Obstructive sleep apnoea in children with obesity

Kassim, Rubina; Harris, Max; Leong, Gary M.; Heussler, Helen

doi:10.1111/jpc.13009

Cited by 21 publications

(10 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[2][3][4] Children with underlying medical conditions, including obesity, craniofacial anomalies, neuromuscular disorders, and certain genetic syndromes, have higher rates of OSA. [5][6][7][8] Clinical history is poorly predictive of the diagnosis, and polysomnography is required for the diagnosis of OSA. 5,6 Pulmonary hypertension (PH), an abnormal elevation in pulmonary artery pressure, is commonly reported as a cardiovascular sequelae of OSA.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Pulmonary Hypertension in Pediatric Patients With Obstructive Sleep Apnea and a Cardiology Evaluation: A Retrospective Analysis

Burns

Hansen

Turner

et al. 2019

Journal of Clinical Sleep Medicine

View full text Add to dashboard Cite

Study Objectives: Pulmonary hypertension (PH) has been reported as a serious complication of obstructive sleep apnea (OSA) in children; however, estimated prevalence rates vary widely (zero to 85%). The purpose of this study is to determine the prevalence of PH in children with OSA and identify factors that may predict an increased PH risk in children with OSA. Methods: A retrospective review of all pediatric beneficiaries (88,058) in the San Antonio Military Health System with a diagnosis of OSA and a clinical evaluation by a pediatric cardiologist. OSA severity and nadir oxygen saturation were recorded from overnight polysomnography. Reason for referral, comorbid disorders, echocardiogram results, and cardiac diagnoses were obtained from cardiology records. Results: OSA was identified in 2,020 pediatric patients (2.3%). A pediatric cardiology consultation was reported for 296 patients with OSA. After excluding 95 patients for incorrect OSA diagnoses, incomplete data, or OSA treatment before cardiology evaluation, 163 patients were included in the final analysis. A diagnosis of PH was found in 3 patients with OSA (1.8%). Two of these patients had obesity, and all three had comorbid cardiac disorders. Conclusions: Prevalence of PH in pediatric patients with OSA is low and none of the patients with PH had severe OSA. Current guidelines recommend PH screening in patients with severe OSA, yet OSA severity may not accurately predict risk. Factors evaluated in this study did not demonstrate an increased PH risk; additional research is necessary to improve screening in pediatric patients with OSA.

show abstract

Section: Introductionmentioning

confidence: 99%

Prevalence of Pulmonary Hypertension in Pediatric Patients With Obstructive Sleep Apnea and a Cardiology Evaluation: A Retrospective Analysis

Burns

Hansen

Turner

et al. 2019

Journal of Clinical Sleep Medicine

View full text Add to dashboard Cite

show abstract

“…37 Obese ATSI children have also been found to be at a greater risk of having OSA than non-ATSI obese children. 38 However, a study on primary school children in the Northern Territory did not find a significant association between race and SRBD, with similar rates of sleep breathing problems identified in both ATSI (3%) and non-ATSI (2%) groups. 39 As a possible implication of the present findings, it has been suggested that there is a significant association between OSA and poor school performance, 40 and OSA management is associated with improved school performance.…”

Section: Discussionmentioning

confidence: 92%

The risk for paediatric obstructive sleep apnoea in rural Queensland

Fischer

Karadeniz

Flores‐Mir

et al. 2021

Australasian Orthodontic Journal

View full text Add to dashboard Cite

Background: The importance of assessing patients for paediatric obstructive sleep apnoea (OSA) cannot be more highly stressed and orthodontists may play an essential role in risk screening. The Paediatric Sleep Questionnaire (PSQ) is a validated tool to identify whether a child is at risk for paediatric OSA. Objectives: The likelihood of paediatric OSA in school-aged children residing in Far North Queensland (FNQ) will be assessed using the PSQ. Methods: Parents of children aged between 4 and 18 years were invited to participate through schools and social media messaging to complete an online PSQ questionnaire to assess their OSA risk and demographics. Results: The final sample consisted of 404 school-aged children of whom 62.5% were found to be at a high-risk for paediatric OSA. The high risk was significantly associated with males and those of overweight/obese BMI status (p < 0.001). Race and age were not significant associations (p > 0.05). Conclusions: Within the contributing sample of school-aged children in FNQ, a significant number were found to be at high-risk of paediatric OSA. Males and overweight/obese children were measured risk factors.

show abstract

“…4 and 5, Table 3). Obstructive sleep apnea is a subtype of sleep apnea syndrom that is principally associated with a narrowed upper airway that has resulted from fat accumulation accompanied with obesity or other congenital or acquired conditions (Dudley and Patel 2016;Kassim et al 2016). Because For each participant, the amount of salivation was measured for 1 min during resting and various tasting states using the indicated tastants.…”

Section: Discussionmentioning

confidence: 99%

“…This is known as oral appliance therapy (Clark et al 2000;Hosoya et al 2014;Bender 2016;Lavigne and Sessle 2016). At present, obstructive sleep apnea is principally believed to be associated with a narrowed upper airway (Dudley and Patel 2016;Kassim et al 2016). Thus, clarifying the abovementioned associations would be important to the field of sleep medicine, especially in countries with relatively short sleeping times, such as Japan.…”

Section: Introductionmentioning

confidence: 99%

Gustatory Salivation Is Associated with Body Mass Index, Daytime Sleepiness, and Snoring in Healthy Young Adults

Izumi

Hong

Iwasaki³

et al. 2016

Tohoku J. Exp. Med.

View full text Add to dashboard Cite

The taste detection system for oral fatty acid may be related to obesity. In addition, sleep is intrinsically and closely related to food intake and metabolism. However, the association of gustatory salivation with body mass index (BMI), daytime sleepiness, or sleep habits is largely unknown. Therefore, we evaluated the relationship between gustatory salivation and BMI, Epworth sleepiness scale (ESS, a daytime sleepiness scale) or sleep habits among 26 healthy young individuals (20 males and 6 females; mean age: 26.0 ± 4.3 years). We also measured the saliva flow rate (SFR) that was induced by gum-chewing or each of three prototypical tastants (acetic acid, sucrose, and NaCl). Further, the SFR was induced by fatty acid, provided as oleic acid (OA) homogenized in non-fat milk. All participants showed normal rates of salivation during resting and gum-chewing states. The increase in the SFR induced by OA, but not by each of the three tastants, was associated with BMI. Moreover, both daytime sleepiness level and frequency of snoring were associated with the increase in the SFR induced by NaCl. These results suggest that BMI is associated with salivation induced by oral fatty acid exposure. Additionally, the regulatory mechanism for the NaClinduced salivation reflex may have a relationship with impairments of the respiratory control system that are related to snoring during sleep and lead to daytime sleepiness because of insufficient sleep. Thus, measurement of gustatory salivation might contribute to the evaluation and prevention of obesity and sleeprelated breathing disorders.

show abstract

Obstructive sleep apnoea in children with obesity

Abstract: Ethnicity was a significant factor with more obese ATSI children having OSA. The significant correlation between hs-CRP with OEI is consistent with findings of previous studies. Several factors (glycosylated haemoglobin, LDL) approached significance.

Cited by 21 publications

References 46 publications

Prevalence of Pulmonary Hypertension in Pediatric Patients With Obstructive Sleep Apnea and a Cardiology Evaluation: A Retrospective Analysis

Prevalence of Pulmonary Hypertension in Pediatric Patients With Obstructive Sleep Apnea and a Cardiology Evaluation: A Retrospective Analysis

The risk for paediatric obstructive sleep apnoea in rural Queensland

Gustatory Salivation Is Associated with Body Mass Index, Daytime Sleepiness, and Snoring in Healthy Young Adults

Contact Info

Product

Resources

About