Occurrence and Timing of Subsequent SARS-CoV-2 RT-PCR Positivity Among Initially Negative Patients

Long, David P.; Gombar, Saurabh; Hogan, Catherine A.; Greninger, Alexander L.; Shah, Vikas; Bryson-Cahn, Chloe; Stevens, Bryan; Jerome, Keith R.; Kong, Christina S.; Zehnder, James L.; Shah, Nigam H.; Weiss, Noel S.; Pinsky, Benjamin A.; Sunshine, Jacob

doi:10.1101/2020.05.03.20089151

Cited by 48 publications

(67 citation statements)

References 6 publications

(8 reference statements)

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“…Other researchers have also documented that repeat RT-PCR testing can yield positive results for patients with initial negative results, albeit at relatively low rates. 18 On the basis of our early experience, we instituted a protocol requiring at least 2 negative RT-PCR test results for symptomatic patients before discontinuing isolation.…”

Section: Discussionmentioning

confidence: 99%

Incidence of Nosocomial COVID-19 in Patients Hospitalized at a Large US Academic Medical Center

et al. 2020

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Section: Discussionmentioning

confidence: 99%

Incidence of Nosocomial COVID-19 in Patients Hospitalized at a Large US Academic Medical Center

et al. 2020

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“…In the present study, we illustrated the work ow that we used to triage the gynecologic patients with or without a need for emergency surgery regarding to potential COVID-19. In our triage system, the hospital quarantine wards and the buffering rooms at gynecologic department are critical to cut off the transmission pathways of COVID-19 without delaying the required medical care for patients.Given the possible missed COVID-19 diagnosis in the primary screening conducted in the outpatient clinic or quarantine wards due to infection window period and false negative test results [17], thestay in buffering roomsand the second round of screening tests are necessaryto protect transmission as a secondary line of defense. In addition, emerging evidence showasymptomatic SARS-CoV-2 infection In the triage system we use, the screening tests include nucleic acid test, chest CT scan, and serologic testing for viral antibodies, which can be nished within 6 hours.…”

Section: Discussionmentioning

confidence: 99%

Resumption of the Treatment for Non-COVID-19 Gynecologic Patients after Lifting Lock down: Experiences from Wuhan

Dong

Gao

Cai

et al. 2020

Preprint

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Background: To share our experiences of resumption of the treatment for gynecologic patients after lifting lockdown in a hotspot area of the Corona Virus Disease 2019 (COVID-19)pandemic.Methods: The triage process used to resume the medical activities for gynecologic patients at the Wuhan Union Hospital after a 76-day lockdown of the city is described and its effectiveness to avoid COVID-19 nosocomial transmission is shown.Results:The non-emergency patients are pre-triaged by contact history and body temperature at outpatient clinic and negative COVID-19 screening tests are required for an admissionin the buffering rooms at the gynecologic department. The buffering lastsfor at least three days for symptom monitoring and a second round of COVID-19 tests before they can be transferred to the regular gynecologic wards. For patients who need emergency surgery, the first screening should be completed at the quarantine wards after the surgery, followed by buffering at the gynecologic department. We received 19298 outpatient visits, admitted 326 patients, and performed 223 operations in the first two months after the lockdown was lifted, andno single COVID-19 case occurredin the hospitalized patients while the proportion of potentially high-risk patients with cancer and severe anemia were increased in comparison with the same period in 2019 and the latest two months before the lockdown.Conclusions:We provide an effective triage system with buffering at two levels to guarantee safe and timely treatment for non-COVID-19 gynecologic patients in a post-lockdown phase.

show abstract

“…In our triage system, the hospital quarantine wards and the buffering rooms at gynecologic department are critical to cut off the transmission pathways of COVID-19 without delaying the required medical care for patients. Given the possible missed COVID-19 diagnosis in the primary screening conducted in the outpatient clinic or quarantine wards due to infection window period and false negative test results [17], the stay in buffering rooms and the second round of screening tests are necessary to protect transmission as a secondary line of defense. In addition, emerging evidence show asymptomatic SARS-CoV-2 infection In the triage system we use, the screening tests include nucleic acid test, chest CT scan, and serologic testing for viral antibodies, which can be nished within 6 hours.…”

Section: Discussionmentioning

confidence: 99%

Resumption of the Treatment for Non-COVID-19 Gynecologic Patients after Lifting Lockdown: Experiences from Wuhan

Dong¹,

Gao²,

Cai³

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: To share our experiences of resumption of the treatment for gynecologic patients after lifting lockdown in a hotspot area of the Corona Virus Disease 2019 (COVID-19)pandemic.Methods: The triage process used to resume the medical activities for gynecologic patients at the Wuhan Union Hospital after a 76-day lockdown of the city is described and its effectiveness to avoid COVID-19 nosocomial transmission is shown.Results:The non-emergency patients are pre-triaged by contact history and body temperature at outpatient clinic and negative COVID-19 screening tests are required for an admissionin the buffering rooms at the gynecologic department. The buffering lasts for at least three days for symptom monitoring and a second round of COVID-19 tests before they can be transferred to the regular gynecologic wards. For patients who need emergency surgery, the first screening should be completed at the quarantine wards after the surgery, followed by buffering at the gynecologic department. We received 19298 outpatient visits, admitted 326 patients, and performed 223 operations in the first two months after the lockdown was lifted, and no single COVID-19 case occurred in the hospitalized patients while the proportion of potentially high-risk patients with cancer and severe anemia were increased in comparison with the same period in 2019 and the latest two months before the lockdown.Conclusions:We provide an effective triage system with buffering at two levels to guarantee safe and timely treatment fornon-COVID-19 gynecologic patients in a post-lockdown phase.

show abstract

Occurrence and Timing of Subsequent SARS-CoV-2 RT-PCR Positivity Among Initially Negative Patients

Cited by 48 publications

References 6 publications

Incidence of Nosocomial COVID-19 in Patients Hospitalized at a Large US Academic Medical Center

Incidence of Nosocomial COVID-19 in Patients Hospitalized at a Large US Academic Medical Center

Resumption of the Treatment for Non-COVID-19 Gynecologic Patients after Lifting Lock down: Experiences from Wuhan

Resumption of the Treatment for Non-COVID-19 Gynecologic Patients after Lifting Lockdown: Experiences from Wuhan

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