Occurrennce and impact of community‐acquired and nosocomial rotavirus infections — a hospital‐based study over 10 y

Berner, Reinhard; Schumacher, R. F.; Hameister, S; Förster, Johannes

doi:10.1111/j.1651-2227.1999.tb14326.x

Cited by 70 publications

(45 citation statements)

References 17 publications

(20 reference statements)

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“…Moreover, the virus is very difficult to eradicate and remains viable on dry surfaces for 1 -10 days and on human hands for at least 4 hours [7] [8]. These characteristics can explain why RV is a cause of nosocomial infections [9].…”

Section: Introductionmentioning

confidence: 99%

Burden of rotavirus infections in Liguria, northern Italy: hospitalisations and potential savings by vaccination

Panatto

Amicizia

Giacchino

et al. 2011

Eur J Clin Microbiol Infect Dis

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Purpose We evaluated the rates of gastroenteritis admissions to the emergency department and of rotavirusrelated hospitalisations in children ≤5 years in 2006 at an Italian paediatric hospital; we calculated the number of rotavirus cases avoidable through the universal vaccination of children.Methods Epidemiological data were extracted from the Data Elaboration Centre. To calculate the hospitalisation rate due to rotavirus, the virus was sought in the faeces of children hospitalised for acute gastroenteritis by means of rapid immunochromatographic assay.Results Emergency department admissions due to gastroenteritis numbered 2396 (11.58% of total admissions).Of these, 276 children (11.52%) were examined and then sent home; 1286 (53.67%) were kept in short observation and 776 (32.38%) were hospitalised. In 27.83% of hospitalised cases, the rotavirus test proved positive. The RV hospitalization rate was 55 per 10000 children ≤5 years in Genoa in 2006. In 85.6% of hospitalised patients with community-acquired rotavirus infection, the disease was severe. ConclusionsThe number of avoidable cases confirmed that the vaccination of children ≤1 year of age could reduce the burden of rotavirus infection, especially with regard to hospitalisation (45 per 10000 children ≤5 years) and admissions to short observation (85 per 10000), generating benefits for Italian healthcare system.

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Section: Introductionmentioning

confidence: 99%

Burden of rotavirus infections in Liguria, northern Italy: hospitalisations and potential savings by vaccination

Panatto

Amicizia

Giacchino

et al. 2011

Eur J Clin Microbiol Infect Dis

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“…Data about RV morbidity in Europe are available mainly for southern [2,9,26], northern [16,31], and western parts [1,3,6,11,28]. Only a few studies were performed in eastern Europe [22].…”

Section: Introductionmentioning

confidence: 99%

A 4-year study on clinical characteristics of children hospitalized with rotavirus gastroenteritis

et al. 2009

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Rotavirus (RV) is a frequent cause of severe gastroenteritis (GE) in children. With the licensure of new RV vaccines, data on the burden of disease are important regarding immunization strategies. We reviewed the medical records of children hospitalized with RV infection in our institution between July 2002 and March 2006. Relevant data were extracted in a standardized fashion from records of hospitalized children with a positive RV antigen test in a stool sample. Severity of disease was graded by the 20-point Vesikari score. Population data were obtained from the Federal Office of Statistics. Six hundred eighty-six RVGE were identified and records of 608 hospitalizations (in 607 children) were available. In 539 (89%) cases, RVGE was the primary reason for hospitalization and 69 (11%) were nosocomial infections; yearly peaks occurred between February and May. Cumulative incidence of RVGE was 26.7/1,000 children <3 years of age. Median age of 539 children (55.6% male) with primary RVGE was 1.4 years and median stay in the hospital for both community acquired and nosocomial RVGE was 4 days (interquartile range 3-5). Thirtypercent and 94% of RV hospitalizations were in children <1 and <3 years of age, respectively. Mean Vesikari score was 15 (range 6-20; 96% >11). Intravenous fluids were administered in 378 (70%) patients, 130 (24%) patients were rehydrated via nasogastral tube, and 31 (5.7%) received rehydration by mouth. RVGE causes a substantial burden in children with an estimated risk for hospitalization due to RVGE of one in 37 children <3 years of age.

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“…Asymptomatic rotavirus gastroenteritis is frequently seen in children younger than six months of age, especially in newborns [14,15]. The median age of our patients was eight months.…”

Section: Discussionmentioning

confidence: 99%

The effects of nosocomial rotavirus gastroenteritis on the length of hospital stay and cost

Gündeşli̇oğlu

Tekin

Çevik

et al. 2016

J Infect Dev Ctries

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Introduction: In this study, the goal was to evaluate the impact of nosocomial rotavirus gastroenteritis in pediatric patients by determining the incidence of nosocomial rotavirus gastroenteritis, the resulting duration of hospital stay, and direct cost. To our knowledge, this is the first study in Turkey that evaluates the impact of pediatric nosocomial rotavirus gastroenteritis on duration of hospital stay and calculates the direct cost. Methodology: Forty-nine patients who were diagnosed with nosocomial rotavirus gastroenteritis and hospitalized were included in the study. Nosocomial infection rates, organ systems affected by the nosocomial infections, and patients who had nosocomial rotavirus gastroenteritis were identified. A direct cost analysis of patients who were diagnosed with nosocomial rotavirus gastroenteritis was performed using copies of the invoices for the hospital bills. Results: During the study period, there were 49 cases of nosocomial rotavirus gastroenteritis. The length of hospitalization was extended, on average, by more than 6.3 days in cases of nosocomial rotavirus gastroenteritis. The cost of hospitalization for patients with nosocomial rotavirus gastroenteritis was on average 1,554 ± 2,067 US dollars, compared to a cost of only 244 ± 103 US dollars for patients who did not have nosocomial rotavirus gastroenteritis. This difference in cost was statistically significant (p < 0.05). Conclusions: Nosocomial rotavirus gastroenteritis is important because it significantly prolongs hospital stay and increases the social and economic burden of the hospitalization. Nosocomial rotavirus gastroenteritis can be reduced with prevention measures such as handwashing, isolation, and cohorting.

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Occurrennce and impact of community‐acquired and nosocomial rotavirus infections — a hospital‐based study over 10 y

Cited by 70 publications

References 17 publications

Burden of rotavirus infections in Liguria, northern Italy: hospitalisations and potential savings by vaccination

Burden of rotavirus infections in Liguria, northern Italy: hospitalisations and potential savings by vaccination

A 4-year study on clinical characteristics of children hospitalized with rotavirus gastroenteritis

The effects of nosocomial rotavirus gastroenteritis on the length of hospital stay and cost

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