2021
DOI: 10.1080/20905068.2021.1926172
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Occupational formaldehyde exposure linked to increased systemic health impairments and counteracting beneficial effects of selected antioxidants

Abstract: Background: Formaldehyde (FA) is a sensitizing agent that can produce an effective immune system response upon initial exposure. FA that can be used in many industries, medical and anatomical facilities, mainly cadaver-based gross anatomy laboratories, represent a risk to occupational health of professionals and students. The majority of FA exposures occur through inhalation, dermal, and eye contact. FA-induced effects are attributed to site-specific and dosedependent health impairments in many organs and orga… Show more

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Cited by 8 publications
(7 citation statements)
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“…The oxidation of methane can and does produce a wide range of carbon-containing products such as methanol, formic acid, formaldehyde, carbon monoxide, as well as CO 2 . While methanol is commonly the desired product industrially due to its value as a potential liquid fuel and versatile chemical feedstock [29], its reactivity is limited at ambient temperature and pressures. Alternatively, formaldehyde is a flexible chemical reagent, capable of homopolymerization [30] and condensation with alcohols and amines to form solid materials and hydrogels even at ambient temperatures [31,32].…”
Section: Discussion Of Chemistrymentioning
confidence: 99%
“…The oxidation of methane can and does produce a wide range of carbon-containing products such as methanol, formic acid, formaldehyde, carbon monoxide, as well as CO 2 . While methanol is commonly the desired product industrially due to its value as a potential liquid fuel and versatile chemical feedstock [29], its reactivity is limited at ambient temperature and pressures. Alternatively, formaldehyde is a flexible chemical reagent, capable of homopolymerization [30] and condensation with alcohols and amines to form solid materials and hydrogels even at ambient temperatures [31,32].…”
Section: Discussion Of Chemistrymentioning
confidence: 99%
“…Acrylamide is genotoxic and can be a probable carcinogen according to IARC (International Agency for Research on Cancer), its intake affects the central nervous system, and dermal exposure leads to skin peeling, while dietary ingestion results in ovarian cancer (Li et al, 2021). Formaldehyde is a known carcinogen enters the body through eye contact, inhalation or via skin, its exposure causes headaches, anosmia, cough, sore throat, chest pain, breathing issues, nose-bleeding, nausea, appetite loss, irritation in the eyes, skin, and throat, vomiting and confusion, while long-term exposure results in contact dermatitis, heart disease, cancer and asthma in children (Asare-Donkor et al, 2020; Yang et al, 2020; Tesfaye et al, 2021). Tetrachloroethylene exposure damages the kidney and produces respiratory irritation, several neurological effects like headache and coma, liver injury, unconsciousness, loss of color vision, developmental effects including growth retardation, menstrual disorder, spontaneous abortions, and some birth defects are reported.…”
Section: Introductionmentioning
confidence: 99%
“…A colorless, toxic, potentially carcinogenic, watersoluble gas, with the formula CH 2 O, having a suffocating odor, usually derived from methyl alcohol by oxidation: used chiefly in aqueous solution, as a disinfectant and preservative, and in the manufacture of various resins and plastics. The toxic effects of formaldehyde and formalin were described in literature such as bronchitis, pneumonia, gastritis, myositis [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. The concept of health security corresponds to the control of risks that can alter the state of human health.…”
Section: Introductionmentioning
confidence: 99%