Obstructive Sleep Apnea

Ainge‐Allen, Henry W.; Yee, Brendon J.; Grunstein, Ronald R.

doi:10.1002/9781119695257.ch15

Cited by 1 publication

(2 citation statements)

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“…Obesity is a well‐recognized risk factor in the development of sleep‐disordered breathing. Sleep‐disordered breathing is defined as an abnormal pattern of breathing during sleep and encompasses conditions of varying severity, from snoring to sleep apnea through to obesity hypoventilation syndrome 1 …”

Section: Introductionmentioning

confidence: 99%

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Obstructive sleep apnoea in obesity: A review

Tai,

Phillips,

Yee

et al. 2024

Clinical Obesity

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SummaryObstructive sleep apnea is a common comorbidity that occurs in individuals with obesity. It classically manifests with excessive daytime sleepiness, resulting in reduced quality of life, workplace productivity, and an increased risk of motor vehicle accidents. Weight gain plays an important role in its pathogenesis through worsening upper airway collapsibility, and current treatment options are targeted towards mechanically overcoming upper airway obstruction and weight loss. Continuous positive airway pressure therapy remains the most widely prescribed treatment for obstructive sleep apnea but poor tolerance is a common barrier to effective treatment. Sustainable weight loss is an important treatment option but can be difficult to achieve without bariatric surgery. The recent advances in incretin‐based pharmacotherapies represent a promising avenue not only in achieving long‐term weight loss but also in treating obstructive sleep apnoea and alleviating the burden of its symptoms and comorbidities.

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Section: Introductionmentioning

confidence: 99%

“…Obesity hypoventilation syndrome manifests with respiratory failure and is the most severe presentation of sleep‐disordered breathing occurring at the extremes of obesity 1 . This will not be the focus of this review.…”

Section: Introductionmentioning

confidence: 99%