microemulsion based on Ocimum basilicum essential oil. Characterization and analytical studies for potential cosmetic applications

Cited by 32 publications

References 21 publications

Effect of hydrophobically modified PEO polymers (PEO-dodecyl) on oil/water microemulsion properties: in vitro and in silico investigations

Effect of hydrophobically modified PEO polymers (PEO-dodecyl) on oil/water microemulsion properties: in vitro and in silico investigations

An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and Stability

Establishment and triterpenoid production of Ocimum basilicum cambial meristematic cells

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