Occupational dermatitis from ethylenediamine

Sensitization to ethylenediamine dihydrochloride in patients with contact dermatitis in northeastern Italy from 1996 to 2021

“…Deeply analysing the characteristics of subjects sensitised to EDD, the most frequently involved sites were primarily hands/forearms followed by the face, as parts of the body most exposed to external agents, which is in line with other studies 19,32,34,50 . However, there was no significant difference in the MOAHLFA body localizations if compared with the EDD‐negative group.…”

“…It is used as a stabiliser in rubber latex, corrosion inhibitor in antifreeze solutions and cooling fluids, epoxy curing agent, accelerator in colour development baths in photography, solvent for casein, albumin and shellac. Other industrial applications are in the preparation of electroplating and electrophoretic gels, dyes, insecticides, floor polish removers, synthetic waxes and textile lubricants 19–21 …”

“…4,18 Although rare, the allergic reactions to these EDA derivatives may result in significant morbidity. 17 Occupational CD (OCD) to EDD has been reported much more rarely than non-OCD, 16,19 despite being present in numerous industrial processes. It is used as a stabiliser in rubber latex, corrosion inhibitor in antifreeze solutions and cooling fluids, epoxy curing agent, accelerator in colour development baths in photography, solvent for casein, albumin and shellac.…”

Chromate and amine contact allergies in workers manufacturing precast concrete elements

“…Occupational cases of ethylenediamine contact allergy have been reported among workers handling epoxy systems, in which ethylenediamine and related amines are used as curing agents , and in workers exposed to ethylenediamine‐containing coolant oils and synthetic coolants . Furthermore, allergic reactions to ethylenediamine have been reported in healthcare workers handling theophylline and aminophylline . No history of exposure to ethylenediamine could be found in the ethylenediamine‐allergic workers.…”

Allergic contact dermatitis in two employees of an ethylene amine‐producing factory

“…Occupational allergic contact dermatitis caused by EDA has been described, with the cause being exposure to aminophylline, lubricants, metal polishers, detergents, floor polish removers, and epoxy resin hardeners, among other substances . One study investigated a cohort of employees of an ethylene amine‐producing factory exposed to EDA over the course of 36 years, and found that many had developed skin and/or respiratory complaints .…”