OCT in Toxic and Nutritional Optic Neuropathies

Grzybowski, Andrzej; Obuchowska, Iwona; Arndt, Carl

doi:10.1007/978-3-030-26269-3_18

Cited by 2 publications

(2 citation statements)

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“…The use of optic nerve head OCT for diagnosis and monitoring nutritional optic neuropathies is still debated, but it may be helpful in detecting the thinning of RNFL before fundus changes appear. Thinning of RNFL begins in papillomacular bundle and then involves all the quadrants [41,42] (Figure 2). Imaging studies include MRI of the optic nerves, chiasm, and optic tract, which is usually performed to exclude a compressive or demyelinating lesion [43] (Table 2).…”

Section: Diagnosismentioning

confidence: 99%

Nutritional Optic Neuropathies: State of the Art and Emerging Evidences

et al. 2020

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Nutritional optic neuropathy is a cause of bilateral, symmetrical, and progressive visual impairment with loss of central visual acuity and contrast sensitivity, dyschromatopsia, and a central or centrocecal scotoma. The clinical features are not pathognomonic, since hereditary and toxic forms share similar signs and symptoms. It is becoming increasingly common due to the widespread of bariatric surgery and strict vegetarian or vegan diets, so even the scientific interest has recently increased. In particular, recent studies have focused on possible pathogenetic mechanisms, and on novel diagnostic and therapeutic strategies in order to prevent the onset, make a prompt diagnosis and an accurate nutritional supplementation, and to avoid irreversible optic nerve atrophy. Nowadays, there is clear evidence of the role of cobalamin, folic acid, thiamine, and copper, whereas further studies are needed to define the role of niacin, riboflavin, and pyridoxine. This review aims to summarize the etiology, diagnosis, and treatment of nutritional optic neuropathy, and it is addressed not only to ophthalmologists, but to all physicians who could come in contact with a patient with a possible nutritional optic neuropathy, being a fundamental multidisciplinary approach.

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Section: Diagnosismentioning

confidence: 99%

Nutritional Optic Neuropathies: State of the Art and Emerging Evidences

et al. 2020

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“…Several modalities have been used for the diagnosis and follow-up of the patients. OCT is used to detect the thickening of the RNFL in the acute phase and thinning and atrophy in the late stage [ 93 ]. Fluorescein angiography can also evaluate retinal vascularity in toxic neuropathies but is not always accessible because of various side effects of dye-like anaphylaxis, nausea, and renal impairment.…”

Section: Papilledemamentioning

confidence: 99%

The Role of Optical Coherence Tomography Angiography in Optic Nerve Head Edema: A Narrative Review

Karrabi

Hooshmandi

Amirabadi

et al. 2022

Journal of Ophthalmology

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Optic nerve head (ONH) edema is a clinical manifestation of many ocular and systemic disorders. Ocular and central nervous system imaging has been used to differentiate the underlying cause of ONH edema and monitor the disease course. ONH vessel abnormalities are among the earliest signs of impaired axonal transportation. Optical coherence tomography angiography (OCTA) is a noninvasive method for imaging ONH and peripapillary vessels and has been used extensively for studying vascular changes in ONH disorders, including ONH edema. In this narrative review, we describe OCTA findings of the most common causes of ONH edema and its differential diagnoses including ONH drusen.

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OCT in Toxic and Nutritional Optic Neuropathies

Cited by 2 publications

References 56 publications

Nutritional Optic Neuropathies: State of the Art and Emerging Evidences

Nutritional Optic Neuropathies: State of the Art and Emerging Evidences

The Role of Optical Coherence Tomography Angiography in Optic Nerve Head Edema: A Narrative Review

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