Occurrence, Antibiotic Resistance and Pathogenicity of Non-O1 Vibrio cholerae in Moroccan Aquatic Ecosystems: A Review

Oufdou, Khalid; Mezrioui, Nour-Eddine

doi:10.5772/29377

Cited by 1 publication

(1 citation statement)

References 41 publications

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“…These serogroups may cause diarrheal diseases less severe than cholera and do not present epidemic potential (Wong et al, 2012). Although they normally do not produce a cholera toxin, they carry other virulent factors involved in the pathogenicity, including the production of hemolysins, proteases, hemagglutinins, and may have multiple drug resistance (Oufdou and Mezrioui, 2012). It is reported that in aquatic environment, one serogroup can be converted to another by homologous recombinations, or by mutation and/or rearrangement, as noticed in O139 lineage (Blokesch and Schoolnik, 2007).…”

Section: Introductionmentioning

confidence: 99%

Vibrio cholerae non-O1 in bivalve mollusks harvesting area in Bahia, Brazil

Silva¹,

Sousa²,

Saraiva³

et al. 2016

Afr. J. Microbiol. Res.

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The aim of this study was to characterize the antimicrobial resistance and pathogenicity potential of Vibrio cholerae isolates originated from water samples and bivalve mollusks. The strains were subjected to phenotypic identification and molecular confirmation using the species-specific initiator (OmpW); minimum inhibitory concentration (MIC) was determined; and the production of metallo-β-lactamases (MβLs) and virulence potential of the strains by using the initiator ctxAB (cholera toxin), tcp (toxin co-regulator pilus), rfbO1 (serogroup O1) and zot (zonula occludens toxin) were investigated. Six isolates of the bacterium (three from water and three from bivalve mollusks) were confirmed through the biochemical and specific gene detection tests. The isolates presented a high susceptibility toward the tested antimicrobials (91%) (10/11). One of the strains from water showing resistance to imipenem (MIC 20 µg), and producing MβLs did not show any involvement of plasmids. The genes related to the virulence were not detected; and all of the V. cholerae isolates belonged to the non-O1 serotype. However, the presence of an imipenem-resistant and MβLs-producing V. cholerae in a river mouth aquatic environment, which is a natural aviary of bivalve mollusks, represents a risk to the health of the population and alarms the public health agencies.

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Section: Introductionmentioning

confidence: 99%