OC-0387: The UK HeartSpare Study (Stage II): Multicentre evaluation of a voluntary breath-hold technique

Selection of patients with left breast cancer for deep-inspiration breath-hold radiotherapy technique: Results of a prospective study

“…In the UK HeartSpare study, in which this technique was implemented at the national level, the referral for DIBH-RT was dedicated to patients with any heart inside the 50% isodose in FB-RT planning CT with standard tangential fields. 9,21 Such an approach would exclude patients with favorable anatomy and quite good heart and LAD sparing on FB from the use of this costly and time-consuming technique. On the other hand, one may argue that in the light of the suggestions that there is no threshold of dose reduction to the heart and LAD for which a clinical benefit disappears, it is difficult to set an arbitrary, but firm, value of dose constraints that preclude patients from further dose reduction attempts.…”

Modern Radiotherapy Era in Breast Cancer

“…Addition to this, voluntary technique offers a time advantage at planning-CT and treatment setup and is preferred by patients and radiographers alike compared to using the spirometry-based device [128]. In HeartSpare II study, the VBH technique is currently being ongoing at 10 UK radiotherapy centers to confirm that the technique is applicable in a multicenter setting where presented preliminary data suggest multicenter application of VBH is found to be both actual and practicable at heart-sparing [129].…”