Occupational exposure to coal and risk of multiple health outcomes: A case report

Abstract

Occupational cutaneous squamous-cell carcinoma has an increased incidence, but rarely suspected. When located in an uncovered skin area, it is closely linked to polycyclic aromatic hydrocarbons exposure. However, single pulmonary anthracosis nodule is rarely described in the literature. The association of both diseases due to the same exposure remains uncommon.

The aryl hydrocarbon receptor (AhR) activation mediates benzo(a)pyrene‐induced overexpression of AQP3 and Notch1 in HaCaT cells

“…Early investigations have shown that dermal exposure to PAHs is linked to several skin illnesses, such as acne, pigmentary diseases, aging, and cancer (Hakim et al, 2022). Nevertheless, the specific action mechanisms by which these chemicals (PAHs) exert their toxic effect on the skin are still uncertain.…”