Observer Variation in Quantitative Assessment of Rheumatoid Arthritis Part II. A Simplified Scoring System

Kaye, Jeremy J.; Nance, E. Paul; Callahan, Leigh F.; Carroll, Frank E.; Winfield, Alan C.; Earthman, Webb J.; Phillips, Keith A.; Fuchs, Howard A.; Pincus, Theodore

doi:10.1097/00004424-198701000-00006

Cited by 38 publications

(4 citation statements)

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“…As in our previous studies (16,17,23), no equivocal scores ( = I) were recorded in this study. Our method is a modification of the systems proposed by Sharp et al (4) and Genant (8), but differs from those systems in 3 respects: 1) joints were scored not only for erosion and joint space narrowing, but also for malalignment, as Scott and coworkers did in their study (13); 2) a number ofjoints were excluded or combined ( Figure I ) (23); and 3) no equivocal scores ( = 1) were used (16,17,23). The hand and wrist joints evaluated for joint space narrowing, erosion, and malalignment are shown in Figure 1.…”

Section: Joint Space Erosion Ma La Llgnhlen T Narrowingsupporting

confidence: 77%

Radiographic and joint count findings of the hand in rheumatoid arthritis. related and unrelated findings

Fuchs

Callahan

Kaye

et al. 1988

Arthritis & Rheumatism

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Radiographic and physical joint count findings of the hands and wrists of 148 patients with rheumatoid arthritis (RA) were analyzed in a cross‐sectional study. Quantitative radiographic scores for joint space narrowing, erosion, and malalignment were correlated highly with joint count scores for limitation of motion and deformity, and were correlated at considerably lower levels with joint swelling scores. Radiographic scores, however, were not correlated at all with joint count tenderness scores. That 2 of the most widely used indices of RA disease activity, radiographic erosion scores and joint count scores for tenderness, were independent of one another at a selected timepoint, should be considered in the design of clinical trials and long‐term observation of patients with RA.

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Section: Joint Space Erosion Ma La Llgnhlen T Narrowingsupporting

confidence: 77%

Radiographic and joint count findings of the hand in rheumatoid arthritis. related and unrelated findings

Fuchs

Callahan

Kaye

et al. 1988

Arthritis & Rheumatism

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“…We have sought to quantitate the clinical status of RA patients under routine care in our clinic using traditional articular and radiographic measures (12), as well as questionnaires, to assess difficulty, dissatisfaction, and change in capacity to perform activities of daily living (ADL) (13). Initial efforts to assess pain, using available scales, during routine care in our clinic, yielded suboptimum results.…”

mentioning

confidence: 99%

Quantitative pain assessment for routine care of rheumatoid arthritis patients, using a pain scale based on activities of daily living and a visual analog pain scale

Callahan

Brooks

Summey

et al. 1987

Arthritis & Rheumatism

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105

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Pain was assessed quantitatively as a component of routine visits of 385 outpatients with rheumatoid arthritis, using a pain scale based on activities of daily living (ADL) and a visual analog scale. The ADL pain scale met psychometric criteria for validity and reliability. Scores on the 2 pain scales were correlated significantly with one another and with other measures of disease status, including joint count, grip strength, walking time, button test, morning stiffness, erythrocyte sedimentation rate, global self-assessment, ADL difficulty, and ADL dissatisfaction scales. Correlations of ADL pain scale scores with other measures were higher than were correlations of visual analog scale scores with other measures, in both unadjusted and adjusted analyses. Significantly more patients completed the ADL pain scale without assistance than the number of those who completed the visual analog pain scale. The ADL pain scale was more sensitive to problems in ADL than were the ADL scales for difficulty and dissatisfaction. The ADL and visual analog pain scales appear to

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“…It is also likely, given the nonlinear nature of radiographic severity [28], that the baseline level of abnormality may influence the true rate of progression [28]. Second, as with any method, it depends on the reading method: Sharp [28], van der Heijde-modified Sharp [20,29,30,31], Larsenmodified Larsen [31], Scott-modified Larsen [32,33], and several others [34][35][36][37] may give different results. Third, the predicted rate of progression is derived from actual data, but the observed rate of progression after treatment is predicted on continued treatment effect after the conclusion of the trial.…”

Section: What Is Radiographic Progression?mentioning

confidence: 99%

Radiography of rheumatoid arthritis in the time of increasing drug effectiveness

Wolfe

Strand²

2001

Curr Rheumatol Rep

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Recent clinical development programs for new therapeutic agents in rheumatoid arthritis have included assessment of radiographic progression comparing changes with treatment to placebo and active controls. Studies now use reliable methods of assessment and sufficient study length to detect radiographic changes. Although patient populations and characteristics differ, and radiographic scoring methods vary, the direction of a series of studies appears to indicate that leflunomide (LEF), methotrexate (MTX), sulfasalazine (SSZ), etanercept, infliximab, and IL-1ra are all effective in retarding radiographic progression, as measured by erosions and joint space narrowing. Interpretation of radiograph data in future trials will be aided by utilization of common reading methods and by continuing comparison across differing rheumatoid arthritis protocol populations.

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Observer Variation in Quantitative Assessment of Rheumatoid Arthritis Part II. A Simplified Scoring System

Cited by 38 publications

References 0 publications

Radiographic and joint count findings of the hand in rheumatoid arthritis. related and unrelated findings

Radiographic and joint count findings of the hand in rheumatoid arthritis. related and unrelated findings

Quantitative pain assessment for routine care of rheumatoid arthritis patients, using a pain scale based on activities of daily living and a visual analog pain scale

Radiography of rheumatoid arthritis in the time of increasing drug effectiveness

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