Occupational contact allergy to sodium cocoamphopropionate in a hand cleanser

Pesonen, Maria; Kuuliala, Outi; Aalto‐Korte, Kristiina

doi:10.1111/cod.12474

Cited by 12 publications

(4 citation statements)

References 6 publications

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“…Twelve cases of coco‐amphopropionate contact allergy were diagnosed during the 5‐year study period. They were all caused by Sensisept H34 disinfectant hand cleanser that has been extensively used especially in fast food restaurants 6 …”

Section: Resultsmentioning

confidence: 99%

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The additive value of patch testing non‐commercial test substances and patients' own products in a clinic of occupational dermatology

Aalto‐Korte

Pesonen

2022

Contact Dermatitis

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Background: Commercial patch test substances do not cover all occupational contact allergens. Workplace materials and in-house test substances are tested to complement the investigation of occupational skin disease (OSD).Objectives: To quantify the additional value of testing workplace materials and noncommercial in-house test substances in the diagnosis of OSD.Materials and Methods: Patients files of 544 patients patch tested at the Finnish Institute of Occupational Health in 2015-2019 were reviewed for occupation, diagnoses and patch test results.Results: OSD was diagnosed in 353 (64.9%) of the patients. A total of 206 (37.9%) patients had occupational allergic contact dermatitis (OACD). In 19 (3.5%) patients, the only clues to the diagnoses of OACD were positive reactions to workplace materials, and in 20 (3.7%) patients, the diagnosis of OACD was based on commercially unavailable test substances. In 167 OACD cases diagnosed by commercial test substances, additional causes were found in 17 by testing patients' own and noncommercial test substances. In 43 (7.9%) cases, positive reactions to workplace materials reinforced diagnoses based on commercial test substances. The overall additive value of testing own products was 16.7% (91 cases). Conclusion:We would have missed 39 (18.9%) of our 206 OACD cases if we had solely used commercial test substances.

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Section: Resultsmentioning

confidence: 99%

“…They were all caused by Sensisept H34 disinfectant hand cleanser that has been extensively used especially in fast food restaurants. 6 …”

Section: Resultsmentioning

confidence: 99%

The additive value of patch testing non‐commercial test substances and patients' own products in a clinic of occupational dermatology

Aalto‐Korte

Pesonen

2022

Contact Dermatitis

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“…These substances are widely used as surfactants and as foaming and cleansing agents, mainly in cosmetic products, because of their good toxicological characteristics and their mild irritation potential, for example in comparison with anionic surfactants (–). Seven cases of occupational contact allergy to sodium cocoamphopropionate in a disinfecting hand cleanser (Sensisept H34®) in Finnish and Swedish workers have been published (, ). Only a few cases of occupational contact allergy to other imidazoline‐derived amphoteric surfactants have been reported (, ).…”

Section: Discussionmentioning

confidence: 99%

Occupational contact allergy to sodium cocoamphopropionate in a skin protection cream

2018

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“…Accordingly, patch testing with patient's own material (POM) is a highly relevant, however, complex diagnostic measure with great practical importance in the diagnosis of OSD, 8 which contributes to closing the diagnostic gap and is highly important in detecting new allergens and new sources of exposure to known allergens (e.g. isobornyl acrylate (IBOA) in glucose sensors, 9 sodium cocoamphopropionate in an occupationally used skin barrier cream 10 and in occupationally used hand cleansers 11,12 or N-butyl-1,-2-benzisothiazolin-3-one in a cutting fluid). 13 The high relevance and additive value of testing POM has already been stressed in several publications over the last decades [14][15][16] ; for such patch testing, the POM must be prepared appropriately, including the selection of a suitable dilution (i.e.…”

Section: Introductionmentioning

confidence: 99%

Quality of patch testing patient's own material in patients with suspected occupational skin diseases throughout Germany: Interim results of the German Social Accident Insurance (DGUV) research project FB 317b

Symanzik,

Dicke,

Weinert

et al. 2023

Contact Dermatitis

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BackgroundDue to limited availability of commercial test preparations, patch testing patient's own material (POM) is of great importance to diagnose occupational allergic contact dermatitis.ObjectivesTo assess the quality of performance and documentation of patch testing with POM in patients with suspected occupational skin diseases (OSD) in Germany.MethodsRetrospective‐prospective analysis of protocols of patch tests with POM was conducted between 2013 and 2021 in patients with suspected OSD and submitted to statutory accident insurance institutions. Assessments were done by predefined criteria.ResultsThree thousand and four patch tests with POM from 460 patients were included. A full description of the POM was provided in 73.3% of all tests. The test concentration, test vehicle and pH value were documented in 74.3%, 70.5% and 42.2% of tests, for which the respective parameters were considered relevant. One hundred and sixty‐one positive reactions to POM were documented. In 72%, sufficient patch testing with commercial test substances was conducted to investigate the positive reaction. In 30.4%, consecutive patch testing of all ingredients of the POM was done.ConclusionsThe results not only show considerable shortcomings mainly in documentation but also to some extent performance of patch tests with POM in patients with suspected OSD in Germany.

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Occupational contact allergy to sodium cocoamphopropionate in a hand cleanser

Cited by 12 publications

References 6 publications

The additive value of patch testing non‐commercial test substances and patients' own products in a clinic of occupational dermatology

The additive value of patch testing non‐commercial test substances and patients' own products in a clinic of occupational dermatology

Occupational contact allergy to sodium cocoamphopropionate in a skin protection cream

Quality of patch testing patient's own material in patients with suspected occupational skin diseases throughout Germany: Interim results of the German Social Accident Insurance (DGUV) research project FB 317b

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