Occult Lung Cancer–Associated Autoimmune Encephalitis Presenting as Acute Psychosis
Shelly K McCarter,
K Robert Shen,
Mark E Wylam
Abstract:During deployment, a 52-year-old male developed acute behavioral changes. Though initially considered to have PTSD and related agitation and confusional state, his evaluation was consistent with acute encephalopathy. Magnetic resonance imaging of the brain showed T2 hyperintensities, and CSF analysis was positive for anti-N-methyl-D-aspartate receptor antibody. A nuclear protein in testis carcinoma midline carcinoma was discovered in the lung. Immunotherapy and surgical resection led to steady improvement prio… Show more
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