Obstructive Sleep Apnea Syndrome as a Trigger of Cardiac Arrhythmias

Martí‐Almor, Julio; Jiménez‐López, Jesús; Casteigt, Benjamin; Conejos, J.; Vallès, Ermengol; Farré, Núria; Flor, Miquel Félez

doi:10.1007/s11886-021-01445-y

Cited by 9 publications

(9 citation statements)

References 52 publications

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“…In addition to atrial arrhythmias, patients with OSA are prone to sick sinus syndrome, sino-atrial block, and tachycardia-bradycardia syndrome [ 96 ]. Among patients with OSA, bradycardia was present in 25% during the daytime and 70% during the night [ 97 ].…”

Section: Osa As a Risk Factor For Cvdmentioning

confidence: 99%

“…Finally, patients with OSA are predisposed to ventricular arrhythmias. This is thought to be related to the imbalance of sympathetic and parasympathetic tone [ 96 ]. Patients with OSA are more likely to experience sudden cardiac death overnight, which is a stark contrast from the general population, which has a nadir from midnight to 6 a.m. [ 99 ], suggesting a role of OSA in the development of ventricular arrhythmias.…”

Section: Osa As a Risk Factor For Cvdmentioning

confidence: 99%

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The Role of Sleep in Cardiovascular Disease

Jaspan,

Greenberg,

Parihar

et al. 2024

Curr Atheroscler Rep

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Purpose of Review Sleep is an important component of cardiovascular (CV) health. This review summarizes the complex relationship between sleep and CV disease (CVD). Additionally, we describe the data supporting the treatment of sleep disturbances in preventing and treating CVD. Recent Findings Recent guidelines recommend screening for obstructive sleep apnea in patients with atrial fibrillation. New data continues to demonstrate the importance of sleep quality and duration for CV health. Summary There is a complex bidirectional relationship between sleep health and CVD. Sleep disturbances have systemic effects that contribute to the development of CVD, including hypertension, coronary artery disease, heart failure, and arrhythmias. Additionally, CVD contributes to the development of sleep disturbances. However, more data are needed to support the role of screening for and treatment of sleep disorders for the prevention of CVD.

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Section: Osa As a Risk Factor For Cvdmentioning

confidence: 99%

Section: Osa As a Risk Factor For Cvdmentioning

confidence: 99%

The Role of Sleep in Cardiovascular Disease

Jaspan,

Greenberg,

Parihar

et al. 2024

Curr Atheroscler Rep

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“…The fact underlying is that, an increase in blood pressure activates the carotid sinus and aortic arch baroreceptors which inhibits the sympathetic outflow and reduces the heart rate. The opposite effect is experienced due to a decrease in blood pressure [18]. Solaro et al [19] describe the spectral properties of heart rate variability and its relation to blood pressure levels.…”

Section: Osa and Baroreflexesmentioning

confidence: 99%

An automatic screening approach for obstructive sleep apnea from photoplethysmograph using machine learning techniques

2021

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Obstructive sleep apnea (OSA), a very common sleep disorder remains as an underdiagnosed root cause for several cardiovascular and cerebrovascular diseases. In this paper, we propose an efficient and accurate system that utilizes a single sensor for effective screening of OSA using machine learning algorithms. The automatic screening system involves a photoplethysmogram (PPG) signal, a novel algorithm to detect and remove the corrupted part of the signal, a feature extraction module to extract several features from the PPG waveform and a classifier module which helps in screening for OSA. The elemental idea behind this work is that there is a characteristic relationship between the shape of the PPG waveform and the oxygen desaturation in the apnea patients. The method as described was tested on 285 subjects, inclusive of both normal and apnea patients, and the results were obtained after 10-fold-cross validation of the different machine learning techniques viz., univariate regression, multivariate regression, support vector machine and random forest. The best results in screening OSA were obtained from random forest algorithm with the highest performance (Acc: 98.0%, Sen: 98.6%, Spec: 99.3%) for all the combined features. The proposed work is an effective system for automatic screening of OSA from a single PPG sensor, thereby reducing the need for a very expensive and overnight polysomnography sleep study.

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“…It is well‐known that OSA is a cause of hypertension 5 . Several studies have emphasized that OSA is an independent risk factor for coronary heart disease, 6,7 arrhythmia, 8,9 and stroke 10,11 . Metabolic disorders, including diabetes and impaired lipid metabolism, are also associated with OSA 12,13 .…”

Section: Introductionmentioning

confidence: 99%

Association of obstructive sleep apnea with cardiometabolic diseases and cardiovascular mortality

Shi

Zhu

et al. 2023

Clinical Respiratory J

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BackgroundObstructive sleep apnea (OSA) is one of the leading respiratory disorders, increasing the risk of cardiometabolic diseases. In the study, we investigated the association between OSA and the risk of cardiometabolic diseases and all‐cause and cardiovascular mortality in adults.MethodsParticipants were enrolled in the National Health and Nutrition Examination Survey. The baseline covariates were compared between participants with and without OSA status. Multivariable logistic regression was performed to explore the association between OSA and cardiometabolic diseases, while Cox proportional regression was performed for all‐cause and cardiovascular mortality.ResultsOSA status was positively associated with higher risks of cardiometabolic diseases, including hypertension (odds ratio [OR] 1.28, 95% confidence interval [CI] 1.14–1.45; p < 0.001), diabetes (OR 1.46, 95% CI 1.22–1.76; p < 0.001), and cardiovascular diseases (OR 1.29, 95% CI 1.08–1.54; p = 0.006) after adjusting for numerous covariates. However, no associations of OSA with all‐cause or cardiovascular mortality were observed.ConclusionOSA was associated with a higher risk of hypertension, diabetes, and cardiovascular diseases, but had no significant association with all‐cause or cardiovascular mortality in adults.

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Obstructive Sleep Apnea Syndrome as a Trigger of Cardiac Arrhythmias

Cited by 9 publications

References 52 publications

The Role of Sleep in Cardiovascular Disease

The Role of Sleep in Cardiovascular Disease

An automatic screening approach for obstructive sleep apnea from photoplethysmograph using machine learning techniques

Association of obstructive sleep apnea with cardiometabolic diseases and cardiovascular mortality

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