OC.13.4: Thromboelastography-Guided Transfusions Reduces the use of Blood Products in Cirrhotic Patients Undergoing Invasive Endoscopic Procedures

A British Society for Haematology guideline on the assessment and management of bleeding risk prior to invasive procedures

“…TEG‐guided transfusion led to a significant reduction in blood product use without an increase in bleeding complications. This finding has been replicated with both TEG and ROTEM‐guided transfusions prior to endoscopic procedures 50,51 . Emerging evidence suggests a potential role for TEG/ROTEM in reducing transfusion support in the periprocedural management of liver disease patients, with TEG maximum amplitude being a potential predictor of bleeding 52,53 .…”

“…This finding has been replicated with both TEG and ROTEM-guided transfusions prior to endoscopic procedures. 50,51 Emerging evidence suggests a potential role for TEG/ROTEM in reducing transfusion support in the periprocedural management of liver disease patients, with TEG maximum amplitude being a potential predictor of bleeding. 52,53 However, the lack of validated thresholds to guide haemostatic management necessitates further research to validate the efficacy of global haemostasis assays in this setting.…”