“…The exposure was measured in a consistent and reliable way in all cohort studies 10,16,167,169,170,[181][182][183][184] (Table 3.1, Questions 2 and 3). In seven studies 10,16,167,170,[182][183][184] , it was clear if confounding factors had been identified (Table 3.1, Question 4), with five 10,167,170,183,184 explaining how they dealt with these confounding factors (Table 3.1, Question 5), however the studies did not adjust effect estimates for the stated confounding factors. Participants in all the studies 10,16,167,169,170,[181][182][183][184] were free of the outcome at the beginning of the study (Table 3.1, Question 6).…”