Obstructive sleep apnea in infancy: A 7‐year experience at a pediatric sleep center

Ramgopal, Sriram; Kothare, Sanjeev V.; Rana, Mandeep; Singh, Kanwaljit; Khatwa, Umakanth

doi:10.1002/ppul.22867

Cited by 40 publications

(38 citation statements)

References 44 publications

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“…In a 2014 report, Ramgopal et al 5 found that craniofacial abnormalities were a risk factor for OSA during infancy. They also found that craniofacial abnormalities was indication for PSG in 16% of their cohort, which is within range of our 2012 findings.…”

Section: Discussionmentioning

confidence: 99%

“…4 For otherwise healthy children with suspected OSA, performing outpatient PSG is considered a reasonable option for work-up; however, many children with significant medical comorbidities may undergo inpatient PSG within the first year of life. Over the past 10 years, multiple authors have reported an association between OSA and conditions such as laryngomalacia [5][6][7] and craniofacial anomalies. 5,8,9 Given that these conditions are commonly diagnosed in early infancy, one would expect that children with laryngomalacia or craniofacial anomalies and signs of sleep disordered breathing (SDB) would be more likely to undergo inpatient PSG than older, otherwise healthy children.…”

Section: Introductionmentioning

confidence: 99%

“…Over the past 10 years, multiple authors have reported an association between OSA and conditions such as laryngomalacia [5][6][7] and craniofacial anomalies. 5,8,9 Given that these conditions are commonly diagnosed in early infancy, one would expect that children with laryngomalacia or craniofacial anomalies and signs of sleep disordered breathing (SDB) would be more likely to undergo inpatient PSG than older, otherwise healthy children. Despite this, the AAP and AASM make no specific recommendations regarding the setting of PSG for these medically complex patients.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Trends in Inpatient Pediatric Polysomnography for Laryngomalacia and Craniofacial Anomalies

Tawfik

Sedaghat

Ishman

2015

Ann Otol Rhinol Laryngol

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Objective: Increasingly, laryngomalacia and craniofacial anomalies are recognized as risk factors for obstructive sleep apnea. We sought to determine whether children with these diagnoses have become more likely to undergo inpatient polysomnogram (PSG) over time and to identify evolving trends in PSG utilization. Methods: Retrospective analysis of the Kids' Inpatient Database from 2003 to 2012. Children <21 years who underwent PSG were included. Weighted comparisons of clinical/demographic characteristics of patients undergoing PSG were performed, as were associations between clinical and demographic patient characteristics and performance of inpatient PSG. Results: Between 2003 and 2012, PSG procedures decreased from 1266 to 829 (P < .001). Among children who underwent PSG, mean age decreased from 3.9 ± 5.1 to 3.1 ± 5.2 years (P = .001), and the frequency of age <1 year increased from 47.8% to 59.5% (P < .001). The frequency of laryngomalacia increased from 2.5% to 14.3% (P < .001), while the frequency of craniofacial anomalies increased from 6.2% to 19.4% (P < .001). Laryngomalacia and craniofacial anomalies were predictive of undergoing inpatient PSG in both timeframes. Conclusion: Despite decreasing PSG volumes, diagnoses of laryngomalacia and craniofacial anomalies comprised increasing fractions of children undergoing inpatient PSG between 2003 and 2012. Laryngomalacia and craniofacial anomalies were also predictive of inpatient PSG use in both timeframes.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Trends in Inpatient Pediatric Polysomnography for Laryngomalacia and Craniofacial Anomalies

Tawfik

Sedaghat

Ishman

2015

Ann Otol Rhinol Laryngol

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“…Çocuklarda da oranı bilinmemekle birlikte yine erkek çocuklarda daha sık olmak üzere genel görülme sıklığı yaklaşık %1 olarak tahmin edilmektedir (6,7). Genel görülme sıklığı yüksek olmamakla birlikte, eşlik eden diğer bazı hastalıklardan, örneğin genetik bozukluklar, reflü, laringomalazi ve kraniyofasiyal anomali varlığında görülme sıklığı %35 gibi oldukça yüksek olabilmektedir (8).…”

Section: Epidemiyolojiunclassified

Çocuk Yaş Grubunda Obstrüktif Uyku Apne Sendromu

Benbir¹,

Karadeniz²

2014

jtsm

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Obstrüktif uyku apne sendromu (OUAS), çocukluk ve erişkin olmak üzere iki gruptan oluşmaktadır. Çocuklarda tam oranı bilinmemektedir; erkek çocuklarda daha sık olmak üzere genel görülme sıklığı yaklaşık %1 olarak tahmin edilmektedir. Predispozan faktörler arasında, ileri yaş önemli bir risk faktörü olmakla birlikte, pediyatrik yaş grubunda erkek cinsiyet, obezite (85. yüzdelik dilim üstü; vücut kütle indeksi (VKİ) >25 kg/m 2 ), hipotiroidi ya da diğer endokrin bozukluklar, kraniyo-fasiyal anatomik bozukluk ve birinci derecede akrabalarda OUAS öyküsü (2-8 kat) olması yer almaktadır. Huzursuz uyku, uykuda çok sık hareket etme ve özellikle boyun ve göğüs bölgesinde olmak üzere terleme hastalarının yaklaşık yarısında mevcuttur. Noktüri pediyatrik yaş grubunda enürezis noktürna şeklinde kendini gösterebilir. Gastro-özefajeal reflü, gece ağız açıklığı ve ağız suyun akması da çocuk yaş grubu OUAS hastalarında sık karşılaşılan şikayetlerdir. OUAS çocuk yaş grubunda da kardiyovasküler hastalıklar için risk oluşturmaktadır. OUAS'lı çocuklarda kan basıncı, sempatik sinir sistem aktivitesi/parasempatik sinir sistem aktivitesi oranı ve noradrenalin düzeyleri anlamlı olarak yüksek saptanmıştır. Uyku apnesinin küçük yaşlarda dahi noktürnal sempatik aktivasyon ile seyrettiği ve buna bağlı olarak ikincil kardiyovasküler komplikasyonlara yol açabileceği bilinmelidir. Cerrahi tedavi erişkinlere kıyasla çocuklarda çok daha ön planda düşünülmekte ve pozitif havayolu basıncı tedavisi ile birlikte birincil tedavi basamağını oluşturmaktadır. (JTSM 2014;2:38-42) Anah tar Ke li me ler: Obstrüktif uyku apne sendromu, çocuk yaş grubu, kardiyovasküler komplikasyonlar, cerrahi tedavi, pozitif havayolu basıncı tedavisi Obstructive sleep apnea syndrome (OSAS) is divided into two categories; in adults and in children. Although its exact incidence in pediatric age group is not well-known, it is suggested as occurring in approximately 1% of young children. Although advanced age is a very important risk factor for OSAS, some amongst the predisposing factors for OSAS in children are male gender, obesity (above 85 th percentile; body mass index >25 kg/m 2 ), hypothyroidism or other endocrine disorders, craniofacial abnormalities and the family history of OSAS in-first degree relatives (2-8 times). Nonrestorative sleep, frequent body movements during sleep and sweating especially in the neck and chest area, are the symptoms observed in almost half of the patients. Nocturia may manifest itself as nocturnal enuresis in the pediatric age group. Gastroesophageal reflux and open mouth saliva drooling during sleep are also commonly encountered in children with OSAS. OSAS is also an important risk factor for cardiovascular diseases in the pediatric age group. Increased blood pressure, sympathetic and parasympathetic nervous system activities and noradrenalin levels are reported to be common in children with OSAS. It should be noted by the physicians that even in youngl age, sleep apnea is associated with increased nocturnal sympathetic activity, and ther...

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“…5 Bazı genetik bozuklukların varlığı, obezite ve kısa ve kalın boyun, retrognati, mikrognati, makroglossi, hipertrofik tonsil ve adenoidler, büyük uzun yumuşak damak gibi kraniyofasiyal anomaliler hastalıkla ilişkili predispozan faktörler olarak gös-terilmektedir. 6 Klinik semptomlar arasında ise tanıklı apne, huzursuz uyku, uyku sırasında çok hareket etme belirtilmektedir. Ancak çocukların uyku sırasında boğuluyormuş gibi hissetmeleri ve nefes alamadıklarını tarif etmeleri daha nadir karşılaşılan bir durumdur.…”

unclassified

The Role of Orthodontics in Diagnosis and Treatment Planning of Pediatric Obstructive Sleep Apnea Syndrome: Case Report

Tuncer¹,

Bavbek²

2016

Turkiye Klinikleri J Dental Sci Cases

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Obstructive sleep apnea in infancy: A 7‐year experience at a pediatric sleep center

Cited by 40 publications

References 44 publications

Trends in Inpatient Pediatric Polysomnography for Laryngomalacia and Craniofacial Anomalies

Trends in Inpatient Pediatric Polysomnography for Laryngomalacia and Craniofacial Anomalies

Çocuk Yaş Grubunda Obstrüktif Uyku Apne Sendromu

The Role of Orthodontics in Diagnosis and Treatment Planning of Pediatric Obstructive Sleep Apnea Syndrome: Case Report

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