Occlusive Colon Carcinoma: Virtual Colonoscopy in the Preoperative Evaluation of the Proximal Colon

Fenlon, Helen M.; McAneny, David; Nunes, David; Clarke, Peter D.; Ferrucci, Joseph T.

doi:10.1148/radiology.210.2.r99fe21423

Cited by 226 publications

(103 citation statements)

References 30 publications

(46 reference statements)

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“…It has been found that 1.5%-9.0% of patients with a colorectal carcinoma have a second carcinoma (59). In addition, 27%-55% of patients with a carcinoma have additional adenomatous polyps.…”

Section: Pre-operative Techniquementioning

confidence: 99%

Current Status of CT Colonography

Frentz¹,

Summers²

2006

Academic Radiology

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In 2006, over 55,000 Americans are expected to die of colorectal cancer (CRC) (1). It is estimated that there is over a 5% chance that an American will develop CRC in their lifetime and over a 2% chance that an American will die from CRC (2). Fortunately, in most cases, controlling CRC is possible with the proper screening methods and the subsequent removal of suspicious polyps, adenomas, and carcinomas. If CRC is detected at an early stage, the 5-year survival rate is 90%. Unfortunately, less than 40% of colorectal cancers are detected at an early stage. Once the cancer has developed distant metastases, the 5-year survival rate is less than 10% (2).From 1998 to 2002, the incidence rate of CRC decreased by 1.8% per year, which is believed to have occurred due to increased awareness of the importance of CRC screening and consequent polyp removal (2). However, CRC is still predicted to cause about 10% of all cancer-related deaths in the United States in 2006. Relatively accurate screening methods are available to patients, but patient participation in CRC screening continues to be low. Computed tomography colonography (CTC) is a relatively new screening technology that aims to achieve a high patient acceptance, diagnostic accuracy, and screening effectiveness thereby decreasing mortality rates due to CRC.

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Section: Pre-operative Techniquementioning

confidence: 99%

Current Status of CT Colonography

Frentz¹,

Summers²

2006

Academic Radiology

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“…(4) Evaluation of the entire colon and accurate preoperative staging are essential for the optimal treatment and surgical planning of colorectal cancers. This also helps to identify patients who may benefit from chemoradiation.…”

Section: Introductionmentioning

confidence: 99%

“…(4,10) While several studies have proven that CT colonography can be used to screen for colorectal cancer, (9)(10)(11) few studies have evaluated whether contrast-enhanced MDCT colonography (CEMDCTC) is valuable for preoperative staging of colorectal cancer. (9,11) The present study aimed to compare the accuracy of colorectal cancer staging done using CEMDCTC against that done using surgery and histopathology.…”

Section: Introductionmentioning

confidence: 99%

“…(2,3) Between 1.5% and 9.0% of patients with colorectal carcinoma have a second synchronous cancer, and 27%-55% have multiple coexistent adenomatous polyps. (4) Evaluation of the entire colon and accurate preoperative staging are essential for the optimal treatment and surgical planning of colorectal cancers. This also helps to identify patients who may benefit from chemoradiation.…”

Section: Introductionmentioning

confidence: 99%

“…(9) MDCT colonography also allows: (a) simultaneous assessment of colonic mucosal surface, depth of wall invasion, pericolic lymph nodes, surrounding structures and proximal colon in patients with occlusive carcinoma; and (b) the identification of synchronous carcinomas and/or coexisting adenomatous polyps, which could influence the treatment plan. (4,10) While several studies have proven that CT colonography can be used to screen for colorectal cancer, (9)(10)(11) few studies have evaluated whether contrast-enhanced MDCT colonography (CEMDCTC) is valuable for preoperative staging of colorectal cancer. (9,11) The present study aimed to compare the accuracy of colorectal cancer staging done using CEMDCTC against that done using surgery and histopathology.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Staging of colorectal cancer using contrast-enhanced multidetector computed tomographic colonography

Narayanan¹,

Kalra²,

Bhatia³

et al. 2014

smedj

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INTRODUCTIONColorectal cancer is the third most common cancer in both men and women.(1) The pathological stage of the cancer is the most important predictive factor of overall survival in patients with colorectal cancer.(2,3) Between 1.5% and 9.0% of patients with colorectal carcinoma have a second synchronous cancer, and 27%-55% have multiple coexistent adenomatous polyps. (4) Evaluation of the entire colon and accurate preoperative staging are essential for the optimal treatment and surgical planning of colorectal cancers. This also helps to identify patients who may benefit from chemoradiation.(5) In patients with synchronous liver metastases, studies have shown that simultaneous hepatic resection is suitable for patients with 0-3 colorectal lymph node metastases, whereas neoadjuvant chemotherapy prior to resection may be more suitable for patients with ≥ 4 colorectal lymph node metastases. (6) As the low spatial and contrast resolution of conventional computed tomography (CT) protocols does not allow detailed evaluation, CT is not recommended for colorectal cancer staging. (7,8) However, multidetector computed tomography (MDCT), an advancement of CT technology, can acquire multiple simultaneous slices in a single breath-hold. Its advantages include faster scanning time, better spatial resolution, lesser motion artefacts and volume imaging. Volume imaging allows for the acquisition of either thinner or thicker sections from the same raw data, thus improving three-dimensional reconstructions and multiplanar reformation capability. (8) In MDCT colonography, the volumetric data of the large bowel obtained via high-resolution helical CT is analysed using specialised computer software to generate endoluminal images. The advantages of MDCT colonography over conventional colonoscopy include the former's noninvasive nature (which leads to better patient compliance), the ability to visualise the entire colon (conventional colonoscopy fails in 5% of cases), the absence of blind areas, and the ability to evaluate extracolonic pathology.(9) MDCT colonography also allows: (a) simultaneous assessment of colonic mucosal surface, depth of wall invasion, pericolic lymph nodes, surrounding structures and proximal colon in patients with occlusive carcinoma; and (b) the identification of synchronous carcinomas and/or coexisting adenomatous polyps, which could influence the treatment plan. (4,10) While several studies have proven that CT colonography can be used to screen for colorectal cancer, (9)(10)(11) few studies have evaluated whether contrast-enhanced MDCT colonography (CEMDCTC) is valuable for preoperative staging of colorectal cancer. (9,11) The present study aimed to compare the accuracy of colorectal cancer staging done using CEMDCTC against that done using surgery and histopathology.

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Computed Tomographic Colonography (Virtual Colonoscopy)

Cotton¹,

Durkalski²,

Pineau³

et al. 2004

JAMA

605

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OLORECTAL CANCER IS A MAjor public health issue that has received much attention in recent years. Conventional colonoscopy is widely accepted as the best available method for detection and exclusion of precursor lesions, with the advantage that most can be removed at the same examination. 1,2 However, there is consumer resistance to colonoscopy, which may be perceived as invasive and not without risk. There is a need for simpler screening methods that would allow colonoscopy to be used more selec-Author Affiliations and Financial Disclosures are listed at the end of this article.

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Occlusive Colon Carcinoma: Virtual Colonoscopy in the Preoperative Evaluation of the Proximal Colon

Abstract: Virtual colonoscopy is a feasible and useful method for evaluating the entire colon before surgery in patients with occlusive carcinomas.

Cited by 226 publications

References 30 publications

Current Status of CT Colonography

Current Status of CT Colonography

Staging of colorectal cancer using contrast-enhanced multidetector computed tomographic colonography

Computed Tomographic Colonography (Virtual Colonoscopy)

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