Obstetrical Outcomes among Women with Extrapulmonary Tuberculosis

Jana, Narayan; Vasishta, Kala; Saha, Subhas Chandra; Ghosh, Kanjaksha

doi:10.1056/nejm199908263410903

Cited by 121 publications

(125 citation statements)

References 16 publications

(28 reference statements)

Supporting

Mentioning

112

Contrasting

Unclassified

Order By: Relevance

“…Our finding was consistent with prior studies that found that women with TB had a higher risk of LBW 7,8,10 and SGA infants, 8 as compared with unaffected women. Previous studies investigating the pregnancy outcomes for women with TB have been conducted in western countries, and have been restricted to small clinical samples.…”

Section: Discussionsupporting

confidence: 93%

“…6 Similarly inconsistent results have been observed for the effect of TB on pregnancy outcomes. Some studies have found that TB in pregnant women has been associated with increased risks to infants, including prematurity, 7-9 low birthweight (LBW), 7,8,10 and small for gestational age (SGA) infants, 8 as compared with the infants of women without TB. However, other studies have documented no difference in fetal outcomes between mothers with TB and unaffected mothers.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Increased risk of low birthweight and small for gestational age infants among women with tuberculosis

Lin

Chen

2010

BJOG

View full text Add to dashboard Cite

Objective As the relationship between tuberculosis (TB) and fetal outcomes remains unclear, this study used a 3-year nationwide population-based data set to determine the risk of adverse pregnancy outcomes [low birthweight (LBW), preterm birth and small for gestational age (SGA) infants] among women with TB.Design A cross-sectional retrospective study.Setting Taiwan.Sample Linking the Taiwan birth certificate registry and the Taiwan National Health Insurance Research Dataset, we identified 761 women who gave birth from 2001 to 2003 and who had received medication treatment for TB during their pregnancy, together with 3805 unaffected women matched in terms of age and year of delivery.Methods Conditional logistic regression analyses were performed to compare the risk of LBW, preterm birth and SGA for mothers with TB and unaffected mothers.Main outcome measures The risk of LBW, preterm birth and SGA.Results Mothers diagnosed with TB had significantly higher percentages of LBW (8.5 versus 6.4%, P = 0.033) and SGA (19.7 versus 16.7%, P = 0.048) infants than unaffected mothers. However, there was no significant difference in preterm birth (8.0 versus 8.0%, P = 0.961) between these two groups. The adjusted odds ratios of having LBW and SGA infants for mothers with TB were 1.35 (95% CI = 1.01-1.81) and 1.22 (95% CI = 1.00-1.49), respectively, compared with unaffected mothers.Conclusions We concluded that women diagnosed with TB during pregnancy are at increased risk for having LBW and SGA babies, compared with unaffected mothers. We suggest that clinicians should make women with TB aware of the potential risks before planning a child.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Increased risk of low birthweight and small for gestational age infants among women with tuberculosis

Lin

Chen

2010

BJOG

View full text Add to dashboard Cite

show abstract

“…It is an insidious disease and occurrence of symptoms takes years (8). A great majority of GT occurs during the reproductive years (before 40 years of age), as the endometrium has a very rich medium to regenerate for MTB during the fertile period, and the disease is rarely encountered in the postmenopausal period (9). Granulomas develop in the endometrial tissue and replace the endometrial glands.…”

Section: Discussionmentioning

confidence: 99%

“…There is insufficient data about the management of GT. Similar to PT treatment, long-term multi-drug regimens are generally used (9). Surgery should be performed 6-8 weeks following the medical treatment, as the medical treatment facilitates the surgical procedure reducing perioperative complications (5,6).…”

Section: Discussionmentioning

confidence: 99%

A Successful Live Twin Birth by In vitro Fertilization in an Untreated Patient with Silent Genital Tuberculosis

İnal

Inal

2015

Electron J Gen Med

View full text Add to dashboard Cite

show abstract

“…Extrapulmonary tuberculosis does affect pregnancy adversely. 14 The complications of tuberculosis include chronic anaemia, threatened miscarriage, premature prelabour rupture of membranes 15 and preterm labour. Pregnant women are more likely to experience chorioamnionitis, 16 postpartum anaemia, blood transfusion, pneumonia, acute respiratory distress syndrome and mechanical ventilation.…”

Section: Maternal Complicationsmentioning

confidence: 99%

Tuberculosis in Pregnancy: Delayed Diagnosis, Lost Lives

Ngwenya¹

2017

Pulm Res Respir Med Open J

View full text Add to dashboard Cite

Tuberculosis still remains an important global health disease, killing many people annually. Yet it is a preventable cause of death. Maternal mortality rates due to tuberculosis and HIV/AIDS in Sub-Saharan Africa make up a significant proportion of maternal deaths. It remains a disease of poverty, overcrowding and underdevelopment. Pregnancy increases maternal and fatal mortality in AIDS-infected women. In pregnancy it can be a challenging diagnosis to make, delaying treatment that could lead to adverse outcomes. Clinicians working in high prevalence areas of tuberculosis and those looking after immunocompromised patients should maintain a high index of suspicion. Developing countries must be helped to develop by the world financial institutions with debt reduction. The Sustainable Development Goal aims to end tuberculosis related deaths, transmission and catastrophic costs by 2030. Tuberculosis is a preventable death, the world must act together to prevent unnecessary deaths.

show abstract

Obstetrical Outcomes among Women with Extrapulmonary Tuberculosis

Abstract: Extrapulmonary tuberculosis that is confined to the lymph nodes has no effect on obstetrical outcomes, but tuberculosis at other extrapulmonary sites does adversely affect the outcome of pregnancy.

Cited by 121 publications

References 16 publications

Increased risk of low birthweight and small for gestational age infants among women with tuberculosis

Increased risk of low birthweight and small for gestational age infants among women with tuberculosis

A Successful Live Twin Birth by In vitro Fertilization in an Untreated Patient with Silent Genital Tuberculosis

Tuberculosis in Pregnancy: Delayed Diagnosis, Lost Lives

Contact Info

Product

Resources

About