Occurrence, spatial-temporal distribution and ecological risks of pharmaceuticals and personal care products response to water diversion across the rivers in Nanjing, China

Yang, Huifen; Lu, Guanghua; Yan, Zhenhua; Liu, Jianchao; Dong, Huike; Jiang, Runren; Zhou, Ranran; Zhang, Peng; Sun, Yu; Nkoom, Matthew

doi:10.1016/j.envpol.2019.113132

Cited by 44 publications

(23 citation statements)

References 61 publications

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“…One millilitre of the supernatant from each set of sample was withdrawn, then filtered with 0.45 µm glass fibre filters. In addition, the concentrations of the SMX and EHMC were detected using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS) in accordance with our previous work [33]. These analyses had detection limits of 0.2 and 0.3 ng L −1 for SMX and EHMC, respectively.…”

Section: Slurry Incubation Experiments For the Removal Of Smx And Ehmcsupporting

confidence: 76%

Effects of Sulfamethoxazole and 2-Ethylhexyl-4-Methoxycinnamate on the Dissimilatory Nitrate Reduction Processes and N2O Release in Sediments in the Yarlung Zangbo River

Xue

2020

IJERPH

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The nitrogen pollution of rivers as a global environmental problem has received great attentions in recent years. The occurrence of emerging pollutants in high-altitude rivers will inevitably affect the dissimilatory nitrate reduction processes. In this study, sediment slurry experiments combined with 15N tracer techniques were conducted to investigate the influence of pharmaceutical and personal care products (alone and in combination) on denitrification and the anaerobic ammonium oxidation (anammox) process and the resulting N2O release in the sediments of the Yarlung Zangbo River. The results showed that the denitrification rates were inhibited by sulfamethoxazole (SMX) treatments (1–100 μg L−1) and the anammox rates decreased as the SMX concentrations increased, which may be due to the inhibitory effect of this antibiotic on nitrate reducing microbes. 2-Ethylhexyl-4-methoxycinnamate (EHMC) impacted nitrogen transformation mainly though the inhibition of the anammox processes. SMX and EHMC showed a superposition effect on the denitrification processes. The expression levels of the denitrifying functional genes nirS and nosZ were decreased and N2O release was stimulated due to the presence of SMX and/or EHMC in the sediments. To the best of our knowledge, this study is the first to report the effects of EHMC and its mixtures on the dissimilatory nitrate reduction processes and N2O releases in river sediments. Our results indicated that the widespread occurrence of emerging pollutants in high-altitude rivers may disturb the nitrogen transformation processes and increase the pressure of global warming.

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Section: Slurry Incubation Experiments For the Removal Of Smx And Ehmcsupporting

confidence: 76%

Effects of Sulfamethoxazole and 2-Ethylhexyl-4-Methoxycinnamate on the Dissimilatory Nitrate Reduction Processes and N2O Release in Sediments in the Yarlung Zangbo River

Xue

2020

IJERPH

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“…Furthermore, sunscreens that are adsorbed onto the surface of nanoplastic particles are difficult to degrade by current wastewater treatment and enter the aquatic environment. , Currently, there are many reports on the occurrence and toxicity of sunscreens, including the most common component butyl methoxydibenzoylmethane (BMDBM) in the formulation of sunscreens . Sunscreens are widely detected in surface water, suspended particulate matter, sediment, and various organisms in urban rivers, and BMDBM is one of the main detected substances. , The maximum concentrations of BMDBM were 116 ng/L in the Yangtze River, China; 721 ng/L in the surface water of Hong Kong, China; and 70 ng/L in the Arctic Ocean. , In a laboratory exposure study, BMDBM was found to be bioconcentrated in crucian carp (Carassius auratus) and induced toxic responses of the nervous system and antioxidant defense system . At present, co-exposure to micro- and nanoplastics and other pollutants such as heavy metals, polycyclic aromatic hydrocarbons, herbicides, or pharmaceuticals has caused a widespread concern. − However, the combined effects of nanoplastics and sunscreens are rarely reported.…”

Section: Introductionmentioning

confidence: 99%

Effects of Nanoplastics and Butyl Methoxydibenzoylmethane on Early Zebrafish Embryos Identified by Single-Cell RNA Sequencing

Liu

Wang

Ling

et al. 2021

Environ. Sci. Technol.

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Nanoplastics with small particle sizes and high surface area/volume ratios easily absorb environmental pollutants and affect their bioavailability. In this study, polystyrene nanoplastic beads (PS-NPBs) with a particle size of 100 nm and butyl methoxydibenzoylmethane (BMDBM) sunscreen in personal-care products were chosen as target pollutants to study their developmental toxicity and interactive effects on zebrafish embryos. The exposure period was set from 2 to 12 h postfertilization (hpf). BMDBM and PS-NPBs significantly upregulated genes related to antioxidant enzymes and downregulated the gene expression of aromatase and DNA methyltransferases, but the influenced genes were not exactly the same. The combined exposure reduced the adverse effects on the expression of all genes. With the help of the single-cell RNA sequencing technology, neural mid cells were identified as the target cells of both pollutants, and brain development, head development, and the notch signaling pathway were the functions they commonly altered. The key genes and functions that are specifically affected by BMDBM and/or PS-NPBs were identified. BMDBM mainly affects the differentiation and fate of neurons in the central nervous system through the regulation of her5, her6, her11, lfng, pax2a, and fgfr4. The PS-NPBs regulate the expression of olig2, foxg1a, fzd8b, six3a, rx1, lhx2b, nkx2.1a, and sfrp5 to alter nervous system development, retinal development, and stem cell differentiation. The phenotypic responses of zebrafish larvae at 120 hpf were tested, and significant inhibition of locomotor activity was found, indicating that early effects on the central nervous system would have a sustained impact on the behavior of zebrafish.

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“…Natural processes mainly include climate change [2], rock mineral oxidation [2,3], soil weathering and erosion [2], seawater intrusion [4], and others. Anthropogenic activities are primarily comprised of domestic and municipal wastewater [4], industrial and agricultural effluents [4,5], water diversion projects [6], and others. Therefore, regular monitoring campaigns and evaluations of water quality are helpful in preventing water pollution and applying remedial measures [7,8].…”

Section: Introductionmentioning

confidence: 99%

“…Gao et al [35] applied the normal cloud-fuzzy variable set evaluation model to assess water quality in the lower reaches of the river in 2016. Yang et al [6] investigated the impacts of water diversion projects on the spatiotemporal distribution of pharmaceutical and personal care products (PPCPs) in the lower reaches of the river. On the temporal scale, the previous studies were constrained by short-term observation results, with only 1-2 years of measurement [34][35][36].…”

Section: Introductionmentioning

confidence: 99%

Spatiotemporal Analysis of Water Quality Using Multivariate Statistical Techniques and the Water Quality Identification Index for the Qinhuai River Basin, East China

Wang

Yang

et al. 2020

Water

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Monitoring water quality is indispensable for the identification of threats to water environment and later management of water resources. Accurate monitoring and assessment of water quality have been long-term challenges. In this study, multivariate statistical techniques (MST) and water quality identification index (WQII) were applied to analyze spatiotemporal variation in water quality and determine the major pollution sources in the Qinhuai River, East China. A rotated principal component analysis (PCA) identified three potential pollution sources during the wet season (mixed pollution, physicochemical, and nonpoint sources of nutrients) and the dry season (nutrient, primary environmental, and organic sources) and they explained 81.14% of the total variances in the wet season and 78.42% of total variances in the dry season. The result of redundancy analysis (RDA) showed that population density, urbanization, and wastewater discharge are the main sources of organic pollution, while agricultural fertilizer consumption and industrial wastewater discharge are the main sources of nutrients such as nitrogen and phosphorus. The water quality of the Qinhuai River basin was determined to be mainly Class III (slightly polluted) and Class IV (moderately polluted) based on WQII. Temporally, the change trend of WQII showed that water quality gradually deteriorated between 1990 and 2005, improved between 2006 and 2010, and then deteriorated again. Spatially, the WQII distribution map showed that areas with more developed urbanization were relatively more polluted. Our results show that MST and WQII are useful tools to help the public and decision makers to evaluate the water quality of aquatic environment.

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Occurrence, spatial-temporal distribution and ecological risks of pharmaceuticals and personal care products response to water diversion across the rivers in Nanjing, China

Cited by 44 publications

References 61 publications

Effects of Sulfamethoxazole and 2-Ethylhexyl-4-Methoxycinnamate on the Dissimilatory Nitrate Reduction Processes and N2O Release in Sediments in the Yarlung Zangbo River

Effects of Sulfamethoxazole and 2-Ethylhexyl-4-Methoxycinnamate on the Dissimilatory Nitrate Reduction Processes and N2O Release in Sediments in the Yarlung Zangbo River

Effects of Nanoplastics and Butyl Methoxydibenzoylmethane on Early Zebrafish Embryos Identified by Single-Cell RNA Sequencing

Spatiotemporal Analysis of Water Quality Using Multivariate Statistical Techniques and the Water Quality Identification Index for the Qinhuai River Basin, East China

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