Occult breast abnormalities: percutaneous preoperative needle localization.

Meyer, Jack E.; Kopans, D. B.; Stomper, Paul C.; Lindfors, Karen K.

doi:10.1148/radiology.150.2.6691085

Cited by 104 publications

(27 citation statements)

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“…Noncalcified masses represent 41â€"45% of nonpalpable breast lesions referred for biopsy [6,7]. In general,only 1â€"2% of circumscribed of the specimen was represented by lesion; the remainder of the specimen consisted of fat, blood, benign breasttissue,or skin.…”

Section: Discussionmentioning

confidence: 99%

Predictive value of specimen radiography for core needle biopsy of noncalcified breast masses.

Berg

Jaeger²,

Campassi³

et al. 1998

American Journal of Roentgenology

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OBJECTIVE. Our objectivewas to determinethe predictivevalueof specimenradiography for large core (14-gauge) needle biopsy of noncalcified breast masses. SUBJECTS AND METHODS. Eighty-four biopsiesof 83 breastmassesyielded 403specimens. Specimens showing dense material on specimen radiography were predicted to be diagnostic;specimensshowingintermediate-or low-densitymaterial were predictedto be nondiagnostic. Specimenradiographicand histopathologic findingswere correlatedfor each specimen using vital dyes to mark individual specimens. RESULTS. Of the403 specimens, 307 (76%) containeddiagnosticmaterialrepresentativeof the lesion, with a specific diagnosis achieved for 82 (99%) of 83 lesions (62 benign, 20 ma lignant). Of the 293 passescontaining dense material, 268 (9 1%) proved to be diagnostic; I 1 (18%) of 62 specimenscontainingonly low-densitymaterialprovedto be diagnostic.Of the 25 (9%) of 293 specimens containing radiographically dense but nondiagnostic material, I 8 (72%) showed focal fibrosis and had missed the lesion; 15 (83%) of 18 such specimenswere obtained in dense parenchyma. The positive predictive value of specimen radiography was I3 ( 100%) of 13 in fatty breasts; 77 (96%) of 80 in breasts with minimal scattered fibroglandular elements; 91 (94%) of 97 in heterogeneously dense breasts; and 35 (70%) of 50 in breasts with extremely dense parenchyma. Of the 16 lesions sampled stereotactically, specimen radi ography helped assessthe inadequacy of initial sampling in three (19%). In six (9%) of 68 sonographically guided biopsies, only one or two specimens could be obtained; specimen ra diographyhelpeduspredictwhethermaterialwasadequatefor diagnosis. CONCLUSION. Radiography of corespecimens obtainedfrom noncalcified breastmassesaccurately reveals the adequacy of sampling unless the breast parenchyma is extremely dense.Such immediate assessment can help ensureadequatematerial from lesions that are difficult to biopsyandcantherebyimprovethediagnostic yieldoflarge coreneedlebreastbiopsy.

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Section: Discussionmentioning

confidence: 99%

Predictive value of specimen radiography for core needle biopsy of noncalcified breast masses.

Berg

Jaeger²,

Campassi³

et al. 1998

American Journal of Roentgenology

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“…In the United States, the positive predictive value (PPV) of mammography (the number of cancers diagnosed per number of biopsies recommended) has ranged from approximately 15% to 30% [2][3][4][5][6][7]; in the European trials, it ranged from 30% [8] to 75% [9]. Some of the reasons for such discrepancies have been discussed [1 0].…”

Section: Daniel B Kopans1mentioning

confidence: 99%

The positive predictive value of mammography.

Kopans

1992

American Journal of Roentgenology

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382

164

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“…The overall biopsy positivity of 27% in our clinically heterogeneous group of women appears to be consistent with previous estimates. In other series,5'6 positive biopsy percentages ranged from 9% to 65%, with a 15% to 30% positive biopsy rate among asymptomatic women7- 16 and a 20% to 40% rate among symptomatic women.17-19 Our finding that fibrocystic disease accounted for 72% of all the benign diagnoses is similar to that of a previous study .20 It is noteworthy that the older women (who are known to be at higher risk for breast cancer) have lower rates of biopsy but a higher rate of positivity in our study. The With these data, we are able to measure the parameters of biopsy rate and biopsy positivity and how these parameters vary across subgroups of age.…”

Section: Discussionmentioning

confidence: 89%

Breast biopsy rate and positivity in Rhode Island.

Richards

Feldman²,

Smith³

et al. 1994

Am J Public Health

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Breast biopsy is a common procedure for which few age-specific, population-based data are available. We identified all women who underwent breast biopsy in Rhode Island in 1989 by reviewing the specimen logs at each of 13 pathology laboratories. Among 425,000 women aged 15-97 years, 2685 underwent breast biopsy, for an overall rate of 6/1000. The rate increased with age, peaking among 45- to 54-year-olds and then declining in women over 75. Among those biopsied, 726 were diagnosed with breast cancer, for an overall biopsy positivity of 27%. In contrast to rate, positivity increased steadily with age. These results are within the range of estimates produced by smaller group studies.

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Occult breast abnormalities: percutaneous preoperative needle localization.

Cited by 104 publications

References 0 publications

Predictive value of specimen radiography for core needle biopsy of noncalcified breast masses.

Predictive value of specimen radiography for core needle biopsy of noncalcified breast masses.

The positive predictive value of mammography.

Breast biopsy rate and positivity in Rhode Island.

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