Obstruction aiguë de l’œsophage par mucilage

Thiolet, C; Vergeau, Bertrand Marie; Mennecier, D; Moulin, Olivier; Nizou, C.; Farret, O

doi:10.1016/s0248-8663(03)00247-9

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…Several human cases of hepatotoxicity following consumption of dietary supplementation containing green tea extracts have been reported by Mazzanti et al [207]. In only 7 of the 34 reported cases, hepatotoxicity has been related to concomitant medications, such as administration of diclofenac [208], paracetamol [209,210], or progestogens [211][212][213], which have been associated with some cases of toxic hepatitis [214]. The remaining 27 cases (80%) confirmed green tea as the main cause of hepatic damage, showing a temporal correlation between the consumption of green tea preparations and the appearance of the side effects.…”

Section: Low Bioavailability and Bioaccessibility Appropriate Doses A...mentioning

confidence: 99%

Foodomics-Based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory Bowel Disease

Pratelli,

Tamburini,

Carlisi

et al. 2023

IJMS

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Inflammatory bowel disease (IBD) is a chronic and progressive inflammatory disorder affecting the gastrointestinal tract (GT) caused by a wide range of genetic, microbial, and environmental factors. IBD is characterized by chronic inflammation and decreased gut microbial diversity, dysbiosis, with a lower number of beneficial bacteria and a concomitant increase in pathogenic species. It is well known that dysbiosis is closely related to the induction of inflammation and oxidative stress, the latter caused by an imbalance between reactive oxygen species (ROS) production and cellular antioxidant capacity, leading to cellular ROS accumulation. ROS are responsible for intestinal epithelium oxidative damage and the increased intestinal permeability found in IBD patients, and their reduction could represent a potential therapeutic strategy to limit IBD progression and alleviate its symptoms. Recent evidence has highlighted that dietary polyphenols, the natural antioxidants, can maintain redox equilibrium in the GT, preventing gut dysbiosis, intestinal epithelium damage, and radical inflammatory responses. Here, we suggest that the relatively new foodomics approaches, together with new technologies for promoting the antioxidative properties of dietary polyphenols, including novel delivery systems, chemical modifications, and combination strategies, may provide critical insights to determine the clinical value of polyphenols for IBD therapy and a comprehensive perspective for implementing natural antioxidants as potential IBD candidate treatment.

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Section: Low Bioavailability and Bioaccessibility Appropriate Doses A...mentioning

confidence: 99%

Foodomics-Based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory Bowel Disease

Pratelli,

Tamburini,

Carlisi

et al. 2023

IJMS

View full text Add to dashboard Cite

show abstract

Foodomics-based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory Bowel Disease

Pratelli,

Tamburini,

Carlisi

et al. 2023

Preprint

View full text Add to dashboard Cite

Inflammatory Bowel Disease (IBD) is a chronic and progressive inflammatory disorder affecting the gastrointestinal tract (GT) caused by a wide range of genetic, microbial, and environmental factors. IBD is characterized by chronic inflammation, decreased gut microbial diversity and dysbiosis, with a lower amount of beneficial bacteria and a concomitant increase of pathogenic species. It is well known that dysbiosis is closely related to the induction of inflammation and oxidative stress, this last caused by an imbalance between reactive oxygen species (ROS) production and cellular antioxidant capacity that leads to cellular ROS accumulation. ROS are responsible for the intestinal epithelium oxidative damage and the increased intestinal permeability found in IBD patients and their reduction could represent a potential therapeutic strategy to limit the IBD progression and alleviate its symptom. Recent evidence highlighted that dietary polyphenols, natural antioxidants, are able to maintain redox equilibrium in the GT preventing gut dysbiosis, intestinal epithelium damage and radical inflammatory responses. Here, we suggest that the relatively new foodomics approaches, together with new technologies for promoting the antioxidative properties of dietary polyphenols, including novel delivery systems, chemical modifications and combination strategies, may provide critical insight to determine the clinical value of polyphenols for IBD therapy and a comprehensive perspective for implementing natural antioxidants as potential IBD candidate treatment.

show abstract

Obstruction aiguë de l’œsophage par mucilage

Cited by 2 publications

References 4 publications

Foodomics-Based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory Bowel Disease

Foodomics-Based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory Bowel Disease

Foodomics-based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory Bowel Disease

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