Obstetric and perinatal histories of children who died unexpectedly (cot death).

Protestos, C. D.; Carpenter, R. G.; McWeeny, P M; Emery, John L.

doi:10.1136/adc.48.11.835

Cited by 84 publications

(7 citation statements)

References 6 publications

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“…Our observed mean parity of the SIDS mothers is similar to those of another California study, 19 although less than that of an English study. 20 However, we did note lower mean maternal age and hematocrits in our case group compared to controls matched for parity (group 2). This study corroborates two other studies 20 -21 reporting more frequent instances of antepartum bleeding in the pregnancies of SIDS mothers versus controls.…”

Section: Discussioncontrasting

confidence: 56%

Placental Pathology is not Predictive for Sudden Infant Death Syndrome (SIDS)

Denmead¹,

Ariagno²,

Carson³

et al. 1987

Amer J Perinatol

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A previous report has suggested an increased incidence of chorioamnionitis in the placentae of sudden infant death syndrome (SIDS) victims. To further evaluate placental pathology in SIDS, 27 cases were identified from coroner's records and matched to two control groups. Both control groups were matched for birthweight, gestational age, and season, with the second also matched for maternal race, infant sex, blood type B, and maternal parity. No significant increase in chorioamnionitis or other placental abnormalities were found in SIDS victims when controlling for prematurity, which is a factor related to chorioamnionitis. An increased incidence of vaginal bleeding (P less than 0.04) and possibly substance abuse or anemia at delivery was found in SIDS mothers. There were more premature and black infants found in the SIDS group compared with the general birth population, and also lower five-minute Apgar scores (P less than 0.02) compared to matched controls. Analysis of the second control group match, including infant Apgar scores, maternal hematocrit, maternal age, and complications of pregnancy and delivery, did not influence any of our conclusions. The data suggests that matching for prematurity may be important in identifying the strength of additional risk factors for SIDS, since the risk factors for SIDS and premature delivery are similar.

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Section: Discussioncontrasting

confidence: 56%

Placental Pathology is not Predictive for Sudden Infant Death Syndrome (SIDS)

Denmead¹,

Ariagno²,

Carson³

et al. 1987

Amer J Perinatol

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“…With regard to the unexpected deaths at home, only one was completely unexplained (group D); there were 21 children in whom gross acute disease was present (group B) and 18 cases showing the presence of minor acute disease (group C) (Protestos, Carpenter, McWeeny & Emery 1973). Their ages ranged from 3 days to 16 months.…”

Section: Resultsmentioning

confidence: 97%

The carotid body—a quantitative assessment in children

1977

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The volume of the glomic tissue in the carotid bodies of 100 infants between the ages of 29 weeks gestation and 9 1/2 years has been determined by serial sections and point counting. There is a 10-fold variation in the size of the carotid body and the volume of glomic tissue at all ages studied. Forty of the infants died as unexpected deaths at home. No increase in size of the carotid body is apparent in the majority of these deaths but there is a probability that enlargement occurs in some children dying at the age of one year or older. Ranges of values and means are presented for the carotid body glomic tissue volume from birth to 9 1/2 years.

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“…Thoman et al, on the other hand, suggested that the relevant anomaly is one involving rapid respiration and the absence of normal respiratory pauses. Anderson and Rosenblith, as well as Protestos et al (1973), also support some kind of respiratory-aberration hypothesis, by documenting that those infants who die of SIDS usually have histories of perinatal/ neonatal respiratory distress. Based on data of the National Collaborative Perinatal Project, the studies of and Lipsitt et al (1979) show that respiratory abnormalities were present at birth, months before the infants died.…”

Section: Crib Deathmentioning

confidence: 93%