Occupational Exposure Associated with Reproductive Dysfunction

Kumar, Sunil

doi:10.1539/joh.46.1

Cited by 168 publications

(128 citation statements)

References 134 publications

Supporting

Mentioning

121

Contrasting

Unclassified

Order By: Relevance

“…These findings are in line with previous reports [14,44] in which individuals that were regularly exposed to carbamates and endosulfan reported reproductive and erectile dysfunction. In addition, Burnett [45] in his review reports increased erectile dysfunction and loss of libido in men exposed to a variety pesticides [46,47].…”

Section: Discussionsupporting

confidence: 94%

Self-reported Health Effects among Short and Long-term Pesticide Sprayers in Arusha, Northern Tanzania: A cross Sectional Study

Manyilizu¹,

Mdegela²,

Kazwala³

et al. 2015

Occup Med Health Aff

View full text Add to dashboard Cite

There is also circumstantial evidence on the association of exposure to pesticides with chronic diseases like respiratory problems, dermal disorders, cardiovascular disease, nephropathies, chronic fatigue syndrome and aging [1]. Since health-workers are not adequately trained to identify adverse effects of pesticides [22,23] and because of the Abstract Background: The aim of the present study was to assess whether long-term exposure to pesticides is associated with adverse health effects in professional pesticide sprayers. Methods:The study was conducted in Lake Eyasi Basin and Ngarenanyuki in Arusha region, during the dry season in September-October 2013. In a cross-sectional study, 97 short-term exposed men with at most three months as professional sprayers were compared with 60 long-term exposed men with experience of at least five years as professional sprayers. The study participants were aged 18-30 years, drawn from the same source population and interviewed using semi structured questionnaire. The questions focused on spraying procedures and on present and recurrent medical history including presence of selected six known pesticide induced health conditions. Results:Organophosphates, carbamates, dithiocarbamates and pyrethroids were the most applied insecticides but also organochlorine fungicides and endosulfan were frequently applied. The majority of the sprayers reported unsafe pesticide use. Mean pesticide uses in litres, spray frequency per crop and per week were 637, and 1.3 respectively for about 270 days a year. Respiratory disease symptoms were the most frequently reported (46/157; 29.3%) followed by skin (27/157; 17.2%), and sight (24/157; 15.3%). When adjusted for age and other predictors, long-term exposed sprayers had significantly higher self-reported occurrences of peripheral neuropathy (OR=7.7, CI95%: 1.045-56.728, p=0.045) and respiratory disorders (OR=0.2, CI95%: 0.067-0.501, p=0.001) compared with short-term exposed. Furthermore, 10 sprayers, all long-term exposed reported poor libido and erection problems. Conclusions: These findings document lack of safety knowledge, safe pesticide management and the implementation of protective measures as well as suggesting that long-term exposure to pesticides increase the risk of experience disease conditions compared to short-term exposure.

show abstract

Section: Discussionsupporting

confidence: 94%

Self-reported Health Effects among Short and Long-term Pesticide Sprayers in Arusha, Northern Tanzania: A cross Sectional Study

Manyilizu¹,

Mdegela²,

Kazwala³

et al. 2015

Occup Med Health Aff

View full text Add to dashboard Cite

show abstract

“…However, the knowledge existing today regarding the influence of chemical, physical and emotional factors on male fertility is limited. Moreover, in recent decades, the industrial world has become inundated with an ever-increasing number of chemical and physical agents whose toxicity in general, and toxicity on the male reproductive system, is very little known [10][11][12]. Therefore, the objective of this study was to examine the association between male infertility and certain occupational exposures.…”

Section: Introductionmentioning

confidence: 99%

Workplace exposures and male infertility — A case-control study

El-Helaly¹,

Awadalla²,

Mansour³

et al. 2010

International Journal of Occupational Medicine and Environmental Health

View full text Add to dashboard Cite

Objectives: This study examined the association between male infertility and certain occupational exposures. Material and Methods: A case-control study was carried out from January 2008 to February 2009; on 255 infertile men and 267 fertile men controls. Occupational exposure to certain chemical, physical and psychological workplace hazards was assessed by self-report questionnaire. General and andrological examination was conducted for all participants, however, semen analysis was done only for the infertile men cases, because the fertile men controls refused to give semen samples. Results: After adjustment of confounders, the results revealed that the following workplace exposure factors significantly increased the risk of male infertility: solvents and painting materials (OR: 3.88, 95% CI: 1.50-10.03), lead (OR: 5.43, 95% CI: 1.28-23.13), VDTs and computers (OR: 8.01, 95% CI: 4.03-15.87), shift work (OR: 3.60, 95% CI: 1.12-11.57) and work-related stress (fairly present: OR: 3.11, 95% CI: 1.85-5.24; often present: OR: 3.76, 95% CI: 1.96-7.52). Conclusion: In spite of the limitations of this study, it supports other studies that raise the attention to minimize the exposure to the workplace hazards that may affect the fertility of male workers.

show abstract

“…Some of these compounds have been recognized for their mutagenic, carcinogenic and teratogenic potential 1,2) . Many of these compounds are also known for their neurotoxic 3) , reproductive and endocrine disruptive effects 4,5) . Epidemiological studies as summarized by NIOSH 3) have shown significant increase in neurobehavioral effects in workers chronically exposed to organic solvents.…”

Section: Introductionmentioning

confidence: 99%

Neurobehavioral Effects and Hormones Profile among Spray Painters

et al. 2006

Self Cite

View full text Add to dashboard Cite

A cross-sectional study was conducted in 25 spray painters and 35 control subjects to evaluate neurobehavioral function, and thyroid and reproductive hormones profile. This study indicated higher prevalence of psychological and neurological symptoms, and clinical findings among spray painters when compared with controls. Levels of TSH were significantly (p<0.01) elevated in spray painters over the control group (3.04 ± 1.53 vs 1.88 ± 1.07 µ µ µ µ µIU/ml, mean ± SD), respectively.Two of the 25 spray painters acquired sub-clinical hypothyroidism, and one subject was detected with overt hypothyroidism. T 4 levels were significantly (p<0.05) suppressed in spray painters while T 3 was not changed significantly in both the groups. Reproductive hormones (LH, FSH, and testosterone) showed no significant changes in control and spray-painting group. However, two spray painters had abnormally high level of LH (26.43 and 12.22 IU/l; normal range 0.5-10 IU/l). These subjects were also found to have abnormally higher level of FSH (38.63 and 14.11 IU/l; normal range 1.3-11.5 IU/l). An isolated higher level of FSH (39.94 IU/l) was also observed in one spray painter. No abnormality in the level of LH was observed in control group while 3 subjects from this group had abnormally high level of FSH. Testosterone levels were under the normal range (3-12 ng/ ml) in both the groups. This study might suggest that spray painters are at risk of developing neurobehavioral, thyroid and reproductive problems.

show abstract

Occupational Exposure Associated with Reproductive Dysfunction

Abstract: Occupational Exposure Associated with R e p r o d u c t i v e D y s f u n c t i o n : S u n i l K

Cited by 168 publications

References 134 publications

Self-reported Health Effects among Short and Long-term Pesticide Sprayers in Arusha, Northern Tanzania: A cross Sectional Study

Self-reported Health Effects among Short and Long-term Pesticide Sprayers in Arusha, Northern Tanzania: A cross Sectional Study

Workplace exposures and male infertility — A case-control study

Neurobehavioral Effects and Hormones Profile among Spray Painters

Contact Info

Product

Resources

About