2013
DOI: 10.7754/clin.lab.2012.120119
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Occult Hepatitis B Virus (HBV) Infection: a Global Challenge for Medicine

Abstract: Hepatitis B virus (HBV) is a serious risk as a disease that can be spread through blood transfusion. Occult hepatitis B infection (OBI) is defined in a patient with the presence of HBV-DNA but a lack of HBsAg in the serum and hepatocytes. OBI can be considered as a high potential risk factor for inducing post transfusion hepatitis (PTH), hepatocellular carcinoma (HCC), cirrhosis, and reactivation of the HBV. Recently, several investigations from various regions of the world have reported PTH as well as HCC and… Show more

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Cited by 5 publications
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“…The Serum HBV level is usually less than 10 4 copies/mL. A sensitive HBV-DNA PCR assay is needed to diagnose occult OBI ( Aghakhani et al, 2010 , Arababadi et al, 2011a , Asli et al, 2016 , Makvandi, 2016 , Assar et al, 2012 ). It is a vital risk factor when it comes to post-transfusion hepatitis (PTH), reactivation of HBV, cirrhosis, and hepatocellular carcinoma (HCC) ( Arababadi, 2012 , Assar et al, 2012 ).…”
Section: Signs and Symptoms Of Hbvmentioning
confidence: 99%
“…The Serum HBV level is usually less than 10 4 copies/mL. A sensitive HBV-DNA PCR assay is needed to diagnose occult OBI ( Aghakhani et al, 2010 , Arababadi et al, 2011a , Asli et al, 2016 , Makvandi, 2016 , Assar et al, 2012 ). It is a vital risk factor when it comes to post-transfusion hepatitis (PTH), reactivation of HBV, cirrhosis, and hepatocellular carcinoma (HCC) ( Arababadi, 2012 , Assar et al, 2012 ).…”
Section: Signs and Symptoms Of Hbvmentioning
confidence: 99%