Occlusion of the cornea with contact lens and anterior chamber lactate levels

Abstract

Rabbits (n = 11) were fitted with large PMMA lenses to completely occlude the cornea and the anterior chamber lactate measured. The corneal epithelium was examined by light microscopy. The time period was 12 h. The results were compared with other authors' finding. There was a similarity of findings. The levels of lactate were found to have increased and the epithelium though edematous not stripped off. An individual response appeared to be the reason for the large variation in the individual findings.

A Mathematical Model of Corneal Metabolism in the Presence of an Iris-Fixated Phakic Intraocular Lens

“…Several mathematical models 8,[13][14][15][16] and experiments [17][18][19][20][21] have been proposed, aimed at describing corneal metabolism. Taking advantage of the fact that the thickness of the cornea is much smaller than its lateral dimension, in most cases onedimensional models have been adopted in which the transport of all species across the cornea is assumed to be much larger than in the other directions.…”