Occurrence and Recurrence of Attempted Suicide Among People With Epilepsy

Parkinson disease and the risk of epileptic seizures

“…A validation study conducted in the CPRD in 2004 found that PD diagnoses that were accompanied by ≥2 prescriptions for an antiparkinsonian drug were confirmed by review of medical records in 90% of cases . In a second sensitivity analysis, we applied a definition of incident epilepsy used by authors of another CPRD‐based study, where a patient was required to have at least 2 anticonvulsant prescriptions recorded within 1 month before or up to 6 months after a Read code for an epileptic seizure, epilepsy, or status epilepticus.…”

Reply to “Intriguing association of Parkinson disease and epileptic seizures”

“…Third, we conducted a sensitivity analysis in which we applied more rigorous criteria, namely those mentioned in the study by Hesdorffer et al As this sensitivity analysis yielded results closely similar to the main analysis, we are confident that our results are robust.…”

Intriguing association of Parkinson's disease and epileptic seizures

“…In a sensitivity analysis, these authors applied a definition of incident epilepsy that they used in another study with the same data set . However, that study used criteria of AED prescriptions in conjunction with diagnostic codes for epilepsy and not with codes for suspected epileptic seizures.…”