Occurrence of microcystins in water, bloom, sediment and fish from a public water supply

Gürbüz, Fatma; Uzunmehmetoğlu, Oğuz Y.; Diler, Öznur; Metcalf, James S.; Codd, Geoffrey A.

doi:10.1016/j.scitotenv.2016.04.027

Cited by 61 publications

(36 citation statements)

References 65 publications

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“…Echinenone and myxoxanthophyll 2 are the most important pigments for detecting cyanobacteria in freshwater, because they occur in all the cultured cyanobacteria and are universally detected in many other species of cyanobacteria (Goodwin 1980, Rowan 1989, Roy et al 2011). However, the coccoid/ pico-sized cyanobacteria (e.g.…”

Section: Pigments For Chemotaxonomic Analysismentioning

confidence: 99%

“…Although fish accumulate microcystin mainly in the liver, they also accumulate it in muscle tissue and viscera, which is a risk to humans who eat the fish (Magalhães et al 2001, Soares et al 2004. In some cases, the dietary intake values of microcystins in fish have been found to be above the limits determined by international legislations (Hauser-Davis et al 2015, Gurbuz et al 2016. In humans, microcystin may also promote cancer due to chronic exposure to low microcystin concentrations in drinking water and probably also from eating fish (Ueno et al 1996, Zhou et al 2002.…”

Section: Introductionmentioning

confidence: 99%

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Characterization of phytoplankton by pigment analysis and the detection of toxic cyanobacteria in reservoirs with aquaculture production

Schlüter¹,

David²,

Jørgensen³

et al. 2018

Aquacult. Environ. Interact.

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Section: Pigments For Chemotaxonomic Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Characterization of phytoplankton by pigment analysis and the detection of toxic cyanobacteria in reservoirs with aquaculture production

Schlüter¹,

David²,

Jørgensen³

et al. 2018

Aquacult. Environ. Interact.

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“…The factors that influence cyanotoxin concentrations in fish likely include the concentration of the specific toxin(s) in the environment in combination with the period of exposure and fish metabolic processes (Jia et al, 2014;Gurbuz et al, 2016). Further, different cyanotoxin quantification methods could also introduce variability that may artificially enhance or inhibit detection of patterns in nature if toxin concentrations are over-or underestimated.…”

Section: Introductionmentioning

confidence: 99%

A Global Analysis of the Relationship between Concentrations of Microcystins in Water and Fish

2018

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Cyanobacteria, the primary bloom-forming organisms in fresh water, elicit a spectrum of problems in lentic systems. The most immediate concern for people and animals are cyanobacterial toxins, which have been detected at variable concentrations in water and fish around the world. Cyanotoxins can transfer through food webs, potentially increasing the risk of exposure to people who eat fish from affected waters, yet little is known about how cyanotoxins fluctuate in wild fish tissues. We collated existing studies on cyanotoxins in fish and fresh water from lakes around the world into a global dataset to test the hypothesis that cyanotoxin concentrations in fish increase with water toxin concentrations. We limited our quantitative analysis to microcystins because data on other cyanotoxins in fish were sparse, but we provided a qualitative summary of other cyanotoxins reported in wild, freshwater fish tissues. We found a positive relationship between intracellular microcystin in water samples and microcystin in fish tissues that had been analyzed by assay methods (enzyme-linked immunosorbent assay and protein phosphatase inhibition assay). We expected microcystin to be found in increasingly higher concentrations from carnivorous to omnivorous to planktivorous fishes. We found, however, that omnivores generally had the highest tissue microcystin concentrations. Additionally, we found contrasting results for the level of microcystin in different tissue types depending on the toxin analysis method. Because microcystin and other cyanotoxins have the potential to impact public health, our results underline the current need for comprehensive and uniform detection methods for the analysis of cyanotoxins in complex matrices.

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“…To reduce the risks posed by MCs, the World Health Organization (WHO) has established a provisional guideline of 1 μg L −1 MCs in water destined for use as human drinking water, and 20 μg L −1 for recreational waters . MCs, comprised of a family of potent hepatotoxins, are the cyanotoxins with the most frequent occurrence and they show the greatest resistance to degradation because of their stable cyclic peptide structure.…”

Section: Introductionmentioning

confidence: 99%

Direct Electrochemical Nano‐immunosensor for Microcystin‐LR in Seawater

et al. 2018

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Microcystins are potent hepatotoxins produced by cyanobacteria, which proliferate in wastewaters with high nutrient content. Due to their high toxicity and potential risk to human health, even at low concentrations, the development of a sensitive and rapid method for the monitoring of microcystin‐LR (MC‐LR) in water samples is of great importance. In this context, a new direct electrochemical nano‐immunosensor for MC‐LR detection using the liquid crystal (E)‐1‐decyl‐4‐[(4‐decyloxyphenyl)diazenyl]pyridinium bromide (Br‐Py) as a redox probe and gold nanoparticles stabilized in bovine serum albumin (AuNP‐BSA) is described herein. The microcystin‐LR antibody (anti‐MC‐LR) was covalently immobilized using N‐(3‐dimethylaminopropyl)‐N‐ethylcarbodiimide hydrochloride (EDC) and N‐hydroxysuccinimide (NHS) on an AuNP‐BSA/BrPy film. The proposed sensor response is based on the inhibition of the Br‐Py electrochemical signal after the specific interaction of MC‐LR with immobilized anti‐MC‐LR on the electrode surface. The electrochemical behavior of the immunosensor was studied by square‐wave voltammetry (SWV) and electrochemical impedance spectroscopy (EIS). Under optimized conditions, using SWV and an incubation time of 15 min, the immunosensor exhibits a linear response to MC‐LR concentrations of 0.05 to 500.0 ng mL−1 with a detection limit of 0.05 ng mL−1. The anti‐MC‐LR/AuNP‐BSA/Br‐Py/GCE was successfully applied in the determination of MC‐LR in spiked seawater samples.

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Occurrence of microcystins in water, bloom, sediment and fish from a public water supply

Cited by 61 publications

References 65 publications

Characterization of phytoplankton by pigment analysis and the detection of toxic cyanobacteria in reservoirs with aquaculture production

Characterization of phytoplankton by pigment analysis and the detection of toxic cyanobacteria in reservoirs with aquaculture production

A Global Analysis of the Relationship between Concentrations of Microcystins in Water and Fish

Direct Electrochemical Nano‐immunosensor for Microcystin‐LR in Seawater

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