Occupational rhinitis and occupational asthma: Association or progression?

Balogun, Rahmat A.; Siracusa, Andrea; Shusterman, Dennis

doi:10.1002/ajim.22819

Cited by 14 publications

(3 citation statements)

References 132 publications

(150 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nasal provocation test has been established as an international standard for evaluating occupational rhinitis 7,36,37 . It is noteworthy that in general, occupational rhinitis seems to be more common than occupational asthma 38 . To prevent more severe allergic reactions, it is important to notice early symptoms that indicate sensitization.…”

Section: Discussionmentioning

confidence: 99%

“…7,36,37 It is noteworthy that in general, occupational rhinitis seems to be more common than occupational asthma. 38 To prevent more severe allergic reactions, it is important to notice early symptoms that indicate sensitization. Fag e 4, a hevein-like antimicrobial peptide with potential cross-reactivity to latex, and Fag e 5, a vicilin-like protein.…”

Section: Case Reportsmentioning

confidence: 99%

See 1 more Smart Citation

Occupational buckwheat allergy as a cause of allergic rhinitis, asthma, contact urticaria and anaphylaxis—An emerging problem in food‐handling occupations?

Jungewelter

Airaksinen

Pesonen

2020

American J Industrial Med

View full text Add to dashboard Cite

Buckwheat is a known, though uncommon, allergen in occupational settings. It has recently gained popularity as healthy food and as an ingredient in gluten-free diets. We describe a series of six patient cases with occupational immediate allergy to buckwheat. Three cooks, two bakers, and a worker in a grocery store were occupationally exposed to buckwheat flour and developed immediate allergy to buckwheat, which was confirmed by skin prick testing and measurement of specific immunoglobulin E antibodies. Four of the patients were diagnosed with occupational asthma, four with occupational rhinitis, and two with occupational contact urticaria caused by buckwheat. Three of the six patients suffered anaphylaxis as consequence of their occupational buckwheat allergy after ingestion of food that contained buckwheat. The high rate of life-threatening reactions, together with a short exposure time to buckwheat before sensitization occurred in these cases, highlights the importance of a detailed occupational history and a high index of suspicion for occupational food allergens.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Case Reportsmentioning

confidence: 99%

Occupational buckwheat allergy as a cause of allergic rhinitis, asthma, contact urticaria and anaphylaxis—An emerging problem in food‐handling occupations?

Jungewelter

Airaksinen

Pesonen

2020

American J Industrial Med

View full text Add to dashboard Cite

show abstract

“…Nasal provocation test has been established as an international standard for evaluating occupational rhinitis . It is noteworthy that occupational rhinitis seems to be more common than occupational asthma . Two cases of occupational asthma caused by pork meat confirmed by specific inhalation challenge test with nebulized pork meat antigen or monitoring FEV 1 at work have previously been reported .…”

Section: Discussionmentioning

confidence: 99%

Occupational rhinitis, asthma, and contact urticaria from IgE‐mediated allergy to pork

Jungewelter

Airaksinen

Pesonen

2018

American J Industrial Med

View full text Add to dashboard Cite

We describe four cases of slaughterhouse workers with occupational immediate allergy to raw pork allergens, confirmed by positive skin prick testing and specific immunoglobulin E (IgE) antibodies. Our first patient was diagnosed with occupational asthma from raw pork allergens. Two patients were diagnosed with occupational rhinitis caused by raw pork allergens, which was confirmed by a nasal provocation test. One of these also had occupational contact urticaria caused by raw pork meat. We were unable to diagnose an occupational respiratory or skin disease in the fourth patient, despite signs of immediate sensitization to raw pork meat from occupational exposure. Based on proper diagnoses, measures to prevent allergen exposure were taken, which led to the improvement of symptoms in these four patients. The present patient cases highlight the importance of recognition of early signs of occupational allergy and identification of causative allergens in order to allow avoidance of allergens, with the aim of preventing persistence and worsening of symptoms.

show abstract

Immunotoxicology in Industrial Hygiene and Occupational Exposures

2023

View full text Add to dashboard Cite

Immunotoxicology is the study of drugs and chemicals that produce adverse effects on the immune system. Adverse immune effects include suppression, leading to compromised ability to fight infections, or enhancement, which could be involved in hypersensitivity (allergy) or autoimmunity. It has been appreciated for hundreds of years that diseases are associated with various occupations, such as respiratory diseases in those working with grains, coal, metals, or animals. We now understand that many of these occupational diseases are the result of an unregulated immune response to a specific agent. Similarly, occupational exposures to various chemicals can produce dermatitis, again due in part to unregulated immune responses in the skin. Additionally, occupational chemical exposures have been demonstrated to induce immune suppression. This chapter provides an overview of the immune system, a synopsis of standard assays to evaluate immunotoxic potential of occupational chemicals, and descriptions of effects of several occupational immunotoxicants with a focus on human exposures and doses. Consideration is given to current data gaps and potential use of novel technologies to more precisely define effects and mechanisms of occupational immunotoxicants.

show abstract

Occupational rhinitis and occupational asthma: Association or progression?

Cited by 14 publications

References 132 publications

Occupational buckwheat allergy as a cause of allergic rhinitis, asthma, contact urticaria and anaphylaxis—An emerging problem in food‐handling occupations?

Occupational buckwheat allergy as a cause of allergic rhinitis, asthma, contact urticaria and anaphylaxis—An emerging problem in food‐handling occupations?

Occupational rhinitis, asthma, and contact urticaria from IgE‐mediated allergy to pork

Immunotoxicology in Industrial Hygiene and Occupational Exposures

Contact Info

Product

Resources

About