Occupational bladder cancer in New Zealand: a 1‐year review of cases notified to the New Zealand Cancer Registry

Dryson, Evan; Walls, Chris; McLean, David; Pearce, Neil

doi:10.1111/j.1445-5994.2005.00834.x

Cited by 5 publications

(6 citation statements)

References 28 publications

(81 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[1518192021] In our study, the proportion of persons with history of high risk occupations in case group was significantly more than control group with OR = 2.43 (1.37-4.33) [Table 5], this is comparable to other studies.…”

Section: Discussionsupporting

confidence: 87%

“…Compare to other cancers, bladder cancer is most strongly linked to occupational exposure to chemical toxins. [14171819] According to some studies, 21-27% of all bladder cancers in men and 11% of all bladder cancers in women are a result of work exposure. [27] This study has been performed to understand which occupations and exposures are related to bladder cancer in Iranian workers.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Occupational risk of bladder cancer among Iranian male workers

et al. 2014

View full text Add to dashboard Cite

Background:Approximately 5-10% of human cancers are thought to be caused by occupational exposure to carcinogens. Compare to other cancers, bladder cancer is most strongly linked to occupational exposure to chemical toxins. This study has been performed to understand which occupations and exposures are related to bladder cancer in Iran.Materials and Methods:This study is a case-control study which is conducted on cases with bladder cancer (160 cases) diagnosed in Baharlou hospital in 2007-2009. One hundred sixty cases without any occupational exposure were considered as controls matched for demographic characteristics. Demographic data and characteristics of occupation were compared.Results:Mean age of cases and controls were 63.7 and 64 years, respectively (P = 0.841). History of urinary tract stone had significantly difference in two groups (P = 0.039). Occupations such as bus and truck driving, road and asphalt making, mechanics, working in refinery and Petrochemical, plastic, metal manufactory, welding, and pipeline founded a higher risk for bladder cancer rather than controls.Conclusion:Our findings on Iranian workers are concurrent and compatible with findings of previous reports about occupational and environmental risk factors of bladder cancer. Although our study population was

show abstract

Section: Discussionsupporting

confidence: 87%

Section: Introductionmentioning

confidence: 99%

Occupational risk of bladder cancer among Iranian male workers

et al. 2014

View full text Add to dashboard Cite

show abstract

“…To identify these, we conducted a PubMed search from 1980 onwards for English‐language publications of studies that contained both of the key words ‘bladder cancer’ and ‘occupation’ or ‘occupational exposures’ and prepared summary tables of the positive findings. These were then reviewed by the OSH Cancer Panel4 which identified occupations and occupational exposures for which it was considered that there was evidence of a probable increased risk of bladder cancer. The final list included hairdressers, salespersons, horticultural workers, painters, metal workers, blacksmiths and toolmakers, mechanics, printing trades workers, tailors and dressmakers, operators in mining and mineral processing, metal processing, and chemical processing, rubber workers, textile workers, drivers, and building workers.…”

Section: Methodsmentioning

confidence: 99%

“…It is unlikely that New Zealand workplace conditions differ markedly from those in other developed countries in terms of their occupational cancer risk, but the type and range of industry may differ in New Zealand. In 2001, the Massey University Centre for Public Health Research and the New Zealand Department of Labor, therefore, commenced a project to evaluate occupational contributions to the development of leukemia, non‐Hodgkin's lymphoma and bladder cancer 4. The controls for the 3 studies have been pooled to provide greater precision for the control exposure prevalence estimates.…”

mentioning

confidence: 99%

Case‐control study of high risk occupations for bladder cancer in New Zealand

Dryson

Mannetje

Walls

et al. 2007

Intl Journal of Cancer

View full text Add to dashboard Cite

We conducted a nationwide case-control study of bladder cancer in adult New Zealanders to identify occupations that may contribute to the risk of bladder cancer in the New Zealand population. A total of 213 incident cases of bladder cancer (age 25-70 years) notified to the New Zealand Cancer Registry during 2003 and 2004, and 471 population controls, were interviewed face-to-face. The questionnaire collected demographic information and a full occupational history. The relative risks for bladder cancer associated with ever being employed in particular occupations and industries were calculated by unconditional logistic regression adjusting for age, sex, smoking and socio-economic status. Estimates were subsequently semi-Bayes adjusted to account for the large number of occupations and industries being considered. An elevated bladder cancer risk was observed for hairdressers (odds ratio (OR) 9.15 95% Confidence Interval (95%CI) 1.60-62.22), and sewing machinists (OR 3.07 95%CI 1.35-6.96). Significantly increased risks were not observed for several other occupations that have been reported in previous studies, including sales assistants (OR 1.03 95%CI 0.64-1.67), painters and paperhangers (OR 1.42 95%CI 0.56-3.60), sheet metal workers (OR 0.39, 95%CI 0.15-1.00), printing trades workers (OR 1.11 95%CI 0.41-3.05) and truck drivers (OR 1.36 95%CI 0.60-3.09), although the elevated odds ratios for painters, printers and truck drivers are consistent with excesses observed in other studies. Nonsignificantly increased risks were observed for tailors and dressmakers (OR 2.84 95%CI 0.62-13.05), rubber and plastics products machine operators (OR 2.82 95%CI 0.75-10.67), building workers (OR 2.15,, and female market farmers and crop growers (OR 2.05 95%CI 0.72-5.83). In conclusion, this study has confirmed that hairdressers and sewing machinists are high risk occupations for bladder cancer in New Zealand, and has identified several other occupations and industries of high bladder cancer risk that merit further study. ' 2007 Wiley-Liss, Inc.

show abstract

“…In contrast, tumors that have not invaded the muscularis propria (stage Ta, T1, and in situ carcinomas) are usually resected by organ-preserving transurethral resection and present 10-year survival rates of 70% to 85% (2). Screening high-risk groups, such as the elderly, cigarette smokers, and certain occupational groups including truck drivers, painters, and workers in the textile dye and rubber tire industries (3,4), would be predicted to lead to a higher proportion of tumors being identified at the pre -muscle-invasive stage and an overall decrease in the bladder cancer burden.…”

mentioning

confidence: 99%

Development of a Multiplex RNA Urine Test for the Detection and Stratification of Transitional Cell Carcinoma of the Bladder

Holyoake

O’Sullivan

Pollock

et al. 2008

Clinical Cancer Research

View full text Add to dashboard Cite

Purpose: New markers that enable the percentage of transitional cell carcinomas (TCC) of the bladder that are diagnosed before invasion of the bladder muscle layers to be increased would reduce the morbidity and mortality associated with this disease. The purpose of this study was to develop a simple, accurate urine test based on mRNA markers and simple gene signatures that (a) could detect TCC before muscle invasion while maintaining high specificity in patients with hematuria or urinary tract infections and (b) identify patients most likely to have grade 3 or stage zT1disease. Experimental Design: RNA markers with high overexpression in stage Ta tumors and/or T1 to T4 tumors but low expression in blood or inflammatory cells were characterized by quantitative reverse transcription-PCR using 2 mL of voided urine from 75 TCC patients and 77 control patients with other urological diseases. Results: A combination of the RNAs CDC2, MDK, IGFBP5, and HOXA13 detected 48%, 90%, and 100% of stage Ta, T1, and >T1 TCCs, respectively, at a specificity of 85%. Detection of Ta tumors increased to 60% for primary (non-recurrent) Ta tumors and 76% forTa tumors z1cm in diameter. Test specificity was 80% for the 20 control patients with urinary tract infections. The combination of CDC2 and HOXA13 distinguished between grade 1 to 2 TCCs and grade 3 or stage zT1TCCs with f80% specificity and sensitivity. Conclusions: Simple gene expression signatures can be used as urine markers for the accurate detection and characterization of bladder cancer.There are f360,000 new cases of bladder cancer worldwide annually and f145,000 deaths from the disease (1). About 30% of tumors have invaded into or beyond the muscularis propria at the time of diagnosis. Patients with these muscleinvasive tumors (stages T2-T4) have 10-year recurrence-free survival rates ranging from >80% for organ-confined tumors to f30% for tumors with regional lymph node metastases (2). Muscle-invasive tumors are generally treated by radical cystectomy with bilateral pelvic lymph node dissection followed by urinary diversion. In contrast, tumors that have not invaded the muscularis propria (stage Ta, T1, and in situ carcinomas) are usually resected by organ-preserving transurethral resection and present 10-year survival rates of 70% to 85% (2). Screening high-risk groups, such as the elderly, cigarette smokers, and certain occupational groups including truck drivers, painters, and workers in the textile dye and rubber tire industries (3, 4), would be predicted to lead to a higher proportion of tumors being identified at the pre -muscle-invasive stage and an overall decrease in the bladder cancer burden.Recent studies using high-throughput microarray analysis have shown that mRNA expression profiles are a powerful method for discriminating between bladder tumors and normal urothelium and defining subgroups of bladder tumors (5-8). The informativeness of these expression profiles and the high frequency of tumor cell exfoliation into urine have raised the prospect of...

show abstract

Occupational bladder cancer in New Zealand: a 1‐year review of cases notified to the New Zealand Cancer Registry

Abstract: The percentage of cases considered to be of occupational origin is similar to that reported in Europe and the United States, indicating that occupational cancer is a major occupational health problem in New Zealand as it is in other parts of the world.

Cited by 5 publications

References 28 publications

Occupational risk of bladder cancer among Iranian male workers

Occupational risk of bladder cancer among Iranian male workers

Case‐control study of high risk occupations for bladder cancer in New Zealand

Development of a Multiplex RNA Urine Test for the Detection and Stratification of Transitional Cell Carcinoma of the Bladder

Contact Info

Product

Resources

About