Obstructive Sleep Apnea Syndrome and the Quality of Life

Coman, Andreea Codruta; Borzan, Cristina; Vesa, Cristian Stefan; Todea, Doina Adina

doi:10.15386/cjmed-593

Cited by 29 publications

(26 citation statements)

References 19 publications

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“…22 Another study of 50 patients, predominantly men on CPAP for OSA, showed improvement in the sleep apnea QoL index 23 24 and sleep apnea QoL index. 25 A multicenter clinical effectiveness study showed improvement in FOSQ in all domains and similar to our study showed greater improvement in patients who were PAP adherent. 26 Our study differs from the existing clinical studies because it includes a robustly large number of patients and utilizes both sleep-related and global QoL instruments.…”

Section: Discussionsupporting

confidence: 88%

Impact of Sleep-Disordered Breathing Treatment on Quality of Life Measures in a Large Clinic-Based Cohort

Walia

Thompson

Katzan

et al. 2017

Journal of Clinical Sleep Medicine

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Study Objectives: This study aims to report the effect of positive airway pressure (PAP) therapy on quality of life (QoL) measures in the clinical sleepdisordered breathing (SDB) population. Methods: We examined general QoL measures assessed by European Quality of Life-5D (EQ-5D) and sleep-specific QoL by examining Functional Outcomes of Sleep Questionnaire (FOSQ) scores before and after PAP therapy retrospectively in a clinical SDB population using paired and two-sample t tests. Age and socioeconomic status (SES) effect modification on pre-PAP QoL measures were investigated utilizing the interaction terms. Results: A total of 2,027 patients with SDB initiated PAP therapy between January 1, 2010 and December 31, 2014. The mean age of the cohort was 56.2 years (standard deviation = 13.2), with 45.8% female and 76.9% Caucasians. EQ-5D change after exclusion of those with normal QoL was 0.042 (0.152) in all patients, 0.051 (0.150) in patients who were PAP adherent by self-report, and 0.050 (0.132) in patients who were objectively PAP adherent (n = 704 of 1,011 with available objective adherence data, 69.6%). Change in FOSQ after excluding those with normal FOSQ was 1.9 (2.9) in all patients, 2.2 (2.9) in patients who were PAP adherent by self-report, and 2.3 (2.9) in patients who were objectively PAP adherent. Those with (1) worse QoL at baseline and younger age and (2) worse QoL at baseline and residing in lower SES strata had worse outcomes after PAP therapy (P < .05). Conclusions:We found consistent improvement in global and sleep-specific QoL measures after PAP therapy, hence providing evidence of PAP benefit in the clinical population and rationale for targeted efforts to optimize QoL in younger and lower SES subgroups. Keywords: age, quality of life, sleep-disordered breathing, socioeconomic status Citation: Walia HK, Thompson NR, Katzan I, Foldvary-Schaefer N, Moul DE, Mehra R. Impact of sleep-disordered breathing treatment on quality of life measures in a large clinic-based cohort.

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Section: Discussionsupporting

confidence: 88%

Impact of Sleep-Disordered Breathing Treatment on Quality of Life Measures in a Large Clinic-Based Cohort

Walia

Thompson

Katzan

et al. 2017

Journal of Clinical Sleep Medicine

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“…2,14) Sleep apnea is closely related to quality of life because it induces daytime sleepiness and depressive mood. 15,16) In our study, we found that KOSA-18 scores were significantly reduced regardless of intracapsular or extracapsular tonsillectomy. It is consistent with the previous meta-analysis study.…”

Section: Discussionsupporting

confidence: 48%

Comparison of Functional Outcomes after Powered Intracapsular Tonsillectomy with Adenoidectomy and Conventional Extracapsular Tonsillectomy with Adenoidectomy for Pediatric Obstructive Sleep Apnea

Jeon¹,

Kim²,

Bang³

et al. 2020

Korean J Otorhinolaryngol-Head Neck Surg

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Background and Objectives This study was investigated to compare the clinical outcomes and complications of powered intracapsular tonsillectomy and adenoidectomy (PITA) with those of conventional extracapsular tonsillectomy and adenoidectomy (ECTA) in treatment of pediatric obstructive sleep apnea (OSA).Subjects and Method Eighty-one children with adenotonsillar hyperplasia underwent tonsillectomy and adenoidectomy (46 PITA and 35 ECTA) from December 2016 to July 2017 for OSA. The choice of surgical procedure (PITA vs. ECTA) was determined by the number of episodes of acute tonsillitis. The quality of life measurement was performed using Korean Obstructive Sleep Apnea Survey (KOSA-18) score. Postoperative bleeding was assessed as number of revisit or readmission. Postoperative pain was evaluated by visual analog scale (VAS) at postoperative day 1, 3, and 7.Results PITA and ECTA significantly reduced KOSA-18 scores postoperatively (p＜0.01, p＜0.01, respectively) and were equally effective in pediatric OSA treatment. Postoperative bleeding was lower in the PITA group, but there was no statistical difference due to small number of cases. VAS score for postoperative pain was significantly lower in the PITA group at day 1, 3, and 7 (p=0.03, p＜0.01, and p＜0.01, respectively).Conclusion PITA is effective in pediatric OSA treatment with less morbidity, and less complications.

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“…Increased SF and decreased quality of sleep have an undesirable impact on QoL and wellbeing linked with EDS . The marked impairment of QoL in patients with OSA improved after 3 months of nCPAP treatment . Those with higher AHI and increased frequency of microarousal demonstrated better compliance and greater improvement in QoL with nCPAP therapy.…”

Section: Discussionmentioning

confidence: 98%

“…13 The marked impairment of QoL in patients with OSA improved after 3 months of nCPAP treatment. 14 Depressive symptoms have been shown to be reduced with nCPAP treatment in patients with severe strokes and sleep apnea. 15 An improvement in cognitive, visual, spatial, and verbal memory were observed after 3 months of The Health-Related QoL (HRQoL) in patients with Sleep Apnea Hypopnea Syndrome (SAHS) at the time of diagnosis was low.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of nasal continuous airway pressure therapy in patients with obstructive sleep apnea

Kandasamy

Almaghaslah

Senthilnathan

et al. 2019

Health Planning & Management

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Summary Objectives A prospective observational study was carried out with the aim of evaluating the effectiveness of nasal continuous positive airway pressure (nCPAP) therapy on the health‐related quality of life (QoL) of patients with obstructive sleep apnea (OSA). Methods The patients included in this study were those recently diagnosed with OSA (AHI > 5) and given nCPAP therapy, as well as being referred to a sleep laboratory for an assessment of their sleep disordered breathing. Prior to the start of nCPAP therapy and polysomnography evaluation, patients were asked to complete the validated Quebec sleep questionnaire (QSQ), and their baseline measurements were recorded. Results Among the study population, 14.41% (n = 31) had mild OSA with an apnea and hypopnea index of 5 to 14.9 events/h, while 26.97% (n = 58) had moderate OSA and 40% (n = 86) had severe OSA. The overall average apnea and hypopnea index of the study population was 30.24 ± 9.73 events/h; mild OSA patients had an average apnea and hypopnea index of 10.09 ± 2.65 events/h, moderate OSA patients had 21.48 ± 4.40 events/h, and severe OSA patients had 59.16 ± 22.14 events/h. A significant difference was observed between the scores before treatment and after 6 months of therapy in all domains of the QSQ QoL scores (P < 0.0001). Conclusion Nasal continuous positive airway pressure treatment improved the QoL for patients with mild, moderate, and severe sleep apnea.

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Obstructive Sleep Apnea Syndrome and the Quality of Life

Cited by 29 publications

References 19 publications

Impact of Sleep-Disordered Breathing Treatment on Quality of Life Measures in a Large Clinic-Based Cohort

Impact of Sleep-Disordered Breathing Treatment on Quality of Life Measures in a Large Clinic-Based Cohort

Comparison of Functional Outcomes after Powered Intracapsular Tonsillectomy with Adenoidectomy and Conventional Extracapsular Tonsillectomy with Adenoidectomy for Pediatric Obstructive Sleep Apnea

Effectiveness of nasal continuous airway pressure therapy in patients with obstructive sleep apnea

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