Occupational Exposure and Thoracic Malignancies, Is There a Relationship ?

Abstract

and 300 healthy controls were enrolled in this casecontrol study. Life-long occupational history, gender, age, exposure to asbestos, comorbidities, and smoking status were collected. Results: The mean age of the 300 lung cancer cases was 60.3 ± 9.9 year (91.7% male and 8.3% female), and the mean age of healthy control group was 60.4 ± 10.5 year (95.0% male and 5.0% female). The most frequent histological types were squamous (172, 57.3%), adeno (69, 23.1%), and small cell (37, 12.3%). There was an increased risk of lung cancer occurrence among agriculture workers (OR=1.89, 95% Cl=1.17−2.98) (p=0.009). Inorganic dust exposure (OR=1.81, 95% Cl=1.0−3.25) (p=0.049) and organic dust exposure (OR=1.89, 95% Cl=1.0−3.59) (p=0.05) were found to be related with high frequency of having lung cancer. Conclusion: Workers who had occupational exposure to organic and inorganic dust, especially in the agricultural field, had higher risk of lung cancer occurrence when compared with office workers. (J Occup Health 2013; 55: 301-306)

Excess Risk of Lung Cancer Among Agriculture and Construction Workers in Indonesia

“…They identified the increased risk of lung cancer among agriculture workers (OR = 1.89, 95% Cl = 1.17−2.98) and workers exposed to inorganic dust (ceramic and pottery workers, construction, and mining) (OR = 1.81, 95% Cl = 1.0−3.25) compared to office workers. They also discovered that the elevated risk for agriculture workers was associated with pesticide use [29]. The odds ratio in our study was slightly higher than in the Baser study but comparable with a cohort study by Alavanja et al [30].…”

Lung cancer risk in relation to jobs held in a nationwide case–control study in Iran

“…In a previous study from Indonesia, an elevated OR of 3.6 (95% CI: 1.2 to 10.4) was reported among farmers (both sexes) 28. Another study carried out in Turkey observed an increased risk of lung cancer among workers in agriculture with OR of 1.9 (95% CI: 1.0 to 3.2) 34. A study among Italian female farmers, also reported an elevated OR of 1.7 (95% CI: 0.7 to 4.4) for lung cancer 35.…”

“… 28 Another study carried out in Turkey observed an increased risk of lung cancer among workers in agriculture with OR of 1.9 (95% CI: 1.0 to 3.2). 34 A study among Italian female farmers, also reported an elevated OR of 1.7 (95% CI: 0.7 to 4.4) for lung cancer. 35 The female farmers in Iran mostly live in rural areas, who likely carry out other tasks in addition to farming, for example, baking and cooking, which raise the concerns about exposure to combustion of biomass fuels.…”