Occupational exposure to textile dust and lung cancer risk: Results from the ICARE Study

Khedher, Soumaya Ben; Neri, Monica; Guida, Florence; Matrat, M.; Cénée, Sylvie; Sanchez, Marie; Radoï, Loredana; Menvielle, Gwenn; Marrer, Émilie; Luce, Danièle; Stücker, Isabelle

doi:10.1002/ajim.22799

Cited by 8 publications

(9 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The assessment of occupational exposure to organic solvents, metals, other industrial chemicals, and pesticides was based on the Geoparkinson questionnaire, which was used in a previous European study on exposures in Parkinson’s disease (17). In addition, the evaluation of exposure to textile fibers was based on the questionnaire used in the ICARE study, which investigated this type of exposure in patients with lung cancer (18).…”

Section: Methodsmentioning

confidence: 99%

Occupational Exposures and Smoking in Eosinophilic Granulomatosis With Polyangiitis: A Case–Control Study

Maritati

Peyronel

Fenaroli

et al. 2021

Arthritis & Rheumatology

View full text Add to dashboard Cite

Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis. Environmental agents and occupational exposures may confer susceptibility to EGPA, but data are scarce. This study was undertaken to investigate the association between occupational exposures (e.g., silica, farming, asbestos, and organic solvents) and other environmental agents (e.g., smoking) and the risk of EGPA. Methods Patients with newly diagnosed EGPA (n = 111) and general population controls (n = 333) who were matched for age, sex, and geographic area of origin were recruited at a national referral center for EGPA. Exposures were assessed using a dedicated questionnaire administered by a specialist in occupational medicine, under blinded conditions. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated. Results Exposures to silica (OR 2.79 [95% CI 1.55–5.01], P = 0.001), organic solvents (OR 3.19 [95% CI 1.91–5.34], P < 0.001), and farming (OR 2.71 [95% CI 1.71–4.29], P < 0.001) were associated with an increased risk of EGPA. Co‐exposure to silica and farming yielded an OR of 9.12 (95% CI 3.06–27.19, P < 0.001), suggesting a multiplicative effect between these 2 exposures. Smoking (current and former smokers combined) was significantly less frequent among patients with EGPA compared to controls (OR 0.49 [95% CI 0.29–0.70], P < 0.001). The pack‐year index was also lower among patients with EGPA (OR 0.96 [95% CI 0.94–0.98], P < 0.001). The association of silica and farming was primarily aligned with ANCA‐positive EGPA, while the association of smoking status and organic solvents was primarily aligned with ANCA‐negative EGPA. Conclusion The environment can influence susceptibility to EGPA. Exposure to silica, farming, or organic solvents is associated with an increased risk of EGPA, while smoking is associated with a lower risk. These exposures seem to have distinct effects on different EGPA subsets.

show abstract

Section: Methodsmentioning

confidence: 99%

Occupational Exposures and Smoking in Eosinophilic Granulomatosis With Polyangiitis: A Case–Control Study

Maritati

Peyronel

Fenaroli

et al. 2021

Arthritis & Rheumatology

View full text Add to dashboard Cite

show abstract

“…Figure 2 shows the geographical distribution of studies worldwide. Eight studies were conducted in France (21)(22)(23)(24)(25)(26)(27)(28) and Canada (29)(30)(31)(32)(33)(34)(35)(36). There were also 4 papers in Germany (37)(38)(39)(40), and 3 in Finland (41)(42)(43).…”

Section: The Geographical Diversity Of Studies Conducted Worldwidementioning

confidence: 99%

“…Wood dust and/or formaldehyde (41), arsenic and/or quartz (38), textile dust and/or cotton fibers (24), benzene and/or gasoline (25), iron oxides (21), ethylene oxide (64), lead (35), leather dust ( 22) chlorinated hydrocarbon solvents (43) vinyl chloride, acrylonitrile and/or styrene (57), and oil mist (21) were examined in a separate study. A study also examined the effects of co-exposure to benzene, toluene, and xylene (BTX) (29).…”

Section: The Types Of Occupational Carcinogensmentioning

confidence: 99%

Scoping Review of 5 Common Occupational Cancers and Their Related Exposures

Naghibzadeh‐Tahami

Khosravi

Es'haghi

et al. 2022

Med. J. Islam. Republ. Iran

View full text Add to dashboard Cite

Background: Occupational cancers can be avoided by removing dangerous chemicals from the workplace or limiting occupational exposure. Approximately, 10 major risk factors account for 85% of all occupational cancers. This scoping review study aimed to determine the most important chemical carcinogens related to 5 known occupational cancers.Methods: In this scoping review, we followed Arksey and O'Malley's 5-step framework. Four databases (PubMed, Web of Science, Google Scholar, Scopus) were systematically reviewed for relevant published papers from January 2000 to September 2021. Studies were included in this scoping review, which examined the effect of carcinogenic (definite and probable) chemical exposures on 5 known occupational cancers (lung, bladder, laryngeal, leukemia, and liver). We reported the types of occupational carcinogens, the geographical diversity of studies, extraction of relative risks (RRs), hazard ratios (HRs), or odds ratios (ORs), and identified gaps in the existing literature.Results: The highest number of studies was related to lung cancer (LC) (n = 26), bladder cancer (BC) (n = 11), laryngeal cancer (LaC) (n = 8), leukemia (LeC) (n = 3), and primary liver cancer (PLC) (n = 2), respectively. Most studies were performed in France and Canada (n = 8), Germany (n = 4), Finland (n = 3), Netherlands (n = 2), and Finland (n = 2), respectively. Furthermore, the most common occupational chemical carcinogens associated with the 5 known occupational cancers were asbestos, benzene, crystalline silica, polycyclic aromatic hydrocarbons (PAH), and diesel motor exhausts (DME).Conclusion: Although the attributable risk of occupational cancers in developing countries is much higher, a small proportion of studies were performed in these countries.

show abstract

“…Studies among home-based garment workers in Thailand also found that exposure to garment dust was significantly correlated with respiratory symptoms (Chumchai Pornlert et al, 2014). Additionally, cotton dust exposure has been linked to decreased pulmonary function and increased cancer risk (McElvenny et al, 2011;Paulin & Hansel, 2016;Ali et al, 2018;Ben Khedher et al, 2018). Furthermore, long-term exposure to textile dust has been associated with chronic obstructive pulmonary disease (Lai & Christiani, 2013).…”

Section: Introductionmentioning

confidence: 99%

Relationship of Respirable Dust Exposure to Pulmonary Function among Informal-sector Weavers using Indigo-dyed Cotton

Kammoolkon¹,

Taneepanichskul²,

Taneepanichskul³

2021

CMUJNS

View full text Add to dashboard Cite

Informal-sector weavers using indigo-dyed cotton are occupationally exposed to respirable dust which may contain contaminants from chemicals used for pH adjustment in the natural indigo fermentation process. The major health problems associated with respirable dust induce pulmonary function impairment and respiratory disease. However, there have been few studies into the respiratory problems of informal-sector weavers in Thailand. This study investigated the link between occupational respirable dust exposure and pulmonary function among weavers using indigo-dyed cotton in Thailand. A cross-sectional study was conducted of 147 weavers located in Sakon Nakhon province. Respiratory dust (RD) samples were collected from the immediate breathing zone of all weavers. Lung function was measured using a portable spirometer operated by a trained physician and the spirometric results were examined by a pulmonologist before reporting. Most participants were female (98.6%) and the median reported interquartile age (IQR) was 58 (50–62.75) years. Average predicted values for FVC, FEV1 and FEV1/FVC were 92.9% (±20.7), 96.7% (±17.9) and 88.3% (±10.8). Of the respiratory function patterns of the 147 weavers, 20 (13.6%) were restrictive, 11 (7.5%) were obstructive and 1 (0.7%) was combined. The average RD concentration (mean ± SD) was 47.9 ± 28.3 μg/m3. Multivariate linear regression models showed an increase of 1 μg/m3 in RD exposure was associated with a 0.179% lower level of FEV1 (95% confidence interval (CI) -0.278 to -0.080) and a 0.068 % lower level of FEV1/FVC (95% CI -0.128 to -0.008). Our findings suggested that exposure to respirable dust might impair pulmonary function in informal-sector cotton weavers. Keywords: Indigo-dyed Cotton, Informal-sector Weavers, Occupational Exposure, Pulmonary function, Respirable Dust

show abstract

Occupational exposure to textile dust and lung cancer risk: Results from the ICARE Study

Abstract: Our results provide some evidence of a decreased risk of lung cancer associated with exposure to textile dust, particularly cotton.

Cited by 8 publications

References 32 publications

Occupational Exposures and Smoking in Eosinophilic Granulomatosis With Polyangiitis: A Case–Control Study

Occupational Exposures and Smoking in Eosinophilic Granulomatosis With Polyangiitis: A Case–Control Study

Scoping Review of 5 Common Occupational Cancers and Their Related Exposures

Relationship of Respirable Dust Exposure to Pulmonary Function among Informal-sector Weavers using Indigo-dyed Cotton

Contact Info

Product

Resources

About