Occurrence and analytical methods of acrylamide in heat-treated foods

Zhang, Yu; Zhang, Genyi; Zhang, Ying

doi:10.1016/j.chroma.2005.03.123

Cited by 161 publications

(114 citation statements)

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“…Most of published studies used 13 C 3 -acrylamide produced by Cambridge Isotope Laboratories (Andover, MA, USA) as the internal standard (Lagalante and Felter 2004;Pittet et al 2004). Beside this, 13 C 1 -acrylamide, D 3 -acrylamide, N,N-dimethylacrylamide, methacrylamide and propionamide also have been published to be used as acrylamide internal standard (Zhang et al 2005). In the present work, 13 C 3 -labelled acrylamide was also used as the internal standard.…”

Section: Sample Size and The Use Of An Internal Standardmentioning

confidence: 99%

“…As for corresponding research in our laboratory, a detailed review paper of different analytical methods employed to understand the occurrence and determination of acrylamide in foods has recently been published (Zhang et al 2005). Incorporated in the review by Zhang et al, detailed information is collated on the sample pretreatment steps (extraction conditions, derivatization, cleanup, etc.…”

Section: Introductionmentioning

confidence: 99%

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Sensitive isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry method for the determination of acrylamide in chocolate

Ren¹,

Zhang²,

Jiao³

et al. 2006

Food Additives and Contaminants

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Isotope dilution liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-MS/MS) was applied to the quantification of acrylamide in chocolate matrixes (dark chocolate, milk chocolate, chocolate with nuts, chocolate with almonds, and chocolate with wheat best element). The method included defatting with petroleum ether, extracting with aqueous solution of 2 mol l À1 sodium chloride and clean-up by solid-phase (SPE) with OASIS HLB 6 cm 3 cartridges. Acrylamide was detected with an Atlantis dC 18 5 mm 210 Â 1.5 mm column using 10% methanol/0.1% formic acid in water as the mobile phase. The analytical method was in-house validated and good results were obtained with respect to repeatability (RSD < 3.5%) and recovery (86-93%), which fulfilled the requirements defined by European Union legislation. The acrylamide levels in chocolate were 23-537 mg kg À1. Therefore, the method was successfully used for the quantitative analysis of acrlyamide in various chocolate products.

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Section: Sample Size and The Use Of An Internal Standardmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Sensitive isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry method for the determination of acrylamide in chocolate

Ren¹,

Zhang²,

Jiao³

et al. 2006

Food Additives and Contaminants

Self Cite

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“…Gas chromatography (GC), high performance liquid chromatography (HPLC) and capillary electrophoresis (CE) have been used for determination of acrylamide in food being predisposed to acrylamide formation. The technique of HPLC equipped with mass spectrometry (MS) detector is most often used (Keramat 2001;Zhang et al 2005;Tekkeli et al 2012). Electrochemical methods are widely used in environmental and/or nutritional assessments.…”

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confidence: 99%

Determination of acrylamide in dry feedstuff for dogs and cats

Veselá

Šucman

2013

Acta Vet. Brno

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Acrylamide is considered to be an endogenous contaminant of food and feedstuff. Attention is paid to the acrylamide content in human nutrition products; however, there is lack of data about its concentrations in feedstuff. The aim of this study was to use a newly developed adsorptive stripping voltammetry procedure for determination of acrylamide concentrations in five and three different kinds of dog and cat dry feedstuff, respectively. The applied analytical procedure consists of a solvent extraction in ultrasound bath, followed by voltammetric measurement at the hanging mercury drop electrode in ammonia buffer. The accuracy of the method was verified by use of standard reference materials. The range of acrylamide concentration found in samples of dry dog and cat feedstuff ranged from 106 to 358 μg/kg, and from 66 to 269 μg/kg, respectively. The precision of analyses expressed in form of the relative standard deviations ranged between 0.6-1.7%. The voltammetric procedure appears to be a reliable, sensitive, rapid and low-cost analytical technique for the determination of acrylamide in food and feedstuff. The concentrations of acrylamide found in feedstuff were relatively moderate but it is undoubtedly necessary to monitor its concentrations in future. Dry dog feed, dry cat feed, endogenous contaminant, analysis, voltammetry

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“…For the development and application of acrylamide analysis in food, see: Rosé n & Hellenä s (2002); Hashimoto (1976); Nemoto et al (2002); Cheng et al (2006); Mizukami et al (2006), Zhang et al (2005Zhang et al ( , 2006. For halogen interactions, see : Pedireddim et al (1994).…”

Section: Related Literaturementioning

confidence: 99%

rac-2,3-Dibromopropionamide

2013

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Key indicators: single-crystal X-ray study; T = 296 K; mean (C-C) = 0.015 Å; R factor = 0.066; wR factor = 0.184; data-to-parameter ratio = 24.3.The racemic title compound, C 3 H 5 Br 2 NO, was crystallized from methanol. In the crystal, adjacent molecules are linked through N-HÁ Á ÁO hydrogen bonds, forming chains along the c-axis direction. These chains are linked through N-HÁ Á ÁO hydrogen bonds, forming an undulating two-dimensional network lying parallel to the bc plane. There are also short BrÁ Á ÁBr contacts present [3.514 (3) Å ]. Related literature

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Occurrence and analytical methods of acrylamide in heat-treated foods

Cited by 161 publications

References 92 publications

Sensitive isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry method for the determination of acrylamide in chocolate

Sensitive isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry method for the determination of acrylamide in chocolate

Determination of acrylamide in dry feedstuff for dogs and cats

rac-2,3-Dibromopropionamide

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