Observations on Vesicoureteral Reflux and Chronic Pyelonephritis in Adults

Servadio, C; Shachner, A.

doi:10.1016/s0022-5347(17)62034-2

Cited by 15 publications

(1 citation statement)

References 15 publications

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“…The presence of reflux is one of the factors that has been reported to perpetuate and aggravate an infection in the urinary system (12). It is not surprising that the left kidney, not having been traumatized by surgery nor infected by direct injection into the medulla, showed an infection rate only half that of the right kidney.…”

Section: Resultsmentioning

confidence: 99%

Experimental Urinary Tract Infection in Rats Caused by Candida albicans

Miraglia

Renz

1973

Antimicrob Agents Chemother

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The increased clinical use of broad-spectrum antibiotics, immunosuppressives, and anti-inflammatory agents is thought to have contributed to the increased incidence of renal infections due to Candida albicans. To aid in the search for improved anticandidal agents, we developed an experimental model in which C. albicans is injected into the medulla of the surgically exposed kidney of the rat. The ensuing infection is restricted to the urinary tract and can be treated successfully with amphotericin B. This model promises to be of merit in the evaluation of agents potentially useful in treating candidiasis of the urinary tract.

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Section: Resultsmentioning

confidence: 99%

Experimental Urinary Tract Infection in Rats Caused by Candida albicans

Miraglia

Renz

1973

Antimicrob Agents Chemother

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Der ins Erwachsenenalter persistierende Reflux

Altwein

Thüroff

1980

31. Tagung 17. Bis 20. Oktober 1979, München

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The possibility of scar formation due to intrarenal reflux in analgesic nephropathy

Laberke

1981

Virchows Archiv [Pathol Anat]

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Using an autopsy case of a 59-year-old man with analgesic nephropathy, papillary necrosis, and nephrolithiasis, it is shown that analgesic nephropathy may be complicated by damage resulting from intrarenal urine reflux. The morphologic alterations characteristic of intrarenal and/or pyelointerstitial reflux are caused by high intrapelvic pressure values during episodes of renal colic. Bacterially infected and possibly also sterile urine is then forced into the interstitium, directly within the papillary defect or indirectly via the tubular system after rupture of the tubule. The result is a severe interstitial process with inflammation, destruction, and scarring.

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Observations on Vesicoureteral Reflux and Chronic Pyelonephritis in Adults

Cited by 15 publications

References 15 publications

Experimental Urinary Tract Infection in Rats Caused by Candida albicans

Experimental Urinary Tract Infection in Rats Caused by Candida albicans

Der ins Erwachsenenalter persistierende Reflux

The possibility of scar formation due to intrarenal reflux in analgesic nephropathy

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