Occupational allergic contact dermatitis caused by nalmefene

Corso, Roberto; White, Ian R.; McFadden, John; Ferguson, Felicity J.

doi:10.1111/cod.13799

Cited by 2 publications

(1 citation statement)

References 7 publications

(10 reference statements)

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“…Two new pharmaceutical sources of OACD were recently reported in pharmaceutical workers: piperamido nitrotoluene, an intermediate used to manufacture imatinib, and nalmefene hydrochloride, a selective opioid receptor ligand used in the management of opioid overdose [36,37].…”

Section: Pharmaceuticalsmentioning

confidence: 99%

New causes of occupational allergic contact dermatitis

Clynick,

Holness

2023

Current Opinion in Allergy &Amp; Clinical Immunology

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Purpose of review Occupational allergic contact dermatitis (OACD) is an important work-related skin disease. Information about the causative agents comes from many sources, including patch test databases, registries, case series and case reports. This review summarizes new information about common causative allergens and diagnosis. Recent findings Common causes of OACD include rubber components, epoxies and preservatives. New exposure sources for these allergens continue to be described. Often these exposure sources are related to the changing world around us, such as allergens related to smartphones and technology, and personal protective equipment-related exposures during the COVID-19 pandemic. New allergens are also being described, some of which are related to known allergens (e.g. a new epoxy or acrylate component). Accurate diagnosis is critical to effective management of OACD, which may include removing the worker from exposure to the causative allergen. Safety data sheets may not contain complete information and patch testing with specialized series of allergens and workplace materials may be necessary. Summary This review provides current evidence about causes of OACD and important aspects of diagnosis. This is important for clinical practice to ensure cases of OACD are not missed.

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Section: Pharmaceuticalsmentioning

confidence: 99%