Occurrence and Characteristics of Stroke Events in the Atrial Fibrillation Follow-up Investigation of Sinus Rhythm Management (AFFIRM) Study

Sherman, David G.; Kim, S.G.; Boop, Bradley S.

doi:10.1016/j.accreview.2005.08.247

Cited by 35 publications

(42 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…62 In patients without hemophilia, no differences were found in the occurrence of stroke between high-risk patients in the rate control or sinus rhythm control arms, 63 indicating the need for antithrombotic prophylaxis even after successful cardioversion in patients at high risk. It is essential that the selection of PWHs with a high chance of successful cardioversion involves a cardiologist in the team of the specialized hemophilia treatment center.…”

Section: Cardiovascular Diseasementioning

confidence: 99%

How I treat age-related morbidities in elderly persons with hemophilia

Mannucci

Schutgens

Santagostino

et al. 2009

Blood

165

191

View full text Add to dashboard Cite

In persons with hemophilia, life expectancy is now approaching that of the general male population, at least in countries that can afford regular replacement therapy with coagulation factor concentrates. The new challenges for comprehensive treatment centers are thus to provide optimal health care for this aging population of patients, who often present not only with the comorbidities typically associated with hemophilia (arthropathy, chronic pain, blood-borne infections), but also with common age-related illnesses such as cardiovascular disease and cancer. There are no evidence-based guidelines for the management of these conditions, which often require drugs that interfere with hemostasis, enhance the bleeding tendency, and warrant more intensive replacement therapy. At the moment, elderly patients with hemophilia affected by other diseases should be managed like their age-group peers without hemophilia, provided replacement therapy is tailored to the heightened risk of bleeding associated with the need for invasive procedures and drugs that further compromise the deranged hemostasis. More detailed advice is provided on the schedules of replacement therapy needed to tackle cardiovascular diseases, such as acute coronary syndromes and nonvalvular atrial fibrillation, because these conditions will become more and more frequent challenges for the comprehensive treatment centers. (Blood. 2009;114: 5256-5263)

show abstract

Section: Cardiovascular Diseasementioning

confidence: 99%

How I treat age-related morbidities in elderly persons with hemophilia

Mannucci

Schutgens

Santagostino

et al. 2009

Blood

165

191

View full text Add to dashboard Cite

show abstract

“…The higher prevalence of paroxysmal AF in the group not receiving any antithrombotic therapy would contribute to the lower event rate in this patient group (Tables 2 and 3). 15 Second, the present analyses were post hoc in nature. This could affect the conclusion, and the data need to be interpreted cautiously.…”

Section: Study Limitationsmentioning

confidence: 99%

Accumulation of Risk Factors Increases Risk of Thromboembolic Events in Patients With Nonvalvular Atrial Fibrillation

Inoue

Nozawa

Hirai

et al. 2006

Circ J

View full text Add to dashboard Cite

“…Бессим-птомные рецидивы ФП у больных, получающих ан-тиаритмические средства, могут быть причиной тром-боэмболических осложнений после прекращения ан-тикоагуляции. В связи с этим у больных с высоким ри-ском инсульта может быть необходима антикоагулян-тная терапия независимо от выбранной стратегии ле-чения, хотя дизайн исследования AFFIRM не позволил получить ответ на этот вопрос [122]. Вторичный анализ подтверждал эту гипотезу, однако частота инсульта на фоне стратегии контроля ритма у больных, прекра-тивших прием варфарина, осталась неопределенной, поэтому необходимы дополнительные исследования для изучения этой важной проблемы.…”

Section: контроль частоты сердечных сокращений или ритмаunclassified

American College of Cardiology, American Heart Association and European Society of Cardiology (2006) Guidelines for the Management of Patients With Atrial Fibrillation

Fuster¹,

Ryden²,

Cannom³

et al. 2007

Racionalʹnaâ farmakoterapiâ v kardiologii

120

View full text Add to dashboard Cite

Отчет рабочей группы Американской коллегии кардиологов и Американской ассоциации сердца по практическим рекомендациям и комитета Европейского общества кардиологов по практическим рекомендациям Рекомендации разработаны в сотрудничестве с Европейской ассоциацией сердечного ритма и Обществом сердечного ритма Авторы (члены рабочей группы): V.

show abstract

Occurrence and Characteristics of Stroke Events in the Atrial Fibrillation Follow-up Investigation of Sinus Rhythm Management (AFFIRM) Study

Cited by 35 publications

References 16 publications

How I treat age-related morbidities in elderly persons with hemophilia

How I treat age-related morbidities in elderly persons with hemophilia

Accumulation of Risk Factors Increases Risk of Thromboembolic Events in Patients With Nonvalvular Atrial Fibrillation

American College of Cardiology, American Heart Association and European Society of Cardiology (2006) Guidelines for the Management of Patients With Atrial Fibrillation

Contact Info

Product

Resources

About