Occult Nipple Involvement in Breast Cancer: Clinicopathologic Findings in 316 Consecutive Mastectomy Specimens

Abstract

Nipple-sparing mastectomy may be suitable for selected cases of breast carcinoma with low probability of nipple involvement by carcinoma and prophylactic procedures. A retroareolar en-face margin may be used to test for occult involvement in patients undergoing nipple-sparing mastectomy.

A Histopathological Study on Invasive Ductal Carcinoma Breast with Respect to ER/PR Status and Mast Cell Distribution

“…In the present study it was seen that majority of the cases had tumorsize between 2 cm to 5 cm category which was comparable with the observations made by Rojananin et al 11 and Tan PH et al 12 . However, Baxter et al 6 found that predominant tumours size was less than 2 cm.…”

The management of ductal intraepithelial neoplasia (DIN): open controversies and guidelines of the Istituto Europeo di Oncologia (IEO), Milan, Italy

“…In some institutions, such as the IEO in Milan, the NAC-sparing mastectomy is associated with IORT (so-called E [1]LIOT, one shot of 16 Gy) to the NAC [96]. In other centres, it is performed without IORT [97][98].…”

Acellular Dermal Matrix for Optimizing Outcomes in Implant-Based Breast Reconstruction: Primary and Revisionary Procedures

“…Patients with evidence of direct nipple involvement of tumor, Paget's disease, inflammatory breast cancer, tumor size > 3 cm, or tumor < 2 cm from nipple center may not be suitable candidates for NASM because of an increased risk of local tumor recurrence (Brachtel et al, 2009;Cunnick & Mokbel, 2006). Following NASM, the quality of the preserved skin is an important consideration for direct-to-implant reconstruction because extremely thin skin or compromised skin increases the risk of ischemia and skin necrosis which can eventually lead to implant loss (Woerdeman et al, 2006).…”