Obstructive sleep apnea in children with cystic fibrosis on highly effective modulator therapy
Aarti Shakkottai,
Stephany Kim,
Ron B. Mitchell
Abstract:IntroductionObstructive sleep apnea (OSA) is common in children with cystic fibrosis (CF). Highly effective modulator therapies (HEMT) have led to improved sinopulmonary disease, but whether this translates to a lower frequency of OSA is unknown.MethodsWe conducted a single center retrospective review of polysomnographic (PSG) data from 2012 to 2023 in patients aged 0–18 years with CF to assess frequency of OSA. Participants were classified based on HEMT status. Logistic regression was used to quantify the ass… Show more
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