Obstructive sleep apnoea in a case of thyroglossal duct cyst carcinoma

See, A.; Chua, Dennis; Chan, Yew Meng; Goh, Christopher

doi:10.1017/s0022215112001211

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…Ninety‐eight articles met the inclusion criteria and were included in the final analysis with a total population of 164 patients. Eighty‐one case reports and 17 case series were included 4–101 . The largest case series included 18 patients, and the studies that we evaluated spanned from 1986 to 2016.…”

Section: Resultsmentioning

confidence: 99%

Thyroglossal Duct Cyst Carcinoma: A Systematic Review of Clinical Features and Outcomes

Rayess

Monk

Svider

et al. 2017

Otolaryngol.--head neck surg.

115

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Objective Although thyroglossal duct cysts (TGDCs) are relatively common, malignancies within these lesions are infrequent. As a result, there are no large-scale series describing clinical characteristics. Our objectives were to perform a systematic review of the literature evaluating patient demographics, pathology, management, and prognosis of these patients. Data Sources PubMed, Embase, Cochrane reviews, and Google Scholar were searched for relevant articles. Articles meeting inclusion criteria were reviewed for data detailing epidemiology, treatment, and outcomes. Review Methods Inclusion criteria included English-language articles with original reports on human subjects. Two investigators independently reviewed all articles for the data collected, including epidemiology, treatment, and outcomes. Results Ninety-eight articles comprising 164 patients were included in the final analysis. The mean age at presentation was 39.5 years (9-83 years); 68.3% of patients were female. In total, 73.3% of cases were found on final pathologic analysis. The most common pathology was papillary cancer (92.1%). Of the patients, 98.9% underwent a Sistrunk procedure and 61.0% underwent total thyroidectomy. There was a 4.3% recurrence rate with a mean time to recurrence of 42.1 months from initial treatment. One patient died of TGDC carcinoma, while all other patients were disease free at the time of last follow-up (mean follow-up was 46.1 months). Conclusion TGDC carcinoma is typically diagnosed on final pathology. While management encompasses a Sistrunk procedure, further consideration should be given to thyroidectomy among patients ≥45 years of age and individuals with aggressive disease. TGDC carcinoma harbors an exceedingly low rate of mortality.

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Section: Resultsmentioning

confidence: 99%

Thyroglossal Duct Cyst Carcinoma: A Systematic Review of Clinical Features and Outcomes

Rayess

Monk

Svider

et al. 2017

Otolaryngol.--head neck surg.

115

View full text Add to dashboard Cite

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“…Ultrasound examination was most common, with lesions having a nonspecific cystic appearance. Computed tomography (CT) findings reported to be of value in identifying malignancy within a TGDC, include the presence of a solid component, mural nodule, or calcifications [3,19,42,43,50,[55][56][57][58][59][60][61][62][63][64][65][66][67][68][69][70][71][72]. However, these particular imaging findings were only of assistance in a few cases [4,38,48,55].…”

Section: Discussionmentioning

confidence: 99%

Thyroglossal Duct Cyst Carcinomas in Pediatric Patients: Report of Two Cases with a Comprehensive Literature Review

Thompson

Herrera

Lau³

2017

Head and Neck Pathol

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Thyroglossal duct cyst (TGDC) carcinomas are rarely encountered in the pediatric population. The clinical behavior of these tumors in the pediatric setting is unclear and management is not well defined. Two cases of pediatric thyroglossal duct cyst carcinoma were identified in a review of all thyroglossal duct cysts diagnosed over a ten year period. These two cases were analyzed along with 57 cases of thyroglossal duct cyst carcinoma affecting patients less than 21 years of age compiled from the English literature. Fifty-nine patients (36 females, 23 males) aged 6-20 years (mean 15.0 years) were identified. All presented with an anterior midline neck mass, which was typically mobile and non-tender. The average tumor size was 2.6 cm. Histologically, all tumors were papillary thyroid carcinomas arising in a background of a thyroglossal duct cyst. The tumors exhibited a papillary, follicular, or mixed architecture with classical papillary thyroid carcinoma nuclear features. Soft tissue extension was present in 16 cases. All patients were managed surgically with a Sistrunk procedure, with additional thyroidectomy performed in 29 patients, combined with a lymph node dissection (n = 15), or a Sistrunk and lymph node dissection (n = 5). All patients were stage I at presentation, with 11 showing lymph node metastases. Postoperative radioactive iodine was employed in 20 patients. A papillary carcinoma of the thyroid gland was reported in four of the patients who had concurrent/subsequent thyroidectomies. Recurrences were reported in four patients, with distant metastases in one patient, who died of disease (13 months). Follow up data was available for 45 patients, with an overall mean follow-up of 54.5 months. All patients were alive, with the exception of one who died with disease. TGDC carcinomas in pediatric patients is associated with a good overall prognosis, best managed by Sistrunk procedure alone, with selected lymph node dissection if clinically indicated.

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Association between radiotherapy and obstructive sleep apnea in head and neck cancer patients: A systematic review and meta-analysis

et al. 2021

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Obstructive sleep apnoea in a case of thyroglossal duct cyst carcinoma

Abstract: Thyroglossal duct cyst carcinomas may present atypically, posing a diagnostic dilemma for the clinician. For patients diagnosed with obstructive sleep apnoea, it is imperative that a thorough otolaryngological examination be performed to exclude any underlying pathology.

Cited by 3 publications

References 9 publications

Thyroglossal Duct Cyst Carcinoma: A Systematic Review of Clinical Features and Outcomes

Thyroglossal Duct Cyst Carcinoma: A Systematic Review of Clinical Features and Outcomes

Thyroglossal Duct Cyst Carcinomas in Pediatric Patients: Report of Two Cases with a Comprehensive Literature Review

Association between radiotherapy and obstructive sleep apnea in head and neck cancer patients: A systematic review and meta-analysis

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