Obstructive Sleep Apnea and Hypertension: A Bidirectional Causal Relation

Chatzimavridou-Grigoriadou, Victoria; Mathioudakis, Alexander G.; Corlăteanu, Alexandru; Mathioudakis, Georgios A.; Evangelopoulou, Efstathia

doi:10.2174/1573398x11666150914212040

Cited by 3 publications

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“…Furthermore, OSA is frequently associated with hypertension, atrial fibrillation, stroke, heart failure, and sudden death. We found that 33% of our patients had arterial hypertension and 13.3% diabetes mellitus-type II [ 33 ]. Our study also included a patient with hypercapnic acute respiratory failure with moderate to severe obstruction with forced expiratory volume 1.0 sec (FEV1) of less than one liter.…”

Section: Discussionmentioning

confidence: 99%

Apnea-Hypopnea Index in Chronic Obstructive Pulmonary Disease Exacerbation Requiring Noninvasive Mechanical Ventilation with Average Volume-Assured Pressure Support

Claudett

Lopez

Briones-Claudett³

et al. 2021

Critical Care Research and Practice

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Introduction. This study intends to determine the Apnea-Hypopnea Index in patients hospitalized with acute hypercapnic respiratory failure from chronic obstructive pulmonary disease exacerbation, who require noninvasive ventilation with average volume-assured pressure support (AVAPS), as well as describes the clinical characteristics of these patients. Materials and Methods. We designed a single-center prospective study. The coexistence of Apnea-Hypopnea Index and clinical, gasometric, spirometric, respiratory polygraphy, and ventilatory characteristics were determined. The clinical characteristics found were categorized and compared according to the Apnea-Hypopnea Index (AHI) < 5, AHI 5–15, and AHI >15. A p value <0.05 was considered statistically significant. Results. During the study period, a total of 100 patients were admitted to the ICU with a diagnosis of acute hypercapnic respiratory failure due to COPD exacerbation. 72 patients presented with acute respiratory failure and fulfilled criteria for ventilatory support. Within them, 24 received invasive mechanical ventilation and 48 NIV. After applying the inclusion criteria for this study, 30 patients were eligible. An AHI >5 was present in 24 of the 30 patients recruited (80%). Neck circumference (cm), Epworth scale, and Mallampati score evidenced significant differences when compared to the patient’s AHI <5, AHI 5–15, and AHI >15 ( p < 0.05 ). Furthermore, patients with an AHI >5 had longer hospital admissions, prolonged periods on mechanical ventilation, and a higher percentage of intubation rates. Conclusion. Apnea-Hypopnea Index and chronic obstructive pulmonary disease exacerbation are a frequent association found in patients with acute hypercapnic respiratory failure and COPD exacerbations that require NIV. This association could be a determining factor in the response to NIV, especially when AVAPS is used as a ventilatory strategy.

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Section: Discussionmentioning

confidence: 99%

Apnea-Hypopnea Index in Chronic Obstructive Pulmonary Disease Exacerbation Requiring Noninvasive Mechanical Ventilation with Average Volume-Assured Pressure Support

Claudett

Lopez

Briones-Claudett³

et al. 2021

Critical Care Research and Practice

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“…Especially since this condition is often found to overlap with other obstructive lung disease and patients usually have multiple comorbidities [ 8 ]. The list of health-related conditions implicated with OSAS is striking, and includes diminished neurocognitive function, increased risk of motor vehicle accidents, reduced quality of life, and cardiovascular, neurovascular and metabolic disease [ 9 , 10 ].…”

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confidence: 99%

To sleep, or not to sleep – that is the question, for polysomnography

Corlăteanu

Covanţev

Botnaru

et al. 2017

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As the English dramatist Thomas Dekker wrote, “Sleep is that golden chain that ties health and our bodies together”. One of the most frequently sleep-related disorders (SRD) is obstructive sleep apnoea syndrome (OSAS). OSAS is a relatively “young” disease and at the same time, one of the most important respiratory conditions discovered in the last 50 years due to its incidence, prevalence, health-related impact on the patient’s life and economic burden [1].

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Apnoea detection using ECG signal based on machine learning classifiers and its performances

2023

Journal of Medical Engineering & Technology

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Obstructive Sleep Apnea and Hypertension: A Bidirectional Causal Relation

Cited by 3 publications

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Apnea-Hypopnea Index in Chronic Obstructive Pulmonary Disease Exacerbation Requiring Noninvasive Mechanical Ventilation with Average Volume-Assured Pressure Support

Apnea-Hypopnea Index in Chronic Obstructive Pulmonary Disease Exacerbation Requiring Noninvasive Mechanical Ventilation with Average Volume-Assured Pressure Support

To sleep, or not to sleep – that is the question, for polysomnography

Apnoea detection using ECG signal based on machine learning classifiers and its performances

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