Obstructive Sleep Apnoea in Pakistan: A Single Tertiary Care Center Experience

Sultan, Nadia; Ajmal, Maham; Saqib, Imad-ud-din; Mobeen, Amen; Iqbal, Muhammad; Mateen, Farrukh; Naseem, Sohail; Siddiqui, Maimoona; Iftikhar, Aamir

doi:10.7759/cureus.6459

Cited by 7 publications

(6 citation statements)

References 25 publications

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“…It is important to note that our study is the first systematic assessment of the knowledge of OSA amongst the final year medical students and junior doctors from Pakistan. Our findings are confirmatory to the concerns raised by experts of sleep medicine in Pakistan 8 and further reiterates the importance of educating medical students and junior doctors about this increasingly prevalent study.…”

Section: Discussionsupporting

confidence: 86%

“…Limited data are available on the prevalence of OSA in Pakistan though a cross‐sectional survey found 10%–12.4% of population at risk of developing OSA 7 . A recent cross‐sectional study describing the characteristics of over 200 patients from a single centre in Karachi, Pakistan has revive the call for the need of trained medical professionals capable of treating increasing number of OSA patients 8 …”

Section: Introductionmentioning

confidence: 99%

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Knowledge of obstructive sleep apnoea in final year medical students and junior doctors‐a multi‐centre cross‐sectional study

Zaidi

Rehman

Shafiq³

et al. 2020

Clinical Respiratory J

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Background Sleep medicine is an under‐recognised medical specialty in Pakistan and obstructive sleep apnoea (OSA) often goes unnoticed. Final year medical students and junior doctors are the primary medical contact to elicit patient history and physical examination. We aimed to measure the current knowledge of OSA amongst the final year medical students and junior doctors at four university teaching hospitals across three large Pakistani cities. Methods Cross‐sectional survey of final year medical students and junior doctors rotating through medical wards of four university teaching hospitals were conducted during August–October 2019. The knowledge section of the OSA knowledge and attitude (OSAKA) questionnaire was used. Descriptive statistics were used to present the data with Chi‐Square test and independent samples student t‐test to compare the differences between individual items and mean scores of the participants, respectively. Results A total 282 final year medical students and 204 junior doctors completed the survey yielding a response rate of 53% for medical students and 97% for junior doctors. The knowledge of sleep apnoea was poor in both groups of participants with a mean score of 7.6 (42%) on the knowledge scale of OSAKA questionnaire. Medical students scored higher on the item related to snoring as the most prevalent symptom in OSA patients when compared to the junior doctors (χ2 = 8.92, P = 0.003). More junior doctors responded correctly about the role of uvulopalatopharyngoplasty in the management of OSA when compared to the medical students (χ2 = 5.14, P = 0.02). Differences in scores of both groups of participants on other items were small and did not reach statistical significance. Conclusion Final year medical students and junior doctors from a sample of four university teaching hospitals in three large cities of Pakistan have limited knowledge about the diagnosis and management of OSA. The observed limited knowledge of OSA may contribute towards under‐diagnosis of this increasingly prevalent medical condition.

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Section: Discussionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Knowledge of obstructive sleep apnoea in final year medical students and junior doctors‐a multi‐centre cross‐sectional study

Zaidi

Rehman

Shafiq³

et al. 2020

Clinical Respiratory J

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“…Consistently Pataka A et al 11 reported that the mean of the males was 50.7 ± 14.5 years and mean age of the females was 55.5 ± 13.2 years. In another study, Sultan N et al 12 reported that the mean age of their study subjects was 50.84 years, and males were in the majority 66%, while females were 34%. On the other hand, Khan TM et al 13 patients; average age was 58.66 year, while inconsistently they found females in majority 169 as compared to males 114, out of all study subjects.…”

Section: Discussionmentioning

confidence: 91%

Correlation between Neck Circumference and Continuous Positive Airway Pressure among Patients of Obstructive Sleep Apnea

Asad¹,

Sahito²,

Rahman³

et al. 2022

PJMHS

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Objective: To investigate the relationship between neck circumference (NC) and continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA), as well as to assess CPAP requirements based on the neck circumference. Material and methods: This study was carried out in the pulmonary, vascular, and sleep disorders department of the Dow University Hospital in Karachi. The study was done for six months of duration from January 2022 to June 2022. All of the patients who had obstructive sleep apnea (OSA), between the ages of 18 and 60 years, both genders and underwent CPAP therapy were chosen for this study. The polysomnography database was utilized in order to do an analysis on the Apnea-Hypopnea Index for the OSA. Neck circumference was measured at the neck’s middle sit in every participant. The neck circumference was correlated with the CPAP therapy. The structured study proforma was used to collect all the data. Results: A total of 181 individuals who presented with OSA were studied. Mean age of the cases were 52.86+12.26 years and mean neck circumference was 43.45+3.58 cm. Males were 58.0% and females were 42.0%. Majority of the cases 56.4% had severe OSA. There was a strong significant positive correlation between neck circumference and CPAP (r= 0.177, p-value 0.017) and significant positive correlation between neck circumference and CPAP (r= 0.366, p-value 0.001). Average of CPAP pressure was significantly high according to severity of OSA (p-0.0001). Conclusion: The neck circumference was observed to be the most reliable marker that significantly positively correlated with CPAP therapy and measurements of OSA and its severity, by AHI alone, seem to have a positive correlation with CPAP therapy. However, OSA evaluation and treatment can be measured for their responsiveness to CPAP based on their neck circumference. Keywords: OSA, NC, CPAP, Relationship

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“…8,9 A recent study concluded that obstructive sleep apnea had been a common condition in our set up and clinicians that are more expert are required to deal with the disease burden efficiently. 10 Limited local data has been available regarding relationship of left ventricular function and obstructive sleep apnea syndrome. Therefore, we planned this study to look for left ventricular systolic dysfunction and the association of various factors with this dysfunction in patients with obstructive sleep apnea syndrome.…”

Section: Introductionmentioning

confidence: 99%

Left Ventricular Systolic Dysfunction in Patients of Obstructive Sleep Apnea Syndrome

Sukhera

Mirza²,

Azam³

et al. 2023

PAFMJ

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Objective: To determine the left ventricular systolic dysfunction and the association of various factors with this dysfunction in patients with obstructive sleep apnea syndrome. Study Design: Cross-sectional study. Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi Pakistan, from Dec 2020 to May 2021. Methodology: We included the patients diagnosed with sleep apnea syndrome by a consultant pulmonologist based on a sleep study. Patients were labelled as having left ventricular systolic dysfunction if the ejection fraction was less than 40% on echocardiography. Results: Eighty patients diagnosed with sleep apnea syndrome were included in the study. The mean age of the study participants was 48.551±9.971 years. Out of 80 patients, 19(23.75%) had left ventricular systolic dysfunction on echocardiography, while 61(76.25%) had no evidence of left ventricular systolic dysfunction. With the application of relevant statistical tests, we found that patients with high body mass index and the presence of comorbid illnesses had a statistically significant relationship (p-value<0.05) with the presence of left ventricular systolic dysfunction among patients with sleep apnea syndrome. Conclusion: Considerable number of patients suffering from obstructive sleep apnea syndrome showed the presence of left ventricular systolic dysfunction on echocardiography. High Body mass index and comorbid illnesses emerged as risk factors for left ventricular systolic dysfunction in our study population.

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Obstructive Sleep Apnoea in Pakistan: A Single Tertiary Care Center Experience

Cited by 7 publications

References 25 publications

Knowledge of obstructive sleep apnoea in final year medical students and junior doctors‐a multi‐centre cross‐sectional study

Knowledge of obstructive sleep apnoea in final year medical students and junior doctors‐a multi‐centre cross‐sectional study

Correlation between Neck Circumference and Continuous Positive Airway Pressure among Patients of Obstructive Sleep Apnea

Left Ventricular Systolic Dysfunction in Patients of Obstructive Sleep Apnea Syndrome

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