Occupational Leucoderma From Rubber Dust and Debris

Irish Dermatological Society.

“…Oliver, SchwartzSt Warren (1939) were the first to report areas of depigmentation developing after contact with rubber containing the anti-oxidant monobenzykthcr of hydroquinonc. Zakon & Goldberg (1951) reported nine cases of leukoderma in white workers who came in contact with dust and debris containing this anti-oxidant. Spencer (1962) pointed out that monobenzylether of hydroquinone was equally effective as a depigmentingagent in concentrations of 1,4, 7, and 10"" and that inflammatory reactions generally precede depigmentation.…”