Occupational risk factors for prostate cancer and benign prostatic hyperplasia: a case–control study in Western Australia

Abstract

These results do not provide evidence that any of the occupational factors examined are risk factors for either prostate cancer or BPH.

An Update on Occupation and Prostate Cancer

“…Rybicki (2006) reported that petroleum workers with high polycyclic aromatic hydrocarbons (PAH) exposure, and who carry the GSTP1 Val (105) variant allele, were at increased risk of prostate cancer, especially if aged under 60 years or had a family history of the disease. A small Australian case control study (Fritschi et al, 2007) reported non-significant excess risks of prostate cancer associated with occupational exposure to oils other than mineral oil. But a recent USA study reported significant associations between petroleum and prostate cancer.…”

“…This was supported recently by Sathiakumar et al (2011), who indicated that there was no scientific basis for inferring the existence of a causal relationship between triazine exposure and the occurrence of cancer in humans. Pesticides in general have been investigated by a number of researchers (Boers et al, 2005;Fritschi et al, 2007;Strom et al, 2008;Lynch et al, 2009;Subahir et al, 2009;Xu et al, 2010;Band et al, 2011) with some studies reporting weak associations with prostate cancer and another (Mullins et al, 2012) concluding overall there are no specific environmental or occupational exposure identified that causes prostate cancer.…”

Shift work, chronodisruption and cancer?—the IARC 2007 challenge for research and prevention and 10 theses from the Cologne Colloquium 2008

“…Yet, since no occupational confounders are known (10,20), prostate cancer studies appear to offer a good opportunity with which to investigate the effects of chronodisruption.…”

Bayesian factor analysis for spatially correlated data: application to cancer incidence data in Scotland

“…Results of ecological studies suggest that prostate cancer is associated with a western lifestyle and in particular, diet that includes a high intake of fat and meat (Fritschi et al 2007;Grönberg 2003). At the same time, testis cancer is much more common in developed contest, thus the second men factor loading can be interpreted as a "social" factor, and positively associated with cancer more present in lower socioeconomic group, assuming higher values in poorer regions.…”

“…Some recent studies (Fritschi et al 2007;Grönberg 2003) shows that farming is related to prostate cancer, probably due to exposure to pesticides and fertilizers. Since farming implies working outside and having higher exposure to sunlight, this can explain the association between prostate and lips cancer.…”