Occupational contact dermatitis due to pyritinol

Wigger‐Alberti, W.; Elsner, P.

doi:10.1111/j.1600-0536.1997.tb00047.x

Cited by 18 publications

(2 citation statements)

References 16 publications

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“…The free sulfhydryl (SH‐)group in thiol drugs may contribute to the induction of skin lesions. 2 cases have been reported (26, 27); in one of them (26), the allergic contact dermatitis developed in a nurse who had to crush Encephabol ® tablets between 2 spoons prior to administration.…”

Section: Discussionmentioning

confidence: 99%

Occupational allergic contact dermatitis from drugs in healthcare workers

Gielen

Goossens

2001

Contact Dermatitis

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Contact sensitivity to drugs administered systemically occurs mainly among healthcare workers, pharmaceutical operatives, and veterinary surgeons. Of the 14,689 patients suspected of contact allergy examined in our department from 1978 to 2001, occupational allergic contact dermatitis from drugs in healthcare workers was diagnosed in 33, the first in 1980. The most common sensitizers were antibiotics such as penicillins, cephalosporins, and aminoglycosides. They accounted altogether for 35 positive patch tests, followed by propacetamol hydrochloride, and ranitidine hydrochloride, which elicited 10 and 7 positive reactions, respectively. The aim of this report is to draw attention to the importance of occupational contact allergy to drugs in healthcare workers. By far the greatest number of the sensitized patients in this series were nurses, there being 26 nurses, 4 veterinarians, 2 pharmacists, and 1 medical doctor.

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Section: Discussionmentioning

confidence: 99%

Occupational allergic contact dermatitis from drugs in healthcare workers

Gielen

Goossens

2001

Contact Dermatitis

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“…It was originally discovered in coal tar and is now widely used in laboratories for polymer chemistry. In laboratory workers, occupational sensitization to pyridine compounds, including methyl‐ter‐pyridine, pyritinol, 4‐vinylpyridine or pyridine in the Karl Fischer reagent, has been reported (2–6).…”

Section: Commentmentioning

confidence: 99%