Obstetric Hemorrhage Current Management and Usefulness of Protocols, Checklist, Drills

Prophylactic use of tranexamic acid for reducing postpartum hemorrhage in vaginal delivery

“…[8][9][10] The treatment of postpartum haemorrhage may also include volume replacement for blood loss, and various surgical procedures including uterine compression sutures, arterial ligation, selective artery embolisation, intrauterine tamponade and hysterectomy. 11,12 Tranexamic acid, an anti-fibrinolytic agent, reduces the incidence of bleeding in elective surgery. [13][14][15] In addition to uterotonic agents which reduce blood loss due to uterine atony, other drugs like anti-fibrinolytic agents and recombinant factor VIIa could be used to control blood loss by effectively ABSTRACT Background: The use of anti-fibrinolytic therapy has potential to reduce obstetric blood loss due to profound changes that take place in the fibrinolytic system during normal childbirth.…”