Occupational contact dermatitis from propranolol, hydralazine and bendroflumethiazide

Occupational airborne contact dermatitis from benzodiazepines and other drugs

“…Patient 4 also had reactions to β‐blocking agents, which have been reported as occupational allergens in the pharmaceutical industry, in particular propanolol and carvedilol . Allergic contact dermatitis caused by β‐blockers in eyedrops used for the treatment of glaucoma is a known entity, and, in several cases, different patterns of concomitant/subsequent contact dermatitis have been observed .…”

Allergic contact dermatitis caused by topical propranolol in a 5‐month‐old baby

“…A concern was raised regarding the possible sensitizing capacity of propranolol when used for percutaneous application (3). Although propranolol has been used since 1964, both orally and parenterally, there are no reports in the literature of allergic contact dermatitis in patients or nursing staff who come into prolonged contact with the drug, but a few studies have described allergic contact dermatitis in industrial workers involved in its production (4)(5)(6). Patch tests performed in 36 patients applying topical propranolol and in 40 family members involved in the administration of the drug gave negative results (3).…”

Dictionary of Contact Allergens: Chemical Structures, Sources and References

“…Cross-sensitivity is frequent with hydrazine, which is considered to be a potent sensitizer. Pereira F, Dias M, Pacheco FA (1996) …”