Obsessive-compulsive disorder during the COVID-19 pandemic

Ameringen, Michael Van; Patterson, Beth; Turna, Jasmine; Lethbridge, Grace; Bergmann, Carolina Goldman; Lamberti, Nina; Rahat, Maryam; Sideris, Beth; Francisco, Ana Paula; Fineberg, Naomi; Pallanti, Stefano; Grassi, G; Vismara, Matteo; Albert, Umberto; Shavitt, Roseli Gedanke; Hollander, Eric; Feusner, Jamie D.; Rodriguez, Carolyn I.; Morgado, Pedro; Dell’Osso, Bernardo

doi:10.1016/j.jpsychires.2022.02.001

Cited by 16 publications

(16 citation statements)

References 33 publications

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“…Indeed, stressful life events may precipitate or predispose individuals to the development of OCD symptoms. The intense focus on the potential danger of contamination, as well as the COVID 19 infection, may induce the onset of OCD manifestations in vulnerable subjects, even after months of healing from the disease [ 136 ]. Currently, except for epidemiological findings, there are no studies specifically aimed at establishing whether and how COVID-19 infection itself could lead to de novo OCD symptoms or exacerbation of symptoms in people with OCD.…”

Section: Neuropsychiatric Consequences Of Covid-19mentioning

confidence: 99%

Astrocytes and the Psychiatric Sequelae of COVID-19: What We Learned from the Pandemic

Steardo

Scuderi

2022

Neurochem Res

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COVID-19, initially regarded as specific lung disease, exhibits an extremely broad spectrum of symptoms. Extrapulmonary manifestations of the disease also include important neuropsychiatric symptoms with atypical characteristics. Are these disturbances linked to stress accompanying every systemic infection, or are due to specific neurobiological changes associated with COVID-19? Evidence accumulated so far indicates that the pathophysiology of COVID-19 is characterized by systemic inflammation, hypoxia resulting from respiratory failure, and neuroinflammation (either due to viral neurotropism or in response to cytokine storm), all affecting the brain. It is reasonable to hypothesize that all these events may initiate or worsen psychiatric and cognitive disorders. Damage to the brain triggers a specific type of reactive response mounted by neuroglia cells, in particular by astrocytes which are the homeostatic cell par excellence. Astrocytes undergo complex morphological, biochemical, and functional remodeling aimed at mobilizing the regenerative potential of the central nervous system. If the brain is not directly damaged, resolution of systemic pathology usually results in restoration of the physiological homeostatic status of neuroglial cells. The completeness and dynamics of this process in pathological conditions remain largely unknown. In a subset of patients, glial cells could fail to recover after infection thus promoting the onset and progression of COVID-19-related neuropsychiatric diseases. There is evidence from post-mortem examinations of the brains of COVID-19 patients of alterations in both astrocytes and microglia. In conclusion, COVID-19 activates a huge reactive response of glial cells, that physiologically act as the main controller of the inflammatory, protective and regenerative events. However, in some patients the restoration of glial physiological state does not occur, thus compromising glial function and ultimately resulting in homeostatic failure underlying a set of specific neuropsychiatric symptoms related to COVID-19.

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Section: Neuropsychiatric Consequences Of Covid-19mentioning

confidence: 99%

Astrocytes and the Psychiatric Sequelae of COVID-19: What We Learned from the Pandemic

Steardo

Scuderi

2022

Neurochem Res

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“…A study from Netherlands reported similar results with our study. Individuals who reported increase in TV-watching and changing in sleeping and daily communication with their loved ones reported that their OCD symptoms worsened (36). Numerous factors, including the daily provision of new information concerning the disease, uncertainty about when the pandemic would come to an end, and the adoption of new measures daily both increased stress and anxiety, and led to the emergence of obsessions about cleanliness, or the worsening of existing obsessions (37).…”

Section: Discussionmentioning

confidence: 99%

COVID-19-Related Obsessions and Its Predictors: A Community- Based Research in Turkey

Tanrıverdi

Cevheroğlu

Özkurt

et al. 2023

Clinical and Experimental Health Sciences

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Objective: This study aims to investigate the psychological effects of the COVID-19 pandemic on the Turkish society and identify COVID-19-related obsessions and predictive factors. Methods: This cross-sectional study was performed with 859 volunteer participants. Data were collected using an online questionnaire between 01 and 08 June 2020. A sociodemographic information form, Depression, Anxiety and Stress Scale-21 (DASS-21), Impact of Event Scale-Revised (IES-R), and Obsession with COVID-19 Scale (OSC), were used as data collection tools. Data were analysed using SPSS 20 statistical software. Results: The mean age of the participants was 40.41± 13.69 (18-70), 55.3% were women, and %63.7 were married. Cleaning habits increased during the pandemic in 76% of the participants. The prevalence of depression, anxiety, and stress symptoms were 36.9%, 42.3%, and 18.2%, respectively. Depression was severe or very severe in 6.3% of the participants, anxiety in 15.4%, and stress in 4.3%. Post-traumatic stress disorder (PTSD) was determined in 11.3% of the participants, and COVID-19-related obsessions in 17.6%. Obsessions were greater in the variables of eating (r= 0.26, p

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“…The consequences of COVID-19 have negative effects on both physical and mental health. Especially for people with obsessive-compulsive disorder, the COVID-19 pandemic has turned out to be a huge stressor [23]. Many studies have shown an increase in OCD symptoms during a pandemic, which may also be due to overlapping recommendations for protection against infection with symptoms of OCD [23,26,44,45,46].…”

Section: Discussionmentioning

confidence: 99%

The impact of COVID-19 on obsessive-compulsive disorder - literature review

Grabowy

Drożak

Milanowska

2022

J Educ Health Sport

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Introduction: COVID-19 appeared in 2019. The first outbreak of the disease was in China, but it quickly spread to other countries, thus becoming a pandemic. This caused a tremendous stress and anxiety among the public, which also had a negative impact on their mental health. People with obsessive-compulsive disorder are especially sensitive in this respect. The aim of the study: Paying attention to the correlation between exacerbation of obsessive-compulsive symptoms and COVID-19 pandemic. Material and method: The research was done using PubMed and Google Scholar articles about the topic of: obsessive-compulsive disorder, COVID-19 pandemic, stress, mental health. Description of the state of knowledge: According to many studies, the COVID-19 pandemic has negatively impacted mental health of people with obsessive-compulsive disorder. The stress related to the pandemic resulting from concerns about being infected exacerbated the symptoms of obsessive-compulsive disorder. Doctors should pay close attention to OCD patients during pandemic and provide them with the treatment they need. Summary: Research results confirmed that COVID-19 contributed to the deterioration of symptoms in people with obsessive-compulsive disorder.

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Obsessive-compulsive disorder during the COVID-19 pandemic

Cited by 16 publications

References 33 publications

Astrocytes and the Psychiatric Sequelae of COVID-19: What We Learned from the Pandemic

Astrocytes and the Psychiatric Sequelae of COVID-19: What We Learned from the Pandemic

COVID-19-Related Obsessions and Its Predictors: A Community- Based Research in Turkey

The impact of COVID-19 on obsessive-compulsive disorder - literature review

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