OCT and OCTA evaluation of vascular and morphological structures in the retina in recovered pediatric patients with COVID-19

Demir, Semra Tiryaki; Dalgıç, Nazan; Yeşiltaş, Sümeyra Keleş; Ozyurek, Emine Betul Akbas; Karapapak, Murat; Uzun, Saniye Uke; Güven, Dilek

doi:10.1016/j.pdpdt.2022.103157

Cited by 5 publications

(1 citation statement)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recent studies have shown conflicting findings regarding retinal alterations in patients after SARS‐CoV‐2 infection. Compared with the RNFL and GCIPL of healthy controls, thicker RNFL and GCIPL were observed in patients after COVID‐19 infection 9,10 . Akpolat et al reported the thickening of pRNFL and thinning of GCIPL in pediatric patients recovering from COVID‐19 11 .…”

Section: Discussionmentioning

confidence: 99%

Assessment of alterations in the retina and vitreous in pre‐ and post‐COVID‐19 patients using swept‐source optical coherence tomography and angiography: A comparative study

Gao,

Zhang,

Mou

et al. 2023

Journal of Medical Virology

View full text Add to dashboard Cite

Ocular manifestations have been well recognized in coronavirus disease 2019 (COVID‐19) outbreak. Several studies have detected ocular manifestations in patients after COVID‐19. However, little is known about the retinal and vitreal alterations in patients before and after COVID‐19 infection. This study aimed to investigate the retinal and vitreal alterations in patients before and after contracting COVID‐19 infection using swept‐source optical coherence tomography (SS‐OCT) and angiography (SS‐OCTA). A total of 38 participants (76 eyes) were enrolled and followed‐up 1 month after COVID‐19 infection. Then, 26 patients (52 eyes) were evaluated 3 months after COVID‐19 infection. Compared with the pre‐COVID‐19 status, patients with 1‐ and 3‐month post‐COVID‐19 statuses had significant thinning of ganglion cell and inner plexiform layer, thickening of inner nuclear layer, a decrease in the vessel density (VD) of superficial vascular complex, and an increase in the VD of deep vascular complex. Meanwhile, alteration in parameters of foveal avascular zone (all p < 0.05) and hyper‐reflective dots in the vitreous of 27 patients (54 eyes) (71.1% vs. pre‐COVID‐19, 34.2%, p = 0.006) were observed. These findings suggest significantly retinal and vitreal alterations occurred in patients after COVID‐19 infection, possibly due to direct or indirect virus‐induced injuries. Further longitudinal studies are required to investigate the long‐term effects of COVID‐19 infection on the human eyes.

show abstract

Section: Discussionmentioning

confidence: 99%